Featured Research

from universities, journals, and other organizations

Obesity Associated With A Lower Risk Of Tuberculosis In Older Chinese Population

Date:
June 26, 2007
Source:
JAMA and Archives Journals
Summary:
Obese or overweight Chinese individuals age 65 and older have a lower risk of developing tuberculosis than those at a normal weight, according to a recent study.

Obese or overweight Chinese individuals age 65 and older have a lower risk of developing tuberculosis than those at a normal weight, according to a study in the June 25 issue of Archives of Internal Medicine.

"Tuberculosis is commonly associated with poverty and undernutrition in both developed and developing countries. In addition, obesity is an increasing problem that is associated with a wide range of chronic degenerative conditions, notably, diabetes mellitus, a well-reported predisposing factor for active tuberculosis," according to background information in the article. "Few studies have systematically examined the effect of obesity and overweight on tuberculosis, especially in Asian populations."

Chi C. Leung, M.B.B.S., Tuberculosis and Chest Service, Hong Kong, and colleagues, studied 42,116 individuals 65 years or older enrolled in 18 health centers for elderly patients in Hong Kong. The patients were followed up from three months after enrollment in 2000 until December 31, 2005. The body mass index (BMI) of each patient was measured at the beginning of the study. Those with a BMI of less than 18.5 were grouped as underweight, 18.5 to less than 23 as normal, 23 to less than 25 as at risk (for obesity), 25 to less than 30 as overweight, and 30 or higher as obese.

During the follow-up period, 477 cases of active tuberculosis were reported, 326 (68.3 percent) of which were confirmed using cultures of the bacteria involved. The average time between enrollment and notification of tuberculosis was 881 days. "There were 395 new cases (82.8 percent) and 82 retreatment cases (17.2 percent). Pulmonary [lung] involvement was found in 426 cases (89.3 percent) and extrapulmonary [outside the lung] involvement in 87 (18.2 percent), including 36 cases (7.5 percent) with both," the authors write.

Individuals who developed active tuberculosis were taller on average, but had a lower body weight and BMI (22.5 vs. 24.3) at the beginning of the study than those who did not. "BMI outside the range of 18.5 to 23 decreased the active tuberculosis risk by 23.5 percent of the observed level. Baseline BMI obesity at 25 or above was associated with a 30.1 percent decrease in risk, whereas BMI lower than 18.5 increased the risk by 6.6 percent," according to the authors. A higher average initial BMI was found in pulmonary-only cases than in extrapulmonary-only cases (22.3 vs. 24.1).

"Obesity is associated with a lower risk of active pulmonary tuberculosis in the older population of Hong Kong," the authors conclude. "The presence of such a strong but selective association across the whole spectrum of BMI could have major biological, clinical and/or epidemiological implications. Further studies are indicated to explore the underlying mechanisms, potential clinical utilities and possible epidemiological consequences."

Reference: Arch Intern Med. 2007;167:1297-1304.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Obesity Associated With A Lower Risk Of Tuberculosis In Older Chinese Population." ScienceDaily. ScienceDaily, 26 June 2007. <www.sciencedaily.com/releases/2007/06/070625193438.htm>.
JAMA and Archives Journals. (2007, June 26). Obesity Associated With A Lower Risk Of Tuberculosis In Older Chinese Population. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2007/06/070625193438.htm
JAMA and Archives Journals. "Obesity Associated With A Lower Risk Of Tuberculosis In Older Chinese Population." ScienceDaily. www.sciencedaily.com/releases/2007/06/070625193438.htm (accessed April 16, 2014).

Share This



More Health & Medicine News

Wednesday, April 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com
Cognitive Function: Is It All Downhill From Age 24?

Cognitive Function: Is It All Downhill From Age 24?

Newsy (Apr. 15, 2014) A new study out of Canada says cognitive motor performance begins deteriorating around age 24. Video provided by Newsy
Powered by NewsLook.com
How Mt. Everest Helped Scientists Research Diabetes

How Mt. Everest Helped Scientists Research Diabetes

Newsy (Apr. 15, 2014) British researchers were able to use Mount Everest's low altitudes to study insulin resistance. They hope to find ways to treat diabetes. Video provided by Newsy
Powered by NewsLook.com
Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Newsy (Apr. 14, 2014) Richard van As lost all fingers on his right hand in a woodworking accident. Now, he's used the incident to create a prosthetic to help hundreds. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins