Featured Research

from universities, journals, and other organizations

Grapes May Minimize Brain Damage In Stroke Victims

Date:
November 27, 2003
Source:
University Of Missouri-Columbia
Summary:
They can happen in a matter of seconds, but can incapacitate people for the rest of their lives. Strokes are sudden, quick and, in many cases, permanent. Researchers at the University of Missouri-Columbia’s School of Medicine believe that help may be as close as the local grocery store’s produce section.

They can happen in a matter of seconds, but can incapacitate people for the rest of their lives. Strokes are sudden, quick and, in many cases, permanent. Researchers at the University of Missouri-Columbia’s School of Medicine believe that help may be as close as the local grocery store’s produce section.

“For years, scientists have advocated drinking a glass of red wine once or twice a day to help with cardiovascular health,” said Grace Sun, a professor of biochemistry and part of a husband-wife research team at MU. “Our research has shown that a compound in red wine or grapes can have a similar impact on brain health, and in some cases, may help minimize the damage to the brain when a stroke occurs.”

When a stroke happens due to a blockage of blood flow to the brain, no oxygen or nutrients can enter the affected region of the brain. Soon after, neurons in the affected area of the brain begin to release excitatory amino acid neurotransmitters that encourage calcium to move into the neurons. This calcium influx generates “reactive oxygen species,” or “free radicals,” that can be very damaging. Studies with animal models indicate that the influx of calcium and generation of free radicals can result in delayed cell death, a process that occurs over the next few days.

However, Sun, and her husband, Albert Sun, a professor of pharmacology at MU, discovered that resveratrol, a compound found in grapes, can absorb the free radicals and stop them from doing any further damage to the brain or individual cells. While some damage to neurons is still sustained, the researchers found a remarkable difference between brain cells that had been treated with resveratrol and those that had not.

“In the study with the animal model, the compound was helpful if taken both before and after a stroke,” Grace Sun said. “We are continuing to search for compounds in our everyday diet that have lasting impacts on our health. This is just one example.”

Red wine contains high amounts of resveratrol, but it is also found in enriched grape skins. The husband and wife team are part of the MU Center for Phytonutrient and Phytochemical Studies directed by Dennis Lubahn, an associate professor of biochemistry. The Center conducts research on botanical compounds and their effects on human health.

This research on resveratrol was published in the Journal of Brain Research and was funded by a $5.7 million grant from the National Institutes of Health.


Story Source:

The above story is based on materials provided by University Of Missouri-Columbia. Note: Materials may be edited for content and length.


Cite This Page:

University Of Missouri-Columbia. "Grapes May Minimize Brain Damage In Stroke Victims." ScienceDaily. ScienceDaily, 27 November 2003. <www.sciencedaily.com/releases/2003/11/031126070238.htm>.
University Of Missouri-Columbia. (2003, November 27). Grapes May Minimize Brain Damage In Stroke Victims. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2003/11/031126070238.htm
University Of Missouri-Columbia. "Grapes May Minimize Brain Damage In Stroke Victims." ScienceDaily. www.sciencedaily.com/releases/2003/11/031126070238.htm (accessed April 18, 2014).

Share This



More Mind & Brain News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Study On Artists' Brain Shows They're 'Structurally Unique'

Study On Artists' Brain Shows They're 'Structurally Unique'

Newsy (Apr. 17, 2014) The brains of artists aren't really left-brain or right-brain, but rather have extra neural matter in visual and motor control areas. Video provided by Newsy
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Are School Dress Codes Too Strict?

Are School Dress Codes Too Strict?

AP (Apr. 16, 2014) Pushing the limits on style and self-expression is a rite of passage for teens and even younger kids. How far should schools go with their dress codes? The courts have sided with schools in an era when school safety is paramount. (April 16) Video provided by AP
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins