Featured Research

from universities, journals, and other organizations

New Vaccine Effective Against Deadly Viral Disease Affecting Swine

Date:
February 10, 2007
Source:
Kansas State University
Summary:
Researchers from Kansas State University's College of Veterinary Medicine have completed a study showing that a newly-developed vaccine is effective against a deadly viral disease that is affecting swine herds in Kansas.

Clinical signs of the disease in pigs include extreme and sudden weight loss, immune suppression, labored breathing, jaundice and diarrhea. More severe cases of the syndrome are characterized by skin lesions, neurological deterioration, kidney failure and eventually death. Swine producers with infected herds have experienced a death loss of 20 percent to 40 percent in finisher pigs, which are pigs between 10 weeks to 20 weeks of age.
Credit: Photo by Regis Lefebure / Courtesy of USDA-Agricultural Research Service

Researchers from Kansas State University's College of Veterinary Medicine have completed a study showing that a newly-developed vaccine is effective against a deadly viral disease that is affecting swine herds in Kansas.

Related Articles


The disease, most widely known as porcine circovirus associated disease, was first recognized in Kansas swine herds in November 2005. The disease complex is an immunosuppressive condition associated with porcine circovirus type 2 or PCV2.

Clinical signs of the disease in pigs include extreme and sudden weight loss, immune suppression, labored breathing, jaundice and diarrhea. More severe cases of the syndrome are characterized by skin lesions, neurological deterioration, kidney failure and eventually death. Swine producers with infected herds have experienced a death loss of 20 percent to 40 percent in finisher pigs, which are pigs between 10 weeks to 20 weeks of age. This has resulted in a devastating economic loss.

The researchers began a field trial in summer 2006, testing a vaccine in commercial development. The researchers, all from the department of diagnostic medicine and pathobiology, were Bob Rowland, Dick Hesse, Steve Dritz, Jerome Nietfeld and Kyle Horlen. The field trial, directed by Dritz and Horlen, was conducted on a family-owned swine farm in northeast Kansas and concluded in January with promising results.

The study showed a 50 percent reduction in mortality of vaccinated pigs compared to non-vaccinated pigs. Mortality was 7 percent for vaccinated pigs compared to 17 percent for non-vaccinated pigs. Vaccinated pigs also experienced an increase in growth. On average, they were 20 pounds heavier than non-vaccinated pigs of the same age.

"Results from this study suggest that the tested vaccine is effective in controlling the PCV2 associated disease in pigs," said Rowland, a virologist and associate professor of diagnostic medicine and pathobiology.

The researchers recommend producers who suspect their pigs are experiencing a porcine circovirus type 2 associated disease outbreak contact their veterinarian to confirm the diagnosis and then acquire the vaccine, which is now available commercially.

"We want to make it clear to swine producers that this vaccine licensed by the U.S. Department of Agriculture's Center for Veterinary Biologics is safe and effective," Rowland said.

Disease associated with porcine circovirus type 2 was first identified in Canada a decade ago and later appeared in Europe. It has become widespread and is in most pork producing areas of the United States. Reports from other countries confirm that it is also becoming prevalent throughout the world.

Steve Henry, a swine veterinarian from Abilene and an adjunct professor of diagnostic medicine and pathobiology at K-State, is working closely with the research team. Henry said that it remains a mystery how the circovirus spreads. He said outbreaks have occurred rapidly, yet randomly in swine operations with the highest levels of biosecurity protocol.

"It makes control strategies like quarantine practically irrelevant if the virus can bypass the barriers," Henry said. "This is not a classic outbreak, in which the initial occurrence is followed by the ripple effect, spreading out from a source point."

While the results of this clinically significant project are encouraging, there are many questions about this emerging disease still facing K-State scientists. A special fund has been established for donations to further immediate research on porcine circovirus associated disease.


Story Source:

The above story is based on materials provided by Kansas State University. Note: Materials may be edited for content and length.


Cite This Page:

Kansas State University. "New Vaccine Effective Against Deadly Viral Disease Affecting Swine." ScienceDaily. ScienceDaily, 10 February 2007. <www.sciencedaily.com/releases/2007/02/070208172601.htm>.
Kansas State University. (2007, February 10). New Vaccine Effective Against Deadly Viral Disease Affecting Swine. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2007/02/070208172601.htm
Kansas State University. "New Vaccine Effective Against Deadly Viral Disease Affecting Swine." ScienceDaily. www.sciencedaily.com/releases/2007/02/070208172601.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Navy Unveils Robot Fish

Navy Unveils Robot Fish

Reuters - Light News Video Online (Dec. 18, 2014) The U.S. Navy unveils an underwater device that mimics the movement of a fish. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
The Hottest Food Trends for 2015

The Hottest Food Trends for 2015

Buzz60 (Dec. 17, 2014) Urbanspoon predicts whicg food trends will dominate the culinary scene in 2015. Mara Montalbano (@maramontalbano) has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins