Featured Research

from universities, journals, and other organizations

Rethinking Anti-oxidants: Are We On The Right Track?

Date:
August 15, 2005
Source:
Research Australia
Summary:
A leading researcher at the University of New South Wales (UNSW) points out that there is little convincing evidence that dietary antioxidant supplements such as vitamin E prevent heart disease, despite claims to the contrary. Instead there has been a surprise finding, which relates to a synthetic antioxidant.

A leading researcher at the University of New South Wales (UNSW) pointsout that there is little convincing evidence that dietary antioxidantsupplements such as vitamin E prevent heart disease, despite claims tothe contrary.

Related Articles


Instead there has been a surprise finding, which relates to asynthetic antioxidant, the drug Probucol, which is no longer prescribedin Australia.

"There has been a lot of hype which suggested that antioxidantvitamin supplements had a beneficial outcome for cardiovasculardisease. There is no good scientific support for the notion that peoplewho suffer from atherosclerosis, or who are at elevated risk of heartdisease, gain benefit by supplements of vitamin E," said ProfessorRoland Stocker, from the Centre for Vascular Research at UNSW, who willpresent his research at the ISTH Congress in Sydney today.

Stocker reported, "Our research is now leading towards thedevelopment of a new drug, based on Probucol. Probucol was previouslyused to reduce so-called "bad" cholesterol for those with heartdisease, but it also had side effects, such as reducing "good"cholesterol and possibly inducing an irregular heartbeat.

This new compound, which has a similar structure to probucol,is very effective in protecting against atherosclerosis (the principalcause of coronary heart disease) in animal models but doesn't have thesame side effects"

He went onto say, "We have shown that this novelprobucol-analog induces a pathway in the vessel wall which is bothanti-oxidative and anti-inflammatory. The early signs are that itprovides strong protection for blood vessel walls. We are nowprogressing these studies further with a pharmaceutical company."

"This compound potentially represents a new approach fortreating people with or at risk of heart disease � at the source of theproblem in the vessel wall. Vitamin E is not depleted or deficient inpeople with heart disease. It is in my view, a na�ve idea that vitaminE supplements would work," said Stocker.


Story Source:

The above story is based on materials provided by Research Australia. Note: Materials may be edited for content and length.


Cite This Page:

Research Australia. "Rethinking Anti-oxidants: Are We On The Right Track?." ScienceDaily. ScienceDaily, 15 August 2005. <www.sciencedaily.com/releases/2005/08/050811090622.htm>.
Research Australia. (2005, August 15). Rethinking Anti-oxidants: Are We On The Right Track?. ScienceDaily. Retrieved February 1, 2015 from www.sciencedaily.com/releases/2005/08/050811090622.htm
Research Australia. "Rethinking Anti-oxidants: Are We On The Right Track?." ScienceDaily. www.sciencedaily.com/releases/2005/08/050811090622.htm (accessed February 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, February 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Obama To Outline New Plan For Personalized Medicine

Obama To Outline New Plan For Personalized Medicine

Newsy (Jan. 30, 2015) President Obama is expected to speak with drugmakers Friday about his Precision Medicine Initiative first introduced last week. Video provided by Newsy
Powered by NewsLook.com
NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins