Featured Research

from universities, journals, and other organizations

Advanced Small-cell Lung Cancer Patients

Date:
April 1, 2004
Source:
Temple University
Summary:
Oncologists face extremely difficult decisions when treating patients with advanced small-cell lung cancer (SCLC), a less common but more aggressive form of cancer.

Oncologists face extremely difficult decisions when treating patients with advanced small-cell lung cancer (SCLC), a less common but more aggressive form of cancer. Typically, treatment for SCLC entails chemotherapy or radiation. But when the disease is advanced or recurring, patients often are in poor health overall and are less equipped to handle the toxicity and devastation of powerful cancer treatments.

Related Articles


However, according to a retrospective analysis conducted by Joseph Treat, MD, professor of medicine at Temple University School of Medicine and medical director of the Fox Chase-Temple University Cancer Center, even patients with advanced SCLC can tolerate and benefit from the chemotherapy drug topotecan.

Topotecan, the only FDA-approved chemotherapy for recurring SCLC, works by damaging DNA. This action in turn interferes with the division of cancer cells, slowing progression of the disease.

"All patients, regardless of their overall health, tolerated topotecan similarly," said Treat. "And all patients experienced similar benefits related to tumor growth, disease progression and symptom relief." Perhaps most significantly, Treat added, the drug helped the sickest patients improve their overall health and cope better with their day-to-day routines.

"When our patients are in poor health, we often struggle over whether to subject them to any treatment at all and have to carefully weigh the benefit against the potential harm. This analysis identifies a new option for patients who previously had none," said Treat.


Story Source:

The above story is based on materials provided by Temple University. Note: Materials may be edited for content and length.


Cite This Page:

Temple University. "Advanced Small-cell Lung Cancer Patients." ScienceDaily. ScienceDaily, 1 April 2004. <www.sciencedaily.com/releases/2004/04/040401081531.htm>.
Temple University. (2004, April 1). Advanced Small-cell Lung Cancer Patients. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2004/04/040401081531.htm
Temple University. "Advanced Small-cell Lung Cancer Patients." ScienceDaily. www.sciencedaily.com/releases/2004/04/040401081531.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com
What's Different About This Latest Ebola Vaccine

What's Different About This Latest Ebola Vaccine

Newsy (Mar. 26, 2015) — A whole virus Ebola vaccine has been shown to protect monkeys exposed to the virus. Here&apos;s what&apos;s different about this vaccine. Video provided by Newsy
Powered by NewsLook.com
HIV Outbreak Prompts Public Health Emergency In Indiana

HIV Outbreak Prompts Public Health Emergency In Indiana

Newsy (Mar. 26, 2015) — Indiana Gov. Mike Pence says he will bring additional state resources to help stop the epidemic. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins