Featured Research

from universities, journals, and other organizations

Celiac Disease Is A Risk Factor For Schizophrenia

Date:
February 20, 2004
Source:
Johns Hopkins University Bloomberg School Of Public Health
Summary:
People with a history of the digestive disorder celiac disease are three times more likely to develop schizophrenia than those without the disease, according to a report by Danish researchers and a researcher at the Johns Hopkins Bloomberg School of Public Health.

People with a history of the digestive disorder celiac disease are three times more likely to develop schizophrenia than those without the disease, according to a report by Danish researchers and a researcher at the Johns Hopkins Bloomberg School of Public Health. The report is published in the February 21, 2004, edition of the British Medical Journal.

Celiac disease is an autoimmune disorder that impairs the body's ability to digest the protein gluten, which is found in grains and many other foods. The condition can lead to diarrhea, weight loss and malnutrition. William W. Eaton, PhD, lead author of the report and interim chair of the Department of Mental Health at the School of Public Health, said, "For years, scientists have suspected a link between celiac disease and schizophrenia. Our research shows that the link is moderately strong."

Dr. Eaton and his colleagues examined the records of 7,997 schizophrenic patients admitted to a Danish psychiatric facility for the first time between 1981 and 1998. Those records were compared to Denmark's national patient register to determine if the schizophrenic patients or their parents were previously treated for celiac disease. The researchers also looked for diagnosis of similar digestive disorders not previously associated with schizophrenia, which included dermatitis herpetiformis, Crohn's disease and ulcerative colitis. The researchers found a small number of schizophrenic patients were previously treated for celiac disease or had a parent treated for celiac disease. Both conditions are rare. The prevalence of celiac disease among schizophrenics was 1.5 cases per 1,000 compared to 0.5 cases per 1,000 in the larger control group. After adjusting for other factors associated with schizophrenia, the researchers determined that the risk of schizophrenia was three times greater with a history of celiac disease. Crohn's disease and ulcerative colitis were not associated with an increased risk of schizophrenia.

"More research is needed to understand the link between celiac disease and schizophrenia. The most important question is whether treatment for celiac disease, in the form of a gluten-free diet, would benefit the small proportion of individuals with schizophrenia who are genetically prone to celiac disease but have not been diagnosed with it," said Dr. Eaton.

###

"Coeliac disease and schizophrenia: population based case control study with linkage of Danish national registers" was written by William W. Eaton, Preben Bo Mortensen, Esben Agerbo, Majella Byrne, Ole Mors and Henrik Ewald. Mortensen, Agerbo and Byrne are with the National Centre for Register-Based Research, Aarhus University, Denmark. Mors and Ewald are with the Institute of Basic Psychiatric Research, Aarhus, Denmark.

The research was funded by the Danish National Research Foundation, Stanley Medical Research Institute and the National Institute for Mental Health.


Story Source:

The above story is based on materials provided by Johns Hopkins University Bloomberg School Of Public Health. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins University Bloomberg School Of Public Health. "Celiac Disease Is A Risk Factor For Schizophrenia." ScienceDaily. ScienceDaily, 20 February 2004. <www.sciencedaily.com/releases/2004/02/040220081037.htm>.
Johns Hopkins University Bloomberg School Of Public Health. (2004, February 20). Celiac Disease Is A Risk Factor For Schizophrenia. ScienceDaily. Retrieved August 31, 2014 from www.sciencedaily.com/releases/2004/02/040220081037.htm
Johns Hopkins University Bloomberg School Of Public Health. "Celiac Disease Is A Risk Factor For Schizophrenia." ScienceDaily. www.sciencedaily.com/releases/2004/02/040220081037.htm (accessed August 31, 2014).

Share This




More Health & Medicine News

Sunday, August 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

Reuters - US Online Video (Aug. 30, 2014) California lawmakers pass a bill requiring universities to adopt "affirmative consent" language in their definitions of consensual sex, part of a nationwide drive to curb sexual assault on campuses. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins