Featured Research

from universities, journals, and other organizations

Difficult Births In Obese Women Due To Uterus Failure

Date:
April 19, 2007
Source:
University of Liverpool
Summary:
Scientists have uncovered the reason why overweight women have more Caesarean sections -- they are at significant risk of their uterus contracting poorly in childbirth.

Liverpool scientists have uncovered the reason why overweight women have more Caesarean sections; they are at significant risk of their uterus contracting poorly in childbirth.

In a study of 4,000 pregnant women, researchers found that almost 1 in 5 overweight women had to undergo an emergency Caesarean Section birth because the muscles in their uterus failed. The research suggests obesity impairs the ability of the uterus to contract sufficiently in order to dilate the cervix and deliver the baby.

The team from the University of Liverpool's Physiology department found that obese women were 3.5 times more likely to require a Caesarean for slow labour than normal weight women.

Obese women who gave birth vaginally were also found to encounter other problems in child birth -- more than twice as many (6%) experienced excessive bleeding following delivery compared with normal weight women (3%). This blood loss was also attributed to poor uterine activity in the obese group. Heavy bleeding occurs when the uterus is unable to contract well enough to clamp off the blood vessels that are sheared following delivery of the placenta.

Professor Sue Wray commented: "Our research shows overweight women are at considerably higher risk of having to undergo an emergency Caesarean Section birth and find labour a more difficult experience than normal weight women. Interestingly, when we took uterus muscle samples from the overweight women and studied them in the lab they also performed poorly and contracted less well than matched samples from normal weight women".

The research team found that less calcium was able to enter the uterine cells of the obese women to support uterus muscles in contracting during labour.

Professor Wray explained: "We suspect one reason preventing sufficient levels of calcium entering the uterus muscles is the high levels of cholesterol in an obese woman's bloodstream. This could disrupt cell membranes and signalling pathways, including calcium entry. We will be investigating this further in future studies."

Dr Siobhan Quenby from the University of Liverpool's Obstetrics department commented: "In the meantime it is vital pre-pregnancy advice and counselling is available to women about the implications of weight on childbirth. Pregnancies among overweight women must be classified as high risk pregnancies and appropriate antenatal care should be provided so they receive the optimum care during maternity."

The research, funded by the Medical Research Council, has been published in the British Journal of Obstetrics and Gynaecology.


Story Source:

The above story is based on materials provided by University of Liverpool. Note: Materials may be edited for content and length.


Cite This Page:

University of Liverpool. "Difficult Births In Obese Women Due To Uterus Failure." ScienceDaily. ScienceDaily, 19 April 2007. <www.sciencedaily.com/releases/2007/04/070418095053.htm>.
University of Liverpool. (2007, April 19). Difficult Births In Obese Women Due To Uterus Failure. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2007/04/070418095053.htm
University of Liverpool. "Difficult Births In Obese Women Due To Uterus Failure." ScienceDaily. www.sciencedaily.com/releases/2007/04/070418095053.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins