Featured Research

from universities, journals, and other organizations

Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness

Date:
February 6, 2007
Source:
American Academy of Sleep Medicine
Summary:
A study published in the February 1st issue of the journal SLEEP provides a first direct demonstration that the "quality" and "intensity" of wakefulness can affect slow-wave activity during subsequent sleep.

A study published in the February 1st issue of the journal SLEEP provides a first direct demonstration that the "quality" and "intensity" of wakefulness can affect slow-wave activity (SWA) during subsequent sleep.

Related Articles


According to Chiara Cirelli, MD, PhD, of the University of Wisconsin-Madison, one of the authors of the study, the importance and novelty of the paper lies in the demonstration that the crucial factor linking physiological waking activity to sleep SWA is synaptic plasticity, notably synaptic potentiation, mediated by brain-derived neurotrophic factor (BDNF) signaling.

"Namely, the study shows that wakefulness associated with exposure to an enriched environment and with high levels of exploratory activity, a condition well known to trigger plastic changes in the brain, leads to increased BNDF expression and increased sleep pressure as compared to wakefulness with low exploratory activity," said Cirelli. "More stringently, the study finds that the amount of exploratory behavior during wakefulness can predict the extent to which BDNF is induced in the cerebral cortex, as well as the extent of the SWA response during subsequent sleep."

Cirelli notes that SWA has been validated as the best current marker of sleep pressure and sleep intensity by more than 30 years of research, and yet there is very poor understanding of the crucial factors that determine how and why sleep pressure increases during wakefulness and decreases during sleep.

"This paper offers a first hint of what may be at least one of the crucial factors linking the 'quality' of wakefulness to the intensity of sleep," added Cirelli.

The study is also novel in the approach used to prove this point, a combination of electroencephalographic, behavioral and molecular methods, said Cirelli, adding that the results of the study strongly support the hypothesis that synaptic plasticity during wakefulness is linked to sleep homeostasis. These findings complement other data recently published by Cirelli and her colleagues showing that the cortical areas more actively involved in the learning of a motor task during waking show the largest increase in SWA during subsequent sleep.

SLEEP is the official journal of the Associated Professional Sleep Societies, LLC, a joint venture of the American Academy of Sleep Medicine (AASM) and the Sleep Research Society.

SleepEducation.com, a Web site maintained by the AASM, provides information about the various sleep disorders that exist, the forms of treatment available, recent news on the topic of sleep, sleep studies that have been conducted and a listing of sleep facilities.


Story Source:

The above story is based on materials provided by American Academy of Sleep Medicine. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Sleep Medicine. "Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness." ScienceDaily. ScienceDaily, 6 February 2007. <www.sciencedaily.com/releases/2007/02/070201082510.htm>.
American Academy of Sleep Medicine. (2007, February 6). Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness. ScienceDaily. Retrieved January 26, 2015 from www.sciencedaily.com/releases/2007/02/070201082510.htm
American Academy of Sleep Medicine. "Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness." ScienceDaily. www.sciencedaily.com/releases/2007/02/070201082510.htm (accessed January 26, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Monday, January 26, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Technology Is Ruining Snow Days For Students

How Technology Is Ruining Snow Days For Students

Newsy (Jan. 25, 2015) — More schools are using online classes to keep from losing time to snow days, but it only works if students have Internet access at home. Video provided by Newsy
Powered by NewsLook.com
Weird Things Couples Do When They Lose Their Phone

Weird Things Couples Do When They Lose Their Phone

BuzzFeed (Jan. 24, 2015) — Did you back it up? Do you even know how to do that? Video provided by BuzzFeed
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) — A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
Amazing Technology Allows Blind Mother to See Her Newborn Son

Amazing Technology Allows Blind Mother to See Her Newborn Son

RightThisMinute (Jan. 23, 2015) — Not only is Kathy seeing her newborn son for the first time, but this is actually the first time she has ever seen a baby. Kathy and her sister, Yvonne, have been legally blind since childhood, but thanks to an amazing new technology, eSight glasses, which gives those who are legally blind the ability to see, she got the chance to see the birth of her son. It&apos;s an incredible moment and an even better story. Video provided by RightThisMinute
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins