Featured Research

from universities, journals, and other organizations

How Would The Avian Influenza Virus Be Transmitted In Human Households?

Date:
July 27, 2007
Source:
PLoS Computational Biology
Summary:
Scientists have used data from a small but well-defined study of H7N7 avian influenza virus transmission in human households to estimate transmissibility in humans living in close contact.

Recent outbreaks of emerging diseases such as SARS and H5N1 avian influenza have underlined the fact that animal pathogens may acquire the ability to spread efficiently in humans -- but as yet have not.

Monitoring the transmissibility of pathogens from animals in humans is therefore key for early detection of epidemic spread, and for effective control. In a study published in PLoS Computational Biology, the authors from the Netherlands and the United Kingdom have used data from a small but well-defined study of H7N7 avian influenza virus transmission in human households to estimate this transmissibility in humans living in close contact.

Infection clusters in human households may arise from transmission from:

  1. animals
  2. humans who were infected by animals (primary human-to-human transmission), or
  3. humans who were infected by humans (secondary human-to-human transmission).

It is efficient secondary human-to-human transmission that is a prerequisite for pandemic spread.

In this paper, a method is developed of analyzing the extent of direct human-to-human transmission in a previous outbreak of a highly pathogenic H7N7 avian influenza virus in the Netherlands. There is evidence to show that secondary human-to-human transmission is indeed a plausible explanation for the Dutch infection data.

Based on the estimates of the within-household transmission, van Boven et al. concluded that less than half of the household infections could have been prevented with current antiviral drugs. It is important to continuously monitor the transmissibility of animal pathogens to and between humans. "Obviously, for public health it is vital that such emerging secondary human-to-human transmission in the human population is detected as quickly as possible", says van Boven. This paper provides a method of doing so, using data that are easily collected for most infectious diseases.

Reference: van Boven M, Koopmans M, Du Ry van Beest Holle M, Meijer A, Klinkenberg D, et al. (2007) Detecting emerging transmissibility of avian influenza virus in human households. PLoS Comput Biol 3(7): e145. doi:10.1371/journal.pcbi.0030145


Story Source:

The above story is based on materials provided by PLoS Computational Biology. Note: Materials may be edited for content and length.


Cite This Page:

PLoS Computational Biology. "How Would The Avian Influenza Virus Be Transmitted In Human Households?." ScienceDaily. ScienceDaily, 27 July 2007. <www.sciencedaily.com/releases/2007/07/070725093625.htm>.
PLoS Computational Biology. (2007, July 27). How Would The Avian Influenza Virus Be Transmitted In Human Households?. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2007/07/070725093625.htm
PLoS Computational Biology. "How Would The Avian Influenza Virus Be Transmitted In Human Households?." ScienceDaily. www.sciencedaily.com/releases/2007/07/070725093625.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins