Featured Research

from universities, journals, and other organizations

UCLA Scientists Pinpoint Region Of Autism Gene On Chromosome 17

Date:
May 4, 2005
Source:
University Of California Los Angeles -- Health Sciences
Summary:
For the first time, a team of UCLA geneticists have isolated the likely region of an autism gene on chromosome 17 and then successfully duplicated their efforts in a separate population. In an earlier discovery, the scientists were surprised to find that the gene contributes to autism only in boys, perhaps explaining why girls have a dramatically lower risk of developing the disease.

Autism is a complex disease caused by the interaction of multiple genes and environmental influences. As a result, scientists' previous attempts to locate a genetic risk factor have proved inconclusive. No researchers have been able to pinpoint a predisposing gene and then duplicate their efforts -- a key piece of proof required for scientific validity.

Related Articles


For the first time, a team of UCLA geneticists have isolated the likely region of an autism gene on chromosome 17 and then successfully duplicated their efforts in a separate population. In an earlier discovery, the scientists were surprised to find that the gene contributes to autism only in boys, perhaps explaining why girls have a dramatically lower risk of developing the disease.

After twice linking the risk gene to band 17Q21, the UCLA team is now conducting DNA testing to identify the precise site on the chromosome, which will bring them closer to finding the gene mutation. This is the first step to providing better screening and potential treatments for autism.

Authors of the study include Dr. Dan Geschwind, associate professor of neurology; Rita Cantor, adjunct professor of human genetics; Stan Nelson, professor of human genetics; Jennifer Stone, graduate student researcher, at the David Geffen School of Medicine at UCLA.

JOURNAL
The American Journal of Human Genetics, June 2005
http://www.journals.uchicago.edu/AJHG/journal/issues/v76n6/42136/42136.html

FUNDING
National Institute of Mental Health


Story Source:

The above story is based on materials provided by University Of California Los Angeles -- Health Sciences. Note: Materials may be edited for content and length.


Cite This Page:

University Of California Los Angeles -- Health Sciences. "UCLA Scientists Pinpoint Region Of Autism Gene On Chromosome 17." ScienceDaily. ScienceDaily, 4 May 2005. <www.sciencedaily.com/releases/2005/05/050504224433.htm>.
University Of California Los Angeles -- Health Sciences. (2005, May 4). UCLA Scientists Pinpoint Region Of Autism Gene On Chromosome 17. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2005/05/050504224433.htm
University Of California Los Angeles -- Health Sciences. "UCLA Scientists Pinpoint Region Of Autism Gene On Chromosome 17." ScienceDaily. www.sciencedaily.com/releases/2005/05/050504224433.htm (accessed March 6, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Friday, March 6, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Former NFL Players Donate Brains to Science

Former NFL Players Donate Brains to Science

Reuters - US Online Video (Mar. 3, 2015) Super Bowl champions Sidney Rice and Steve Weatherford donate their brains, post-mortem, to scientific research into repetitive brain trauma. Jillian Kitchener reports. Video provided by Reuters
Powered by NewsLook.com
Alzheimer's Protein Plaque Found In 20-Year-Olds

Alzheimer's Protein Plaque Found In 20-Year-Olds

Newsy (Mar. 3, 2015) Researchers found an abnormal protein associated with Alzheimer&apos;s disease in the brains of 20-year-olds. Video provided by Newsy
Powered by NewsLook.com
This Nasal Treatment Could Help Ease Migraine Pain

This Nasal Treatment Could Help Ease Migraine Pain

Newsy (Mar. 2, 2015) Researchers gave lidocaine to 112 patients, and about 88 percent of the subjects said they needed less migraine-relief medicine the next day. Video provided by Newsy
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins