Featured Research

from universities, journals, and other organizations

Measuring Artificial Viruses To Improve Disease Detection

Date:
July 5, 2004
Source:
National Institute Of Standards And Technology (NIST)
Summary:
A new method developed by researchers at the National Institute of Standards and Technology (NIST) for accurately measuring the concentration of artificial viruses in a solution may ultimately help doctors diagnose diseases like HIV and hepatitis C earlier.

A new method* developed by researchers at the National Institute of Standards and Technology (NIST) for accurately measuring the concentration of artificial viruses in a solution may ultimately help doctors diagnose diseases like HIV and hepatitis C earlier.

These artificial viruses are commercial standards made from the same basic chemical components in RNA (the single stranded version of DNA needed for protein synthesis.) They are constructed to be nearly identical chemically to real viruses but are encased with a protein covering to prevent degradation. The standards are currently used in research laboratories to help check analysis methods for detecting specific types of RNA, but the product has not been approved for clinical use.

What's needed according to NIST researcher Susan Krueger is a standard, reliable way to measure the concentration of artificial RNA in solution. By knowing exactly how much of the "fake" virus is present in a patient sample, a lab can better detect any additional signal caused by real virus molecules. Traditional methods for measuring concentrations don't work well with the new product since the artificial viruses are not infectious.

Instead, NIST scientists measured the concentration of artificial RNA virus solutions using a beam of neutrons as probes. As neutrons pass through the test solution, they interact in very specific ways with particular atoms, providing scientists with detailed information on molecular weight and geometry. This information can be used to very accurately measure the amount of RNA in a given solution. Precise calibration of artificial RNA concentrations may, in turn, allow laboratories to reliably detect lower concentrations of real viruses at earlier stages of infection.

###

The NIST research was conducted in collaboration with the U.S. Army Aberdeen Proving Ground, Aberdeen, Md.

*The researchers presented their work at the second American Conference on Neutron Scattering, held June 6-10, in College Park, Md.


Story Source:

The above story is based on materials provided by National Institute Of Standards And Technology (NIST). Note: Materials may be edited for content and length.


Cite This Page:

National Institute Of Standards And Technology (NIST). "Measuring Artificial Viruses To Improve Disease Detection." ScienceDaily. ScienceDaily, 5 July 2004. <www.sciencedaily.com/releases/2004/07/040705082341.htm>.
National Institute Of Standards And Technology (NIST). (2004, July 5). Measuring Artificial Viruses To Improve Disease Detection. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2004/07/040705082341.htm
National Institute Of Standards And Technology (NIST). "Measuring Artificial Viruses To Improve Disease Detection." ScienceDaily. www.sciencedaily.com/releases/2004/07/040705082341.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins