Featured Research

from universities, journals, and other organizations

Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness

Date:
February 6, 2007
Source:
American Academy of Sleep Medicine
Summary:
A study published in the February 1st issue of the journal SLEEP provides a first direct demonstration that the "quality" and "intensity" of wakefulness can affect slow-wave activity during subsequent sleep.

A study published in the February 1st issue of the journal SLEEP provides a first direct demonstration that the "quality" and "intensity" of wakefulness can affect slow-wave activity (SWA) during subsequent sleep.

According to Chiara Cirelli, MD, PhD, of the University of Wisconsin-Madison, one of the authors of the study, the importance and novelty of the paper lies in the demonstration that the crucial factor linking physiological waking activity to sleep SWA is synaptic plasticity, notably synaptic potentiation, mediated by brain-derived neurotrophic factor (BDNF) signaling.

"Namely, the study shows that wakefulness associated with exposure to an enriched environment and with high levels of exploratory activity, a condition well known to trigger plastic changes in the brain, leads to increased BNDF expression and increased sleep pressure as compared to wakefulness with low exploratory activity," said Cirelli. "More stringently, the study finds that the amount of exploratory behavior during wakefulness can predict the extent to which BDNF is induced in the cerebral cortex, as well as the extent of the SWA response during subsequent sleep."

Cirelli notes that SWA has been validated as the best current marker of sleep pressure and sleep intensity by more than 30 years of research, and yet there is very poor understanding of the crucial factors that determine how and why sleep pressure increases during wakefulness and decreases during sleep.

"This paper offers a first hint of what may be at least one of the crucial factors linking the 'quality' of wakefulness to the intensity of sleep," added Cirelli.

The study is also novel in the approach used to prove this point, a combination of electroencephalographic, behavioral and molecular methods, said Cirelli, adding that the results of the study strongly support the hypothesis that synaptic plasticity during wakefulness is linked to sleep homeostasis. These findings complement other data recently published by Cirelli and her colleagues showing that the cortical areas more actively involved in the learning of a motor task during waking show the largest increase in SWA during subsequent sleep.

SLEEP is the official journal of the Associated Professional Sleep Societies, LLC, a joint venture of the American Academy of Sleep Medicine (AASM) and the Sleep Research Society.

SleepEducation.com, a Web site maintained by the AASM, provides information about the various sleep disorders that exist, the forms of treatment available, recent news on the topic of sleep, sleep studies that have been conducted and a listing of sleep facilities.


Story Source:

The above story is based on materials provided by American Academy of Sleep Medicine. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Sleep Medicine. "Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness." ScienceDaily. ScienceDaily, 6 February 2007. <www.sciencedaily.com/releases/2007/02/070201082510.htm>.
American Academy of Sleep Medicine. (2007, February 6). Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2007/02/070201082510.htm
American Academy of Sleep Medicine. "Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness." ScienceDaily. www.sciencedaily.com/releases/2007/02/070201082510.htm (accessed July 31, 2014).

Share This




More Mind & Brain News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dieting At A Young Age Might Lead To Harmful Health Habits

Dieting At A Young Age Might Lead To Harmful Health Habits

Newsy (July 30, 2014) Researchers say women who diet at a young age are at greater risk of developing harmful health habits, including eating disorders and alcohol abuse. Video provided by Newsy
Powered by NewsLook.com
It's Not Just Facebook: OKCupid Experiments With Users Too

It's Not Just Facebook: OKCupid Experiments With Users Too

Newsy (July 29, 2014) If you've been looking for love online, there's a chance somebody has been looking at how you're looking. Video provided by Newsy
Powered by NewsLook.com
How Your Face Can Leave A Good Or Bad First Impression

How Your Face Can Leave A Good Or Bad First Impression

Newsy (July 29, 2014) Researchers have found certain facial features can make us seem more attractive or trustworthy. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins