Featured Research

from universities, journals, and other organizations

Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness

Date:
February 6, 2007
Source:
American Academy of Sleep Medicine
Summary:
A study published in the February 1st issue of the journal SLEEP provides a first direct demonstration that the "quality" and "intensity" of wakefulness can affect slow-wave activity during subsequent sleep.

A study published in the February 1st issue of the journal SLEEP provides a first direct demonstration that the "quality" and "intensity" of wakefulness can affect slow-wave activity (SWA) during subsequent sleep.

Related Articles


According to Chiara Cirelli, MD, PhD, of the University of Wisconsin-Madison, one of the authors of the study, the importance and novelty of the paper lies in the demonstration that the crucial factor linking physiological waking activity to sleep SWA is synaptic plasticity, notably synaptic potentiation, mediated by brain-derived neurotrophic factor (BDNF) signaling.

"Namely, the study shows that wakefulness associated with exposure to an enriched environment and with high levels of exploratory activity, a condition well known to trigger plastic changes in the brain, leads to increased BNDF expression and increased sleep pressure as compared to wakefulness with low exploratory activity," said Cirelli. "More stringently, the study finds that the amount of exploratory behavior during wakefulness can predict the extent to which BDNF is induced in the cerebral cortex, as well as the extent of the SWA response during subsequent sleep."

Cirelli notes that SWA has been validated as the best current marker of sleep pressure and sleep intensity by more than 30 years of research, and yet there is very poor understanding of the crucial factors that determine how and why sleep pressure increases during wakefulness and decreases during sleep.

"This paper offers a first hint of what may be at least one of the crucial factors linking the 'quality' of wakefulness to the intensity of sleep," added Cirelli.

The study is also novel in the approach used to prove this point, a combination of electroencephalographic, behavioral and molecular methods, said Cirelli, adding that the results of the study strongly support the hypothesis that synaptic plasticity during wakefulness is linked to sleep homeostasis. These findings complement other data recently published by Cirelli and her colleagues showing that the cortical areas more actively involved in the learning of a motor task during waking show the largest increase in SWA during subsequent sleep.

SLEEP is the official journal of the Associated Professional Sleep Societies, LLC, a joint venture of the American Academy of Sleep Medicine (AASM) and the Sleep Research Society.

SleepEducation.com, a Web site maintained by the AASM, provides information about the various sleep disorders that exist, the forms of treatment available, recent news on the topic of sleep, sleep studies that have been conducted and a listing of sleep facilities.


Story Source:

The above story is based on materials provided by American Academy of Sleep Medicine. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Sleep Medicine. "Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness." ScienceDaily. ScienceDaily, 6 February 2007. <www.sciencedaily.com/releases/2007/02/070201082510.htm>.
American Academy of Sleep Medicine. (2007, February 6). Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness. ScienceDaily. Retrieved March 26, 2015 from www.sciencedaily.com/releases/2007/02/070201082510.htm
American Academy of Sleep Medicine. "Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness." ScienceDaily. www.sciencedaily.com/releases/2007/02/070201082510.htm (accessed March 26, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Thursday, March 26, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com
Smartphone Use Changing Our Brain and Thumb Interaction, Say Researchers

Smartphone Use Changing Our Brain and Thumb Interaction, Say Researchers

Reuters - Innovations Video Online (Mar. 25, 2015) European researchers say our smartphone use offers scientists an ideal testing ground for human brain plasticity. Dr Ako Ghosh&apos;s team discovered that the brains and thumbs of smartphone users interact differently from those who use old-fashioned handsets. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Many Don't Know They Have Alzheimer's, But Their Doctors Do

Many Don't Know They Have Alzheimer's, But Their Doctors Do

Newsy (Mar. 24, 2015) According to a new study by the Alzheimer&apos;s Association, more than half of those who have the degenerative brain disease aren&apos;t told by their doctors. Video provided by Newsy
Powered by NewsLook.com
A Quick 45-Minute Nap Can Improve Your Memory

A Quick 45-Minute Nap Can Improve Your Memory

Newsy (Mar. 23, 2015) Researchers found those who napped for 45 minutes to an hour before being tested on information recalled it five times better than those who didn&apos;t. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins