Featured Research

from universities, journals, and other organizations

Study Links Obesity To Liver Failure

Date:
May 25, 2006
Source:
American Gastroenterological Association
Summary:
Researchers have found that obesity can put patients with acute liver failure at increased risk of mortality and other major complications, according to a new study presented today at Digestive Disease Week 2006.

Researchers have found that obesity can put patients with acute liver failure at increased risk of mortality and other major complications, according to a new study presented today at Digestive Disease Week® 2006 (DDW). DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

Related Articles


The connection between diabetes and obesity in the development of non-alcoholic fatty liver disease (NAFLD) has been well established; however, little is known about the possible link between these factors and acute liver failure (ALF). Investigators from Massachusetts General Hospital and the National Institutes of Health-funded Acute Liver Failure Study Group researched this connection and found that although obesity does not appear more prevalent in ALF cases, patients who are obese or morbidly obese have significantly poorer outcomes with ALF. ALF is a serious medical condition in which large portions of the liver quickly become so damaged that the liver is no longer able to function, putting patients at risk of severe complications and death.

Study authors examined 572 patients suffering from ALF and documented body mass index (BMI), prevalence of diabetes and patient outcome. The number of obese patients in the study was consistent with the prevalence of obesity in the general U.S. population. However, the mean BMI score was higher (28.8 versus 26.6) for ALF patients who needed liver transplants or died. In addition, obese ALF patients were almost twice as likely to need a transplant or die as non-obese patients. Finally, obese patients were also more than three times more likely to die post-liver transplant than non-obese patients. Because many of these obese patients have NAFLD, which has been shown to impair liver regeneration, they may have less capacity to regenerate or recover from acute liver failure than their non-obese counterparts.

"While obesity may not be a risk factor for the development of ALF, obese ALF patients are at serious risk of major liver-related complications and death," said Anna Rutherford, M.D., Massachusetts General Hospital and lead study author. "Physicians should encourage patients to maintain a healthy weight to help improve their health and outcome."

Digestive Disease Week® (DDW) is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. Jointly sponsored by the American Association for the Study of Liver Diseases (AASLD), the American Gastroenterological Association (AGA), the American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Surgery of the Alimentary Tract (SSAT), DDW takes place May 20-25, 2006 in Los Angeles, California. The meeting showcases more than 5,000 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology.


Story Source:

The above story is based on materials provided by American Gastroenterological Association. Note: Materials may be edited for content and length.


Cite This Page:

American Gastroenterological Association. "Study Links Obesity To Liver Failure." ScienceDaily. ScienceDaily, 25 May 2006. <www.sciencedaily.com/releases/2006/05/060524223250.htm>.
American Gastroenterological Association. (2006, May 25). Study Links Obesity To Liver Failure. ScienceDaily. Retrieved March 2, 2015 from www.sciencedaily.com/releases/2006/05/060524223250.htm
American Gastroenterological Association. "Study Links Obesity To Liver Failure." ScienceDaily. www.sciencedaily.com/releases/2006/05/060524223250.htm (accessed March 2, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 2, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rehab Robot Helps Restore Damaged Muscles and Nerves

Rehab Robot Helps Restore Damaged Muscles and Nerves

Reuters - Innovations Video Online (Mar. 1, 2015) — A rehabilitation robot prototype to help restore deteriorated nerves and muscles using electromyography and computer games. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) — Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com
Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) — A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) — An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins