Featured Research

from universities, journals, and other organizations

Looping Genes May Hold A Key To Understanding Breast Cancer

Date:
April 11, 2008
Source:
University of Queensland
Summary:
Another piece of the puzzle that is breast cancer has been found. Researchers have discovered how a particular gene associated with breast cancer behaves, which may lead to better testing for the debilitating disease.

Another piece of the puzzle that is breast cancer has been found by University of Queensland researchers.

Dr Melissa Brown, from UQ's School of Molecular and Microbial Sciences, and her team have discovered how a particular gene associated with breast cancer behaves, which may lead to better testing for the debilitating disease.

Dr Brown and Dr Juliet French at UQ, together with their colleagues at The University of Oxford, studied the BRCA1 gene and found that it exists in a looped formation.

"Our studies suggest that BRCA1 looks a bit like a bow when the gene is switched off, and that part of this 'bow' disappears when the gene is switched on," Dr Brown said.

"Interestingly, the shape of the bow changes in different breast cancer cells, raising the possibility that this gene looping may contribute to the cancer process."

She said ongoing studies would identify the specific DNA sequences and DNA binding molecules involved in BRCA1 gene looping. "The status of these sequences in a larger cohort of breast cancer patients will also be determined," she said.

"This information may lead to more sensitive pre-symptomatic testing for breast cancer and the identification of new therapeutic targets."

The research was recently published in the scientific journal Proceedings of the National Academy of Sciences.


Story Source:

The above story is based on materials provided by University of Queensland. Note: Materials may be edited for content and length.


Cite This Page:

University of Queensland. "Looping Genes May Hold A Key To Understanding Breast Cancer." ScienceDaily. ScienceDaily, 11 April 2008. <www.sciencedaily.com/releases/2008/04/080409100453.htm>.
University of Queensland. (2008, April 11). Looping Genes May Hold A Key To Understanding Breast Cancer. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2008/04/080409100453.htm
University of Queensland. "Looping Genes May Hold A Key To Understanding Breast Cancer." ScienceDaily. www.sciencedaily.com/releases/2008/04/080409100453.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
'Cadaver Dog' Sniffs out Human Remains

'Cadaver Dog' Sniffs out Human Remains

AP (Oct. 21, 2014) Where's a body buried? Buster's nose can often tell you. He's a cadaver dog, specially trained to find human remains and increasingly being used by law enforcement and accepted in courts. These dogs are helping solve even decades-old mysteries. (Oct. 21) Video provided by AP
Powered by NewsLook.com
How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
How Detroit's Money Woes Led To U.N.-Condemned Water Cutoffs

How Detroit's Money Woes Led To U.N.-Condemned Water Cutoffs

Newsy (Oct. 20, 2014) The United Nations says water is a human right, but should it be free? Detroit has cut off water to residents who can't pay, and the U.N. isn't happy. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins