Featured Research

from universities, journals, and other organizations

Nanotechnology May Be Used To Regenerate Tissues, Organs

Date:
May 7, 2007
Source:
Northwestern University
Summary:
Research at Northwestern University has shown that a combination of nanotechnology and biology may enable damaged tissues and organs to heal themselves. In a dramatic demonstration of what nanotechnology might achieve in regenerative medicine, paralyzed lab mice with spinal cord injuries have regained the ability to use their hind legs six weeks after a simple injection of a purpose-designed nanomaterial.

Materials scientist Samuel Stupp and his coworkers designed molecules with the capacity to self-assemble into nanofibers once injected into the body with a syringe. When the nanofibers form they can be immobilized in an area of tissue where it is necessary to activate some biological process.
Credit: Image courtesy of Northwestern University

Research at Northwestern University has shown that a combination of nanotechnology and biology may enable damaged tissues and organs to heal themselves.

In a recent presentation at the Woodrow Wilson International Center for Scholars in Washington DC, Samuel I. Stupp, board of trustees professor of materials science, chemistry, and medicine, and director of the Institute for BioNanotechnology in Medicine (IBNAM), reported on his work that suggests nanotechnology can be used to mobilize the body's own healing abilities to repair or regenerate tissues and organs. Stupp was the featured speaker at the launching of a new report NanoFrontiers: Visions for the Future of Nanotechnology from the Center's Project on Emerging Nanotechnologies. The project was co-sponsored by the Directors of the NIH and the NSF.

In a dramatic demonstration of what nanotechnology might achieve in regenerative medicine, paralyzed lab mice with spinal cord injuries have regained the ability to use their hind legs six weeks after a simple injection of a purpose-designed nanomaterial.

A video of Stupp discussing his groundbreaking research with collaborator John Kessler, M.D., Davee Professor of Stem Cell Biology and chair of the Davee Department of Neurology at Northwestern University Feinberg School of Medicine is available at http://www.nanotechproject.org/114.

"By injecting molecules that were designed to self-assemble into nanostructures in the spinal tissue, we have been able to rescue and regrow rapidly damaged neurons," Stupp said. The nanofibers -- thousands of times thinner than a human hair -- are the key to not only preventing the formation of harmful scar tissue which inhibits spinal cord healing, but to stimulating the body into regenerating lost or damaged cells."

Stupp and his coworkers designed molecules with the capacity to self-assemble into nanofibers once injected into the body with a syringe. When the nanofibers form they can be immobilized in an area of tissue where it is necessary to activate some biological process, for example saving damaged cells or regenerating needed differentiated cells from stem cells.

This same work also has implications for Parkinson's and Alzheimer's, both diseases in which key brain cells stop working properly.

Stupp also reported on the ongoing research with collaborators in Mexico and Canada, showing the impressive visual of mice recovering from the symptoms of Parkinson's disease after being exposed to the bioactive nanostructures developed in Stupp's laboratory at Northwestern University. He also reported on work with Jon Lomasney, associate professor of pathology at Northwestern, demonstrating the use of nanostructures and proteins to achieve recovery of heart function after an infarct.


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "Nanotechnology May Be Used To Regenerate Tissues, Organs." ScienceDaily. ScienceDaily, 7 May 2007. <www.sciencedaily.com/releases/2007/05/070503205701.htm>.
Northwestern University. (2007, May 7). Nanotechnology May Be Used To Regenerate Tissues, Organs. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2007/05/070503205701.htm
Northwestern University. "Nanotechnology May Be Used To Regenerate Tissues, Organs." ScienceDaily. www.sciencedaily.com/releases/2007/05/070503205701.htm (accessed September 21, 2014).

Share This



More Plants & Animals News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: San Diego Zoo Welcomes Cheetah Cubs

Raw: San Diego Zoo Welcomes Cheetah Cubs

AP (Sep. 20, 2014) The San Diego Zoo has welcomed two Cheetah cubs to its Safari Park. The nearly three-week-old female cubs are being hand fed and are receiving around the clock care. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Chocolate Museum Opens in Brussels

Chocolate Museum Opens in Brussels

AFP (Sep. 19, 2014) Considered a "national heritage" in Belgium, chocolate now has a new museum in Brussels. In a former chocolate factory, visitors to the permanent exhibition spaces, workshops and tastings can discover derivatives of the cocoa bean. Duration: 01:00 Video provided by AFP
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins