Featured Research

from universities, journals, and other organizations

Extremely Drug Resistant TB, A Growing Problem In India

Date:
May 22, 2007
Source:
American Thoracic Society
Summary:
Extremely drug resistant TB, or XDR-TB, is a serious problem in India, according to a new study. The study, the first in India to look at the prevalence of XDR-TB, found this type of TB accounts for 8% of multi-drug-resistant cases, compared with about 4% in the United States.

Extremely drug resistant TB, or XDR-TB, is a serious problem in India, according to a new study.  The study, the first in India to look at the prevalence of XDR-TB, found this type of TB accounts for 8% of multi-drug-resistant cases, compared with about 4% in the United States.

Related Articles


MDR-TB (multi-drug resistant TB) describes strains of tuberculosis that are resistant to at least the two first-line TB drugs, isoniazid and rifampicin. XDR-TB is MDR-TB that is also resistant to three or more of the six classes of second-line drugs. XDR-TB leaves patients (including many people living with HIV) virtually untreatable using currently available anti-TB drugs.

Recent findings from a survey conducted by the World Health Organization and the Centers for Disease Control and Prevention found that XDR-TB has been identified in all regions of the world but occurs most frequently in the countries of the former Soviet Union and in Asia.

Sushil Jain of the Hinduja National Hospital in Mumbai, India, and colleagues examined 3,904 lab samples at their hospital, and found that 1,274 were positive for Mycobacterium tuberculosis. Of these, 32% were found to be MDR-TB, out of which 8% were XDR-TB. Tuberculosis can infect many sites in the body but most commonly affects the lungs. All XDR-TB cases were in patients with pulmonary tuberculosis, or TB found in the lungs, which can be spread by coughing, sneezing, laughing or singing. Repeated exposure to someone with TB disease is generally necessary for infection to take place.

The death rate of XDR-TB patients in the study was 42%, which Dr. Jain calls "alarmingly high."

"An important finding was that the majority of patients with XDR-TB were of younger age group (their average age was 30 years), thus posing a major threat to our economically productive population," Dr. Jain notes. "Serious efforts are needed to tackle this deadly disease which may become a global emergency." Dr. Jain says that XDR-TB has long existed in India but has been under-recognized and under-treated. "Most labs in India are not equipped to perform drug susceptibility tests so exact prevalence is difficult to ascertain, and treatment in the absence of reliable sensitivity reports is difficult. Compounding the problem is the huge costs of treating these most difficult TB patients," he said.

The research was presented at the American Thoracic Society 2007 International Conference, on Monday, May 21. "High Prevalence of XDR TB from a Tertiary Care Hospital in India" (Session B98; Abstract # 1398)


Story Source:

The above story is based on materials provided by American Thoracic Society. Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society. "Extremely Drug Resistant TB, A Growing Problem In India." ScienceDaily. ScienceDaily, 22 May 2007. <www.sciencedaily.com/releases/2007/05/070521162221.htm>.
American Thoracic Society. (2007, May 22). Extremely Drug Resistant TB, A Growing Problem In India. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2007/05/070521162221.htm
American Thoracic Society. "Extremely Drug Resistant TB, A Growing Problem In India." ScienceDaily. www.sciencedaily.com/releases/2007/05/070521162221.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins