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Australian Discovery Could Lead To New Leukemia Treatments

Date:
November 13, 2006
Source:
Deakin University
Summary:
Australian scientists have identified a protein that could hold the key to new leukemia treatments.

Australian scientists have identified a protein that could hold the key to new leukemia treatments.

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The protein--Stat5--was investigated at a laboratory at Deakin University's Melbourne Campus at Burwood, as part of a multicentre international collaboration.

leukemia is a cancer caused by a proliferation of white blood cells. To understand and help prevent the disease, the Deakin researchers are looking for the responsible genes.

Head of the Deakin team, Associate Professor Alister Ward, said the discovery of how the protein acts provides a breakthrough in understanding the onset of leukemia.

"We have found that Stat5 is responsible for making white blood cells overgrow in a particular disease setting that often precedes leukemia," Associate Professor Ward explained.

"On top of this, we have also found that Stat5, when activated, is sufficient on its own to cause white blood cells to overgrow inside a whole organism.

"Together, these findings identify Stat5 as a major player in the process of leukemia progression and is therefore a worthwhile target for intervention."

Associate Professor Ward said the next step in this research was to utilise the model systems established to develop new therapeutics.


Story Source:

The above story is based on materials provided by Deakin University. Note: Materials may be edited for content and length.


Cite This Page:

Deakin University. "Australian Discovery Could Lead To New Leukemia Treatments." ScienceDaily. ScienceDaily, 13 November 2006. <www.sciencedaily.com/releases/2006/11/061106111833.htm>.
Deakin University. (2006, November 13). Australian Discovery Could Lead To New Leukemia Treatments. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2006/11/061106111833.htm
Deakin University. "Australian Discovery Could Lead To New Leukemia Treatments." ScienceDaily. www.sciencedaily.com/releases/2006/11/061106111833.htm (accessed November 27, 2014).

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