Featured Research

from universities, journals, and other organizations

Glue-like Polymer Could Replace Sutures Used For Cataract Surgery

Date:
October 11, 2004
Source:
American Chemical Society
Summary:
People who need cataract surgery, but don’t like the prospect of having their eyes sutured, may be in for some good news: A team of researchers has developed a novel, adhesive hydrogel that can be painted over incisions from cataract surgery and offers the potential for faster, improved repair, they say.

People who need cataract surgery, but don’t like the prospect of having their eyes sutured, may be in for some good news: A team of researchers has developed a novel, adhesive hydrogel that can be painted over incisions from cataract surgery and offers the potential for faster, improved repair, they say. The hydrogel may help avoid complications associated with sutures — the most common repair method for those types of incisions — or unsutured incisions that are left to heal on their own, another repair method of cataract surgery.

Cataract surgery is one of the most commonly performed surgical procedures in the United States, with over 1.5 million procedures performed each year, according to the National Eye Institute. The number is expected to increase with the growth in the aging population.

The transparent hydrogel is made of special polymer materials which act like the liquid bandages sold in stores for topical wounds. It is described in the Oct. 13 print issue of the Journal of the American Chemical Society, a peer-reviewed publication of the American Chemical Society, the world’s largest scientific society.

“Sutures can be difficult to care for and are hard on the eyes,” says study leader Mark W. Grinstaff, Ph.D., a chemist and biomedical engineer with Boston University. “Our hydrogel adhesive could ultimately replace the use of sutures for eye surgery altogether and go a long way toward improving patient care.” His co-leader on this project is Terry Kim, M.D., of Duke University Medical Center in Durham, N.C.

In addition to cataracts, Grinstaff says that using a hydrogel adhesive instead of sutures shows promise for repairing eye wounds associated with LASIK surgery, ulcers, corneal and retinal injuries, and others. Although animal and human testing is still needed, he and Dr. Kim believe the hydrogel could be available to physicians in three to four years.

Hydrogels have been used for several years in applications ranging from drug delivery to healing injured blood vessels, but using them to repair eye wounds is novel, Grinstaff says. In the current study, he and his associates crafted a transparent liquid hydrogel with optical properties similar to a human cornea.

Cataracts are characterized by the clouding of the lens, severely limiting vision. In a typical cataract removal procedure, physicians usually cut an incision in the cornea and then break up and remove the damaged lens using ultrasound, replacing it with a synthetic lens. The incision is either sealed with nylon sutures or allowed to “self-seal” on its own.

Both techniques have their drawbacks. Sutures can damage the tissue and increase the risk of inflammation, while self-sealing can be associated with leakage and an increased risk of infection, the researchers say. In some eyes allowed to self-seal, the incision does not always heal on its own and may subsequently require sutures.

In tests with a small number of human cadaver eyes, the researchers demonstrated that treatment with the sealant was potentially easier and much faster than the other procedures, without risking additional tissue damage, and was better at preventing fluid leakage from the eye. The tests involved making 3-mm incisions in 17 cadaver eyes to simulate cataract surgery. Seven eyes were left unrepaired, representing the self-sealing surgery technique; two were repaired with sutures; and eight were repaired with the hydrogel sealant.

The researchers hope to begin animal testing with the hydrogel in the near future.

The National Institutes of Health provided funding for this study.

The American Chemical Society is a nonprofit organization, chartered by the U.S. Congress, with a multidisciplinary membership of more than 159,000 chemists and chemical engineers. It publishes numerous scientific journals and databases, convenes major research conferences and provides educational, science policy and career programs in chemistry. Its main offices are in Washington, D.C., and Columbus, Ohio.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Glue-like Polymer Could Replace Sutures Used For Cataract Surgery." ScienceDaily. ScienceDaily, 11 October 2004. <www.sciencedaily.com/releases/2004/10/041011074905.htm>.
American Chemical Society. (2004, October 11). Glue-like Polymer Could Replace Sutures Used For Cataract Surgery. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2004/10/041011074905.htm
American Chemical Society. "Glue-like Polymer Could Replace Sutures Used For Cataract Surgery." ScienceDaily. www.sciencedaily.com/releases/2004/10/041011074905.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins