Featured Research

from universities, journals, and other organizations

Novel Insecticidal Toxins From Bacteria

Date:
September 7, 2007
Source:
Society for General Microbiology
Summary:
A light-emitting strain of bacteria and a nematode worm, which work together to prey on soil-dwelling insects, use insecticidal toxins to kill their insect hosts. Scientists are now investigating the potential role of these toxins in bacteria pathogenic to humans.

A light-emitting strain of bacteria and a nematode worm, which work together to prey on soil-dwelling insects, use insecticidal toxins to kill their insect hosts. Scientists speaking at the Society for General Microbiology's 161st Meeting are now investigating the potential role of these toxins in bacteria pathogenic to humans.

Related Articles


Speaker Michelle Hares, of the University of Exeter, studies insect-killing nematode worms which have symbiotic bacteria living in their guts. When the worm encounters insect prey, it burrows into the insect's body and regurgitates the bacteria. These bacteria, called Photorhabdus luminescens, then release toxins directly into the insect's bloodstream, rapidly killing it. The insect's flesh then provides food for the bacteria and in turn the bacteria are food for the nematode.

"Once inside an insect, caterpillar or larva, the bacteria release a mixture of toxins which kill the victim", says Michelle Hares of the University of Exeter's Cornwall Campus. "The toxins we identified are made up of three different proteins, and all three are needed to kill the insect". The Cornwall based scientists also discovered that the same genes needed to make these protein toxins are found in the Yersinia pestis bacteria which caused the bubonic plague, and in Yersinia pseudotuberculosis which causes thousands of cases of gastroenteritis today.

When the toxic proteins from both these human pathogenic bacteria were fed to tobacco hornworm caterpillars they had no effect, but when the same proteins were put on living cells from humans both Yersinia bacteria strains killed the cells.

"Our initial interest in this group of toxins, was centered around the hunt for novel insecticides, but our work now suggests they may also play an important role in the evolution of human and mammalian disease", says Michelle Hares. "Our findings suggest that insecticidal toxin complexes have been adapted by the Yersinia family of bacteria to attack mammalian cells. We are therefore currently investigating exactly how the toxin complexes elicit their response and how they are involved in the evolution of pathogenic disease in Yersinia".

Mrs Hares is presenting the poster 'Insecticidal Toxins of Photorhabdus luminescens and Yersinia' on September 5 2007 at the University of Edinburgh, UK.


Story Source:

The above story is based on materials provided by Society for General Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

Society for General Microbiology. "Novel Insecticidal Toxins From Bacteria." ScienceDaily. ScienceDaily, 7 September 2007. <www.sciencedaily.com/releases/2007/09/070905081600.htm>.
Society for General Microbiology. (2007, September 7). Novel Insecticidal Toxins From Bacteria. ScienceDaily. Retrieved October 26, 2014 from www.sciencedaily.com/releases/2007/09/070905081600.htm
Society for General Microbiology. "Novel Insecticidal Toxins From Bacteria." ScienceDaily. www.sciencedaily.com/releases/2007/09/070905081600.htm (accessed October 26, 2014).

Share This



More Plants & Animals News

Sunday, October 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Reuters - Innovations Video Online (Oct. 24, 2014) Miniature deep sea animals discovered off the Australian coast almost three decades ago are puzzling scientists, who say the organisms have proved impossible to categorise. Academics at the Natural History of Denmark have appealed to the world scientific community for help, saying that further information on Dendrogramma enigmatica and Dendrogramma discoides could answer key evolutionary questions. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Black Bear Cub Goes Sunday Shopping

Black Bear Cub Goes Sunday Shopping

Reuters - Light News Video Online (Oct. 23, 2014) Price check on honey? Bear cub startles Oregon drugstore shoppers. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Dances With Wolves in China's Wild West

Dances With Wolves in China's Wild West

AFP (Oct. 23, 2014) One man is on a mission to boost the population of wolves in China's violence-wracked far west. The animal - symbol of the Uighur minority there - is under threat with a massive human resettlement program in the region. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins