Featured Research

from universities, journals, and other organizations

UCLA Scientists Pinpoint Region Of Autism Gene On Chromosome 17

Date:
May 4, 2005
Source:
University Of California Los Angeles -- Health Sciences
Summary:
For the first time, a team of UCLA geneticists have isolated the likely region of an autism gene on chromosome 17 and then successfully duplicated their efforts in a separate population. In an earlier discovery, the scientists were surprised to find that the gene contributes to autism only in boys, perhaps explaining why girls have a dramatically lower risk of developing the disease.

Autism is a complex disease caused by the interaction of multiple genes and environmental influences. As a result, scientists' previous attempts to locate a genetic risk factor have proved inconclusive. No researchers have been able to pinpoint a predisposing gene and then duplicate their efforts -- a key piece of proof required for scientific validity.

For the first time, a team of UCLA geneticists have isolated the likely region of an autism gene on chromosome 17 and then successfully duplicated their efforts in a separate population. In an earlier discovery, the scientists were surprised to find that the gene contributes to autism only in boys, perhaps explaining why girls have a dramatically lower risk of developing the disease.

After twice linking the risk gene to band 17Q21, the UCLA team is now conducting DNA testing to identify the precise site on the chromosome, which will bring them closer to finding the gene mutation. This is the first step to providing better screening and potential treatments for autism.

Authors of the study include Dr. Dan Geschwind, associate professor of neurology; Rita Cantor, adjunct professor of human genetics; Stan Nelson, professor of human genetics; Jennifer Stone, graduate student researcher, at the David Geffen School of Medicine at UCLA.

JOURNAL
The American Journal of Human Genetics, June 2005
http://www.journals.uchicago.edu/AJHG/journal/issues/v76n6/42136/42136.html

FUNDING
National Institute of Mental Health


Story Source:

The above story is based on materials provided by University Of California Los Angeles -- Health Sciences. Note: Materials may be edited for content and length.


Cite This Page:

University Of California Los Angeles -- Health Sciences. "UCLA Scientists Pinpoint Region Of Autism Gene On Chromosome 17." ScienceDaily. ScienceDaily, 4 May 2005. <www.sciencedaily.com/releases/2005/05/050504224433.htm>.
University Of California Los Angeles -- Health Sciences. (2005, May 4). UCLA Scientists Pinpoint Region Of Autism Gene On Chromosome 17. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2005/05/050504224433.htm
University Of California Los Angeles -- Health Sciences. "UCLA Scientists Pinpoint Region Of Autism Gene On Chromosome 17." ScienceDaily. www.sciencedaily.com/releases/2005/05/050504224433.htm (accessed August 1, 2014).

Share This




More Mind & Brain News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dieting At A Young Age Might Lead To Harmful Health Habits

Dieting At A Young Age Might Lead To Harmful Health Habits

Newsy (July 30, 2014) Researchers say women who diet at a young age are at greater risk of developing harmful health habits, including eating disorders and alcohol abuse. Video provided by Newsy
Powered by NewsLook.com
It's Not Just Facebook: OKCupid Experiments With Users Too

It's Not Just Facebook: OKCupid Experiments With Users Too

Newsy (July 29, 2014) If you've been looking for love online, there's a chance somebody has been looking at how you're looking. Video provided by Newsy
Powered by NewsLook.com
How Your Face Can Leave A Good Or Bad First Impression

How Your Face Can Leave A Good Or Bad First Impression

Newsy (July 29, 2014) Researchers have found certain facial features can make us seem more attractive or trustworthy. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins