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Novel Mechanism For DNA Replication Discovered

Date:
September 30, 2005
Source:
The Mount Sinai Hospital / Mount Sinai School of Medicine
Summary:
Since the discovery of the structure of DNA, the paradigm for DNA replication has stated that the DNA itself codes for replication. In other words, if a guanine base is on the original strand of DNA then its partner, a cytosine base, will pair to it on the replicated strand. Researchers from Mount Sinai School of Medicine report on the first instance in which a protein provides the coding information.

Since the discovery of the structure of DNA by James Watson and Francis Crick in 1953, the paradigm for DNA replication has stated that the DNA itself codes for the appropriate pairings for replication. In other words, if a guanine base is on the original strand of DNA then its partner, a cytosine base, will pair to it on the replicated strand. In a study published in this week's issue of Science, researchers from Mount Sinai School of Medicine report on the first instance in which a protein, rather than the DNA, provides the coding information.


Story Source:

The above story is based on materials provided by The Mount Sinai Hospital / Mount Sinai School of Medicine. Note: Materials may be edited for content and length.


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The Mount Sinai Hospital / Mount Sinai School of Medicine. "Novel Mechanism For DNA Replication Discovered." ScienceDaily. ScienceDaily, 30 September 2005. <www.sciencedaily.com/releases/2005/09/050930082959.htm>.
The Mount Sinai Hospital / Mount Sinai School of Medicine. (2005, September 30). Novel Mechanism For DNA Replication Discovered. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2005/09/050930082959.htm
The Mount Sinai Hospital / Mount Sinai School of Medicine. "Novel Mechanism For DNA Replication Discovered." ScienceDaily. www.sciencedaily.com/releases/2005/09/050930082959.htm (accessed April 16, 2014).

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