Featured Research

from universities, journals, and other organizations

Rethinking Anti-oxidants: Are We On The Right Track?

Date:
August 15, 2005
Source:
Research Australia
Summary:
A leading researcher at the University of New South Wales (UNSW) points out that there is little convincing evidence that dietary antioxidant supplements such as vitamin E prevent heart disease, despite claims to the contrary. Instead there has been a surprise finding, which relates to a synthetic antioxidant.

A leading researcher at the University of New South Wales (UNSW) pointsout that there is little convincing evidence that dietary antioxidantsupplements such as vitamin E prevent heart disease, despite claims tothe contrary.

Instead there has been a surprise finding, which relates to asynthetic antioxidant, the drug Probucol, which is no longer prescribedin Australia.

"There has been a lot of hype which suggested that antioxidantvitamin supplements had a beneficial outcome for cardiovasculardisease. There is no good scientific support for the notion that peoplewho suffer from atherosclerosis, or who are at elevated risk of heartdisease, gain benefit by supplements of vitamin E," said ProfessorRoland Stocker, from the Centre for Vascular Research at UNSW, who willpresent his research at the ISTH Congress in Sydney today.

Stocker reported, "Our research is now leading towards thedevelopment of a new drug, based on Probucol. Probucol was previouslyused to reduce so-called "bad" cholesterol for those with heartdisease, but it also had side effects, such as reducing "good"cholesterol and possibly inducing an irregular heartbeat.

This new compound, which has a similar structure to probucol,is very effective in protecting against atherosclerosis (the principalcause of coronary heart disease) in animal models but doesn't have thesame side effects"

He went onto say, "We have shown that this novelprobucol-analog induces a pathway in the vessel wall which is bothanti-oxidative and anti-inflammatory. The early signs are that itprovides strong protection for blood vessel walls. We are nowprogressing these studies further with a pharmaceutical company."

"This compound potentially represents a new approach fortreating people with or at risk of heart disease � at the source of theproblem in the vessel wall. Vitamin E is not depleted or deficient inpeople with heart disease. It is in my view, a na�ve idea that vitaminE supplements would work," said Stocker.


Story Source:

The above story is based on materials provided by Research Australia. Note: Materials may be edited for content and length.


Cite This Page:

Research Australia. "Rethinking Anti-oxidants: Are We On The Right Track?." ScienceDaily. ScienceDaily, 15 August 2005. <www.sciencedaily.com/releases/2005/08/050811090622.htm>.
Research Australia. (2005, August 15). Rethinking Anti-oxidants: Are We On The Right Track?. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2005/08/050811090622.htm
Research Australia. "Rethinking Anti-oxidants: Are We On The Right Track?." ScienceDaily. www.sciencedaily.com/releases/2005/08/050811090622.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com
Ebola Vaccine Trial Gets Underway at Oxford University

Ebola Vaccine Trial Gets Underway at Oxford University

AFP (Sep. 17, 2014) A healthy British volunteer is to become the first person to receive a new vaccine for the Ebola virus after US President Barack Obama called for action against the epidemic and warned it was "spiralling out of control." Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins