Featured Research

from universities, journals, and other organizations

Determining The Quality Of Ginkgo

Date:
August 17, 2007
Source:
National Institute of Standards and Technology
Summary:
NIST has issued a suite of Standard Reference Materials for ginkgo biloba, one of the most popular dietary supplements in the marketplace. The new reference materials are designed to help researchers validate the accuracy of analytical methods for flavonoids and terpene lactones (plant constituents that may be associated with the perceived effectiveness of ginkgo) as well as toxic elements in ginkgo.

Ginkgo leaves.
Credit: NIST

The National Institute of Standards and Technology (NIST) has issued a suite of Standard Reference Materials (SRMs) for ginkgo biloba, one of the most popular dietary supplements in the marketplace, with annual worldwide sales estimated at $1 billion.

The NIST reference materials are designed to help researchers validate the accuracy of analytical methods for flavonoids and terpene lactones (plant constituents that may be associated with the perceived effectiveness of ginkgo) as well as toxic elements in ginkgo*. In addition to supporting measurements associated with clinical trials or verifying product label claims, the reference materials also can be used by dietary supplement manufacturers to improve product consistency.

The fruits and seeds of the female ginkgo are used for a variety of purposes in traditional Chinese medicine. In the West, dietary supplements are more commonly formulated from ginkgo leaves and standardized leaf extracts. They are used in the treatment of asthma, bronchitis, fatigue and tinnitus (ringing in the ears); for memory improvement and for the prevention and treatment of Alzheimer's disease, although these uses have not been backed by rigorous clinical trials.

Ginkgo biloba contains a family of chemical constituents known as ginkgolides which have been associated with reduced platelet aggregation. The National Institute of Health's (NIH) National Center for Complementary and Alternative Medicine (NCCAM) notes promising results in a number of areas, but says "larger, well-designed research studies are needed."

The new ginkgo reference materials include: SRM 3246 Ginkgo biloba (leaves); SRM 3247 Ginkgo biloba Extract; and SRM 3248 Ginkgo-Containing Tablets. In addition, the three ginkgo SRMs are available packaged together as SRM 3249. The reference materials come with certified values for five terpene lactones, three flavonoid aglycones and four potentially toxic trace elements (arsenic, cadmium, lead and mercury).

The goal of NIST's ongoing effort with dietary supplements such as ginkgo biloba is to provide tools to the dietary supplement industry and measurement communities that will lead to improved quality of dietary supplements and the studies of their efficacy, as well as to ultimately reduce public health risks that could potentially be associated with the use of these products.

Support for the development of the gingko-related SRMs was provided in part by the National Institutes of Health (NIH) Office of Dietary Supplements (ODS) and the Food and Drug Administration (FDA) Center for Drug Evaluation and Research (CDER).

* C.A. Rimmer, S.B. Howerton, K.E. Sharpless, L.C. Sander, S.E. Long, K.E. Murphy, B.J. Porter, K. Putzbach, M.S. Rearick, S.A. Wise, L.J. Wood, R. Zeisler, D.K. Hancock, J.H. Yen, J.M. Betz, A.N. Pho, L. Yang, C. Scriver, S. Willie, R. Sturgeon, B. Schaneberg, C. Nelson, J. Skamarack, M. Pan, K. Levanseler, D. Gray, E.H. Waysek, A. Blatter and E. Reich. Characterization of a suite of ginkgo-containing standard reference materials. Analytical and Bioanalytical Chemistry. Published online: 7 July 2007. DOI 10.1007/s00216-007-1398-5.


Story Source:

The above story is based on materials provided by National Institute of Standards and Technology. Note: Materials may be edited for content and length.


Cite This Page:

National Institute of Standards and Technology. "Determining The Quality Of Ginkgo." ScienceDaily. ScienceDaily, 17 August 2007. <www.sciencedaily.com/releases/2007/08/070816173250.htm>.
National Institute of Standards and Technology. (2007, August 17). Determining The Quality Of Ginkgo. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2007/08/070816173250.htm
National Institute of Standards and Technology. "Determining The Quality Of Ginkgo." ScienceDaily. www.sciencedaily.com/releases/2007/08/070816173250.htm (accessed September 30, 2014).

Share This



More Plants & Animals News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Earth Has Lost Half Its Vertebrate Wildlife Since 1970: WWF

Earth Has Lost Half Its Vertebrate Wildlife Since 1970: WWF

Newsy (Sep. 30, 2014) A new study published by the World Wide Fund for Nature found that more than half of the world's wildlife population has declined since 1970. Video provided by Newsy
Powered by NewsLook.com
Dolphins Might Use Earth's Magnetic Field As A GPS

Dolphins Might Use Earth's Magnetic Field As A GPS

Newsy (Sep. 30, 2014) A study released Monday suggests dolphins might be able to sense the Earth's magnetic field and possibly use it as a means of navigation. Video provided by Newsy
Powered by NewsLook.com
How To Battle Stink Bug Season

How To Battle Stink Bug Season

Newsy (Sep. 30, 2014) Homeowners in 33 states grapple with stink bugs moving indoors at this time of year. Here are a few tips to avoid stink bug infestations. Video provided by Newsy
Powered by NewsLook.com
California University Designs Sustainable Winery

California University Designs Sustainable Winery

Reuters - US Online Video (Sep. 27, 2014) Amid California's worst drought in decades, scientists at UC Davis design a sustainable winery that includes a water recycling system. Vanessa Johnston reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins