Featured Research

from universities, journals, and other organizations

Scientist Observes Brain Cell Development In 'Real Time'

Date:
May 29, 2007
Source:
The Hebrew University of Jerusalem
Summary:
For the first time ever, a researcher has succeeded in observing in vivo the generation of neurons in the brain of a mammal. The scientists used mouse models to study how neurons, or nerve cells, develop from an undifferentiated cellular sphere into a rich and complex cell.

Magnified photo shows division of neuron in vivo.
Credit: Hebrew University of Jerusalem

For the first time anywhere, a researcher at the Hebrew University of Jerusalem has succeeded in observing in vivo the generation of neurons in the brain of a mammal.

Dr. Adi Mizrahi of the Department of Neurobiology at the Alexander Silberman Institute of Life Sciences at the Hebrew University, used mouse models to study how neurons, or nerve cells, develop from an undifferentiated cellular sphere into a rich and complex cell. This has great significance for the future of brain research, said Dr. Mizrahi, since "the structural and functional complexity of nerve cells remains one of the biggest mysteries of neuroscience, and we now have a model to study this complexity directly."

Using special microscopic imaging techniques, combined with virus gene technology, Dr. Mizrahi was able to develop an experimental model to study development of neural dendrites in vivo. The dendrites are the string-like extensions of the neuron that spread out to reach other neurons and serve as the points of communication between the neurons.

The model employed by Dr. Mizrahi in his research was the newborn neuron population which develops into the olfactory bulb of adult mice, providing them with a sense of smell. The development and maintenance of newborn neurons in this area was assessed by time-lapse imaging over several days at different stages of development. Mizrahi revealed that dendritic formation is highly dynamic. Moreover, once incorporated into the network, adult-born neurons in the study also remained dynamic and capable of continuous change.

This method provides a mechanism for observing, for the first time in a mammal, how a neuron develops into a rich and complex cell and how, once developed, neurons are maintained in the highly active and changing environment of the brain.

As for further research that some day could lead to significant breakthroughs in treatment of neural disorders, Dr. Mizrahi noted that "there are only a few small areas in the brain which are capable of neurogenesis, and they hide secrets we want to reveal."

The results of Dr. Mizrahi's work appeared in the online edition of Nature Neuroscience.


Story Source:

The above story is based on materials provided by The Hebrew University of Jerusalem. Note: Materials may be edited for content and length.


Cite This Page:

The Hebrew University of Jerusalem. "Scientist Observes Brain Cell Development In 'Real Time'." ScienceDaily. ScienceDaily, 29 May 2007. <www.sciencedaily.com/releases/2007/05/070524092639.htm>.
The Hebrew University of Jerusalem. (2007, May 29). Scientist Observes Brain Cell Development In 'Real Time'. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2007/05/070524092639.htm
The Hebrew University of Jerusalem. "Scientist Observes Brain Cell Development In 'Real Time'." ScienceDaily. www.sciencedaily.com/releases/2007/05/070524092639.htm (accessed July 30, 2014).

Share This




More Mind & Brain News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

It's Not Just Facebook: OKCupid Experiments With Users Too

It's Not Just Facebook: OKCupid Experiments With Users Too

Newsy (July 29, 2014) If you've been looking for love online, there's a chance somebody has been looking at how you're looking. Video provided by Newsy
Powered by NewsLook.com
How Your Face Can Leave A Good Or Bad First Impression

How Your Face Can Leave A Good Or Bad First Impression

Newsy (July 29, 2014) Researchers have found certain facial features can make us seem more attractive or trustworthy. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com
University Quiz Implies Atheists Are Smarter Than Christians

University Quiz Implies Atheists Are Smarter Than Christians

Newsy (July 25, 2014) An online quiz from a required course at Ohio State is making waves for suggesting atheists are inherently smarter than Christians. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins