Featured Research

from universities, journals, and other organizations

Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness

Date:
February 6, 2007
Source:
American Academy of Sleep Medicine
Summary:
A study published in the February 1st issue of the journal SLEEP provides a first direct demonstration that the "quality" and "intensity" of wakefulness can affect slow-wave activity during subsequent sleep.

A study published in the February 1st issue of the journal SLEEP provides a first direct demonstration that the "quality" and "intensity" of wakefulness can affect slow-wave activity (SWA) during subsequent sleep.

According to Chiara Cirelli, MD, PhD, of the University of Wisconsin-Madison, one of the authors of the study, the importance and novelty of the paper lies in the demonstration that the crucial factor linking physiological waking activity to sleep SWA is synaptic plasticity, notably synaptic potentiation, mediated by brain-derived neurotrophic factor (BDNF) signaling.

"Namely, the study shows that wakefulness associated with exposure to an enriched environment and with high levels of exploratory activity, a condition well known to trigger plastic changes in the brain, leads to increased BNDF expression and increased sleep pressure as compared to wakefulness with low exploratory activity," said Cirelli. "More stringently, the study finds that the amount of exploratory behavior during wakefulness can predict the extent to which BDNF is induced in the cerebral cortex, as well as the extent of the SWA response during subsequent sleep."

Cirelli notes that SWA has been validated as the best current marker of sleep pressure and sleep intensity by more than 30 years of research, and yet there is very poor understanding of the crucial factors that determine how and why sleep pressure increases during wakefulness and decreases during sleep.

"This paper offers a first hint of what may be at least one of the crucial factors linking the 'quality' of wakefulness to the intensity of sleep," added Cirelli.

The study is also novel in the approach used to prove this point, a combination of electroencephalographic, behavioral and molecular methods, said Cirelli, adding that the results of the study strongly support the hypothesis that synaptic plasticity during wakefulness is linked to sleep homeostasis. These findings complement other data recently published by Cirelli and her colleagues showing that the cortical areas more actively involved in the learning of a motor task during waking show the largest increase in SWA during subsequent sleep.

SLEEP is the official journal of the Associated Professional Sleep Societies, LLC, a joint venture of the American Academy of Sleep Medicine (AASM) and the Sleep Research Society.

SleepEducation.com, a Web site maintained by the AASM, provides information about the various sleep disorders that exist, the forms of treatment available, recent news on the topic of sleep, sleep studies that have been conducted and a listing of sleep facilities.


Story Source:

The above story is based on materials provided by American Academy of Sleep Medicine. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Sleep Medicine. "Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness." ScienceDaily. ScienceDaily, 6 February 2007. <www.sciencedaily.com/releases/2007/02/070201082510.htm>.
American Academy of Sleep Medicine. (2007, February 6). Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2007/02/070201082510.htm
American Academy of Sleep Medicine. "Slow-wave Activity During Sleep Affected By Quality, Intensity Of Wakefulness." ScienceDaily. www.sciencedaily.com/releases/2007/02/070201082510.htm (accessed September 22, 2014).

Share This



More Mind & Brain News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Food Addiction Might Be Caused By PTSD

Food Addiction Might Be Caused By PTSD

Newsy (Sep. 18, 2014) New research shows that women who suffer from PTSD are three times more likely to develop a food addiction. Video provided by Newsy
Powered by NewsLook.com
Corporal Punishment on Decline, Debate Renews

Corporal Punishment on Decline, Debate Renews

AP (Sep. 16, 2014) Corporal punishment in the United States is on the decline, but there is renewed debate over its use after Minnesota Vikings running back Adrian Peterson was charged with child abuse. (Sept. 16) Video provided by AP
Powered by NewsLook.com
FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins