Featured Research

from universities, journals, and other organizations

Advanced Small-cell Lung Cancer Patients

Date:
April 1, 2004
Source:
Temple University
Summary:
Oncologists face extremely difficult decisions when treating patients with advanced small-cell lung cancer (SCLC), a less common but more aggressive form of cancer.

Oncologists face extremely difficult decisions when treating patients with advanced small-cell lung cancer (SCLC), a less common but more aggressive form of cancer. Typically, treatment for SCLC entails chemotherapy or radiation. But when the disease is advanced or recurring, patients often are in poor health overall and are less equipped to handle the toxicity and devastation of powerful cancer treatments.

However, according to a retrospective analysis conducted by Joseph Treat, MD, professor of medicine at Temple University School of Medicine and medical director of the Fox Chase-Temple University Cancer Center, even patients with advanced SCLC can tolerate and benefit from the chemotherapy drug topotecan.

Topotecan, the only FDA-approved chemotherapy for recurring SCLC, works by damaging DNA. This action in turn interferes with the division of cancer cells, slowing progression of the disease.

"All patients, regardless of their overall health, tolerated topotecan similarly," said Treat. "And all patients experienced similar benefits related to tumor growth, disease progression and symptom relief." Perhaps most significantly, Treat added, the drug helped the sickest patients improve their overall health and cope better with their day-to-day routines.

"When our patients are in poor health, we often struggle over whether to subject them to any treatment at all and have to carefully weigh the benefit against the potential harm. This analysis identifies a new option for patients who previously had none," said Treat.


Story Source:

The above story is based on materials provided by Temple University. Note: Materials may be edited for content and length.


Cite This Page:

Temple University. "Advanced Small-cell Lung Cancer Patients." ScienceDaily. ScienceDaily, 1 April 2004. <www.sciencedaily.com/releases/2004/04/040401081531.htm>.
Temple University. (2004, April 1). Advanced Small-cell Lung Cancer Patients. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2004/04/040401081531.htm
Temple University. "Advanced Small-cell Lung Cancer Patients." ScienceDaily. www.sciencedaily.com/releases/2004/04/040401081531.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins