Featured Research

from universities, journals, and other organizations

Rethinking Anti-oxidants: Are We On The Right Track?

Date:
August 15, 2005
Source:
Research Australia
Summary:
A leading researcher at the University of New South Wales (UNSW) points out that there is little convincing evidence that dietary antioxidant supplements such as vitamin E prevent heart disease, despite claims to the contrary. Instead there has been a surprise finding, which relates to a synthetic antioxidant.

A leading researcher at the University of New South Wales (UNSW) pointsout that there is little convincing evidence that dietary antioxidantsupplements such as vitamin E prevent heart disease, despite claims tothe contrary.

Instead there has been a surprise finding, which relates to asynthetic antioxidant, the drug Probucol, which is no longer prescribedin Australia.

"There has been a lot of hype which suggested that antioxidantvitamin supplements had a beneficial outcome for cardiovasculardisease. There is no good scientific support for the notion that peoplewho suffer from atherosclerosis, or who are at elevated risk of heartdisease, gain benefit by supplements of vitamin E," said ProfessorRoland Stocker, from the Centre for Vascular Research at UNSW, who willpresent his research at the ISTH Congress in Sydney today.

Stocker reported, "Our research is now leading towards thedevelopment of a new drug, based on Probucol. Probucol was previouslyused to reduce so-called "bad" cholesterol for those with heartdisease, but it also had side effects, such as reducing "good"cholesterol and possibly inducing an irregular heartbeat.

This new compound, which has a similar structure to probucol,is very effective in protecting against atherosclerosis (the principalcause of coronary heart disease) in animal models but doesn't have thesame side effects"

He went onto say, "We have shown that this novelprobucol-analog induces a pathway in the vessel wall which is bothanti-oxidative and anti-inflammatory. The early signs are that itprovides strong protection for blood vessel walls. We are nowprogressing these studies further with a pharmaceutical company."

"This compound potentially represents a new approach fortreating people with or at risk of heart disease � at the source of theproblem in the vessel wall. Vitamin E is not depleted or deficient inpeople with heart disease. It is in my view, a na�ve idea that vitaminE supplements would work," said Stocker.


Story Source:

The above story is based on materials provided by Research Australia. Note: Materials may be edited for content and length.


Cite This Page:

Research Australia. "Rethinking Anti-oxidants: Are We On The Right Track?." ScienceDaily. ScienceDaily, 15 August 2005. <www.sciencedaily.com/releases/2005/08/050811090622.htm>.
Research Australia. (2005, August 15). Rethinking Anti-oxidants: Are We On The Right Track?. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2005/08/050811090622.htm
Research Australia. "Rethinking Anti-oxidants: Are We On The Right Track?." ScienceDaily. www.sciencedaily.com/releases/2005/08/050811090622.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins