Featured Research

from universities, journals, and other organizations

Looping Genes May Hold A Key To Understanding Breast Cancer

Date:
April 11, 2008
Source:
University of Queensland
Summary:
Another piece of the puzzle that is breast cancer has been found. Researchers have discovered how a particular gene associated with breast cancer behaves, which may lead to better testing for the debilitating disease.

Another piece of the puzzle that is breast cancer has been found by University of Queensland researchers.

Dr Melissa Brown, from UQ's School of Molecular and Microbial Sciences, and her team have discovered how a particular gene associated with breast cancer behaves, which may lead to better testing for the debilitating disease.

Dr Brown and Dr Juliet French at UQ, together with their colleagues at The University of Oxford, studied the BRCA1 gene and found that it exists in a looped formation.

"Our studies suggest that BRCA1 looks a bit like a bow when the gene is switched off, and that part of this 'bow' disappears when the gene is switched on," Dr Brown said.

"Interestingly, the shape of the bow changes in different breast cancer cells, raising the possibility that this gene looping may contribute to the cancer process."

She said ongoing studies would identify the specific DNA sequences and DNA binding molecules involved in BRCA1 gene looping. "The status of these sequences in a larger cohort of breast cancer patients will also be determined," she said.

"This information may lead to more sensitive pre-symptomatic testing for breast cancer and the identification of new therapeutic targets."

The research was recently published in the scientific journal Proceedings of the National Academy of Sciences.


Story Source:

The above story is based on materials provided by University of Queensland. Note: Materials may be edited for content and length.


Cite This Page:

University of Queensland. "Looping Genes May Hold A Key To Understanding Breast Cancer." ScienceDaily. ScienceDaily, 11 April 2008. <www.sciencedaily.com/releases/2008/04/080409100453.htm>.
University of Queensland. (2008, April 11). Looping Genes May Hold A Key To Understanding Breast Cancer. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2008/04/080409100453.htm
University of Queensland. "Looping Genes May Hold A Key To Understanding Breast Cancer." ScienceDaily. www.sciencedaily.com/releases/2008/04/080409100453.htm (accessed September 16, 2014).

Share This



More Health & Medicine News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Study Links Male-Pattern Baldness To Prostate Cancer

Study Links Male-Pattern Baldness To Prostate Cancer

Newsy (Sep. 16, 2014) New findings suggest men with a certain type of baldness at age 45 are 39 percent more likely to develop aggressive prostate cancer. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins