Featured Research

from universities, journals, and other organizations

Some Forms Of Cancer Behave In An Unexpected Way

Date:
September 16, 2003
Source:
McGill University
Summary:
Tumor size may not be an accurate method of predicting lymph node involvement and disease progression in some breast cancers, according to investigators at the Research Institute of the McGill University Health Centre (MUHC). Their findings show that some types of breast tumors do not "play by the rules" and possibly, are more dangerous than previously believed.

Tumor size may not be an accurate method of predicting lymph node involvement and disease progression in some breast cancers, according to investigators at the Research Institute of the McGill University Health Centre (MUHC). Their findings show that some types of breast tumors do not "play by the rules" and possibly, are more dangerous than previously believed.

Related Articles


"We have identified a group of breast cancer tumors that don't conform to previous observations made in the general population of women with breast cancer," says MUHC geneticist and lead investigator, Dr. William Foulkes. "For these tumors there is only a very weak correlation between tumor size, the local spread of cancer cells and the likely severity of disease."

An associate professor in the Departments of Medicine, Human Genetics and Oncology at McGill University, Foulkes and his colleagues studied over 1500 women with breast cancer. Women with breast cancer who also had a mutation in particular gene, BRCA1, had unusual tumors. These tumors did not behave as expected - there was no clear correlation between tumor size and associated cancer in the axillary lymph nodes. This was not true for breast cancers in the general population, or those related to another breast cancer susceptibility gene, known as BRCA2.

These results are surprising, because previous studies have indicated that BRCA1-related breast cancers tend to behave aggressively. Thus, the preferred route of spread of BRCA1-related breast cancers may be different from other types of breast cancer. According to Foulkes, these observations have important implications for early diagnosis and treatment of women who carry this gene.

###

These findings will be published in the October 15 issue of Cancer and are currently available online at http://www3.interscience.wiley.com/cgi-bin/jissue/104532863.


Story Source:

The above story is based on materials provided by McGill University. Note: Materials may be edited for content and length.


Cite This Page:

McGill University. "Some Forms Of Cancer Behave In An Unexpected Way." ScienceDaily. ScienceDaily, 16 September 2003. <www.sciencedaily.com/releases/2003/09/030916073522.htm>.
McGill University. (2003, September 16). Some Forms Of Cancer Behave In An Unexpected Way. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2003/09/030916073522.htm
McGill University. "Some Forms Of Cancer Behave In An Unexpected Way." ScienceDaily. www.sciencedaily.com/releases/2003/09/030916073522.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins