Featured Research

from universities, journals, and other organizations

Measuring Artificial Viruses To Improve Disease Detection

Date:
July 5, 2004
Source:
National Institute Of Standards And Technology (NIST)
Summary:
A new method developed by researchers at the National Institute of Standards and Technology (NIST) for accurately measuring the concentration of artificial viruses in a solution may ultimately help doctors diagnose diseases like HIV and hepatitis C earlier.

A new method* developed by researchers at the National Institute of Standards and Technology (NIST) for accurately measuring the concentration of artificial viruses in a solution may ultimately help doctors diagnose diseases like HIV and hepatitis C earlier.

Related Articles


These artificial viruses are commercial standards made from the same basic chemical components in RNA (the single stranded version of DNA needed for protein synthesis.) They are constructed to be nearly identical chemically to real viruses but are encased with a protein covering to prevent degradation. The standards are currently used in research laboratories to help check analysis methods for detecting specific types of RNA, but the product has not been approved for clinical use.

What's needed according to NIST researcher Susan Krueger is a standard, reliable way to measure the concentration of artificial RNA in solution. By knowing exactly how much of the "fake" virus is present in a patient sample, a lab can better detect any additional signal caused by real virus molecules. Traditional methods for measuring concentrations don't work well with the new product since the artificial viruses are not infectious.

Instead, NIST scientists measured the concentration of artificial RNA virus solutions using a beam of neutrons as probes. As neutrons pass through the test solution, they interact in very specific ways with particular atoms, providing scientists with detailed information on molecular weight and geometry. This information can be used to very accurately measure the amount of RNA in a given solution. Precise calibration of artificial RNA concentrations may, in turn, allow laboratories to reliably detect lower concentrations of real viruses at earlier stages of infection.

###

The NIST research was conducted in collaboration with the U.S. Army Aberdeen Proving Ground, Aberdeen, Md.

*The researchers presented their work at the second American Conference on Neutron Scattering, held June 6-10, in College Park, Md.


Story Source:

The above story is based on materials provided by National Institute Of Standards And Technology (NIST). Note: Materials may be edited for content and length.


Cite This Page:

National Institute Of Standards And Technology (NIST). "Measuring Artificial Viruses To Improve Disease Detection." ScienceDaily. ScienceDaily, 5 July 2004. <www.sciencedaily.com/releases/2004/07/040705082341.htm>.
National Institute Of Standards And Technology (NIST). (2004, July 5). Measuring Artificial Viruses To Improve Disease Detection. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2004/07/040705082341.htm
National Institute Of Standards And Technology (NIST). "Measuring Artificial Viruses To Improve Disease Detection." ScienceDaily. www.sciencedaily.com/releases/2004/07/040705082341.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
WHO Says Male Ebola Survivors Should Abstain From Sex

WHO Says Male Ebola Survivors Should Abstain From Sex

Newsy (Nov. 28, 2014) — WHO cites four studies that say Ebola can still be detected in semen up to 82 days after the onset of symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins