Featured Research

from universities, journals, and other organizations

Virus Implicated In Colony Collapse Disorder In Bees

Date:
September 6, 2007
Source:
Columbia University's Mailman School of Public Health
Summary:
Scientists have found a significant connection between the Israeli Acute Paralysis Virus (IAPV) and Colony Collapse Disorder (CCD) in honey bees. The findings, an important step in addressing the disorder that is decimating bee colonies across the country.

Honey bee worker carrying a parasitic Varroa mite.
Credit: Image courtesy of ARS/USDA Scott Bauer

A team led by scientists from the Columbia University Mailman School of Public Health, Pennsylvania State University, the USDA Agricultural Research Service, University of Arizona, and 454 Life Sciences has found a significant connection between the Israeli Acute Paralysis Virus (IAPV) and colony collapse disorder (CCD) in honey bees.

Related Articles


The findings, an important step in addressing the disorder that is decimating bee colonies across the country, are published in the journal Science.

In colony collapse disorder, honey bee colonies inexplicably lose all of their worker bees. CCD has resulted in a loss of 50-90% of colonies in beekeeping operations across the U.S. The consortium of scientists who have been studying the role of infection in this phenomenon includes Diana Cox-Foster, professor in the Department of Entomology at Pennsylvania State University, Ian Lipkin, director of the Center for Infection and Immunity at Columbia University Mailman School of Public Health, Jeffery Pettis, research leader of the ARS Bee Research Laboratory, and Nancy Moran, Professor at the University of Arizona, Tucson.

Ian Lipkin, MD, professor of Epidemiology, Neurology, and Pathology at Columbia, and his team at the Mailman School's Center for Infection and Immunity, together with a team at 454 Life Sciences, used revolutionary genetic technologies, to survey microflora of CCD hives, normal hives, and imported royal jelly. Candidate pathogens were screened for significance of association with CCD by examining samples collected by the USDA and Penn State from several sites over a period of three years.

Using the 454 Life Sciences high-throughput DNA sequencing platform, and analytical methods developed at Columbia, Dr. Lipkin's team searched for footprints of viruses, bacteria, fungi, and parasites in thousands of sequences. Candidates were further characterized by more detailed sequence analysis to ascertain their specificity for CCD and relationship to known and unknown pathogens.

IAPV, an unclassified dicistrovirus not previously reported in the U.S. that is transmitted by the varroa mite, and Kasmir bee virus were only found in CCD hives. The researchers report that IAPV was found in all four affected operations sampled, in two of four royal jelly samples, and in the Australian sample. KBV was present in three of four CCD operations, but not in the royal jelly. One organism was significantly correlated with CCD: finding IAPV in a bee sample correctly distinguished CCD from non-CCD status 96.1 percent of the time.

"This is a powerful new strategy for looking at outbreaks of infectious disease and finding cause. Dr. Cox-Foster recruited us into this project, making a persuasive case for applying our state-of-the-art methods for differential diagnosis of infectious disease in humans, to this challenge in agricultural epidemiology," said Dr. Lipkin. "The profound synergy within the group--bringing entomology, microbiology, and bioinformatics together--enabled us to work toward a solution to this extraordinarily complex problem."

This is the first report of IAPV in the United States. IAPV was first described in 2004 in Israel where infected bees presented with shivering wings, progressed to paralysis and then died just outside the hive. Importation to the U.S. of bees from Australia began in 2004, coinciding with early reports of unusual colony declines.

IAPV was found in non-CCD hives in some cases, which could reflect strain variation, co-infection, or the presence of other stressors, such as pesticides or poor nutrition. The varroa mite, for example, absent in Australia, immunosuppresses bees making them more susceptible to infection by other organisms, including viruses. Other stressors may include chemical pesticides used on plants pollinated by bees and in hives to control pests.

"Our results indicate that IAPV is a significant marker for CCD. This discovery may be helpful in identifying hives at risk for disease. The next step is to ascertain whether IAPV, alone or in concert with other factors, can induce CCD in healthy bees," added Dr. Lipkin.

Bees play an integral role in the world food supply, and are essential for the pollination of over 90 fruit and vegetable crops worldwide, with the economic value of these agricultural products placed at more than $14.6 billion in the U.S. In addition to agricultural crops, honey bees also pollinate many native plants within the ecosystem. Recently, the increased deaths in bee colonies due to CCD seriously threaten the ability of the bee industry to meet the pollination needs of fruit and vegetable producers in the U.S.


Story Source:

The above story is based on materials provided by Columbia University's Mailman School of Public Health. Note: Materials may be edited for content and length.


Cite This Page:

Columbia University's Mailman School of Public Health. "Virus Implicated In Colony Collapse Disorder In Bees." ScienceDaily. ScienceDaily, 6 September 2007. <www.sciencedaily.com/releases/2007/09/070906140803.htm>.
Columbia University's Mailman School of Public Health. (2007, September 6). Virus Implicated In Colony Collapse Disorder In Bees. ScienceDaily. Retrieved October 26, 2014 from www.sciencedaily.com/releases/2007/09/070906140803.htm
Columbia University's Mailman School of Public Health. "Virus Implicated In Colony Collapse Disorder In Bees." ScienceDaily. www.sciencedaily.com/releases/2007/09/070906140803.htm (accessed October 26, 2014).

Share This



More Plants & Animals News

Sunday, October 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Reuters - Innovations Video Online (Oct. 24, 2014) Miniature deep sea animals discovered off the Australian coast almost three decades ago are puzzling scientists, who say the organisms have proved impossible to categorise. Academics at the Natural History of Denmark have appealed to the world scientific community for help, saying that further information on Dendrogramma enigmatica and Dendrogramma discoides could answer key evolutionary questions. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Black Bear Cub Goes Sunday Shopping

Black Bear Cub Goes Sunday Shopping

Reuters - Light News Video Online (Oct. 23, 2014) Price check on honey? Bear cub startles Oregon drugstore shoppers. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Dances With Wolves in China's Wild West

Dances With Wolves in China's Wild West

AFP (Oct. 23, 2014) One man is on a mission to boost the population of wolves in China's violence-wracked far west. The animal - symbol of the Uighur minority there - is under threat with a massive human resettlement program in the region. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins