Featured Research

from universities, journals, and other organizations

Adding Folic Acid To Bread Could Help In The Fight Against Depression

Date:
June 27, 2007
Source:
University of York
Summary:
A unique study has confirmed a link between depression and low levels of folate, a vitamin which comes from vegetables. Depression may soon become the second leading cause of disability worldwide. It affects between 5% and 10% of individuals and is the third most common reason for consultation in primary care.

A unique study by researchers at the University of York and Hull York Medical School has confirmed a link between depression and low levels of folate, a vitamin which comes from vegetables.

In research published in the July edition of the Journal of Epidemiology and Community Health, the York team led by Dr Simon Gilbody, concluded that there was a link between depression and low folate levels, following a review of 11 previous studies involving 15,315 participants.

Last month, the Food Standards Agency recommended to UK Health Ministers the introduction of mandatory fortification of either bread or flour with folic acid to prevent neural tube defects, which can result in miscarriage, neonatal death or lifelong disability. The York study suggests that the measure may also help in the fight against depression.

Dr Gilbody said: "Our study is unique in that for the first time all the relevant evidence in this controversial area has been brought together. Although the research does not prove that low folate causes depression, we can now be sure that the two are linked. Interestingly, there is also some trial evidence that suggests folic acid supplements can benefit people with depression. We recommend that large trials should be carried out to further test this suggestion."

Recent research from the same team published in the American Journal of Epidemiology has also proved that people with depression commonly have a gene that means that they process folate less efficiently. Folate is linked to the production of some of the 'feel good' chemicals in the brain, such as serotonin. The identification of this gene provides a plausible explanation as to why folic acid supplements may help people with depression.

Depression may soon become the second leading cause of disability worldwide. It affects between 5% and 10% of individuals and is the third most common reason for consultation in primary care.

Article: Gilbody S, Lightfoot T and Sheldon T. ‘Is low folate a risk factor for depression? A meta-analysis and exploration of heterogeneity’. Journal of Epidemiology and Community Health 2007; 61: 631-637.

Article: Gilbody S, Lewis S and Lightfoot T. ‘MTHFR polymorphisms and psychiatric disorders: a HuGE review’. American Journal of Epidemiology 2007; 165: 1-13.


Story Source:

The above story is based on materials provided by University of York. Note: Materials may be edited for content and length.


Cite This Page:

University of York. "Adding Folic Acid To Bread Could Help In The Fight Against Depression." ScienceDaily. ScienceDaily, 27 June 2007. <www.sciencedaily.com/releases/2007/06/070626115240.htm>.
University of York. (2007, June 27). Adding Folic Acid To Bread Could Help In The Fight Against Depression. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2007/06/070626115240.htm
University of York. "Adding Folic Acid To Bread Could Help In The Fight Against Depression." ScienceDaily. www.sciencedaily.com/releases/2007/06/070626115240.htm (accessed September 16, 2014).

Share This



More Mind & Brain News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
'Magic Mushrooms' Could Help Smokers Quit

'Magic Mushrooms' Could Help Smokers Quit

Newsy (Sep. 11, 2014) In a small study, researchers found that the majority of long-time smokers quit after taking psilocybin pills and undergoing therapy sessions. Video provided by Newsy
Powered by NewsLook.com
'Fat Shaming' Might Actually Cause Weight Gain

'Fat Shaming' Might Actually Cause Weight Gain

Newsy (Sep. 11, 2014) A study for University College London suggests obese people who are discriminated against gain more weight than those who are not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins