Featured Research

from universities, journals, and other organizations

Growth Factors And Environment Combine To Increase Brain Maturation

Date:
May 31, 2007
Source:
Public Library of Science
Summary:
A new study shows that growth factors and the environment combine to increase brain maturation. Recent studies have demonstrated that rodents' brains are sensitive to the influences of the environment and in particular that maturation of the visual system is accelerated in an enriched environment, where animals can explore new objects, engage in physical exercise and play. The aim of this new research was to clarify the molecular mechanisms that control this phenomenon.

A new study shows that growth factors and the environment combine to increase brain maturation. The study was conducted by Francesca Ciucci, Elena Putignano, Laura Baroncelli, Silvia Landi, Nicoletta Berardi and Lamberto Maffei, based at the Neurobiology Laboratory of Scuola Normale Superiore in Pisa.

Related Articles


Professor Maffei's research group is known for studies on the development and plasticity of the brain. Recent studies by this group have demonstrated that rodents' brains are sensitive to the influences of the environment and in particular that maturation of the visual system is accelerated in an enriched environment, where animals can explore new objects, engage in physical exercise and play. The aim of this research was to clarify the molecular mechanisms that control this phenomenon.

Specifically, in this study a molecular factor, called Insulin-like growth factor I (IGF-I), has been found to be capable of mediating the accelerated maturation of cortical development produced by enriched environment. The present work suggests that IGF-1 action in mediating the effects produced by environmental enrichment on visual system could be exerted through an accelerated maturation of inhibitory circuitry, the modulation of which has already been involved in cortical plasticity. IGF-I could influence the expression of other neurotrophins like NGF and BDNF, important for visual system plasticity. New studies could lead to a better understanding of the relationship between these molecules in the modulation of brain plasticity.

Citation: Ciucci F, Putignano E, Baroncelli L, Landi S, Berardi N, et al (2007) Insulin-Like Growth Factor 1 (IGF-1) Mediates the Effects of Enriched Environment (EE) on Visual Cortical Development. PLoS ONE 2(5): e475. doi:10.1371/journal.pone.0000475, http://www.plosone.org/doi/pone.0000475.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Growth Factors And Environment Combine To Increase Brain Maturation." ScienceDaily. ScienceDaily, 31 May 2007. <www.sciencedaily.com/releases/2007/05/070529201030.htm>.
Public Library of Science. (2007, May 31). Growth Factors And Environment Combine To Increase Brain Maturation. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2007/05/070529201030.htm
Public Library of Science. "Growth Factors And Environment Combine To Increase Brain Maturation." ScienceDaily. www.sciencedaily.com/releases/2007/05/070529201030.htm (accessed October 24, 2014).

Share This



More Mind & Brain News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Academic Scandal Shocks UNC

Academic Scandal Shocks UNC

AP (Oct. 23, 2014) A scandal involving bogus classes and inflated grades at the University of North Carolina was bigger than previously reported, a new investigation found. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Working Mother Getaway: Beaches Turks & Caicos

Working Mother Getaway: Beaches Turks & Caicos

Working Mother (Oct. 22, 2014) Feast your eyes on this gorgeous family-friendly resort. Video provided by Working Mother
Powered by NewsLook.com
What Your Favorite Color Says About You

What Your Favorite Color Says About You

Buzz60 (Oct. 22, 2014) We all have one color we love to wear, and believe it or not, your color preference may reveal some of your character traits. In celebration of National Color Day, Krystin Goodwin (@kyrstingoodwin) highlights what your favorite colors may say about you. Video provided by Buzz60
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins