Featured Research

from universities, journals, and other organizations

Identifying Abnormal Protein Levels In Diabetic Retinopathy

Date:
May 13, 2008
Source:
American Chemical Society
Summary:
Researchers in Massachusetts are reporting an advance in bridging huge gaps in medical knowledge about the biochemical changes that occur inside the eyes of individuals with diabetic retinopathy (DR) -- a leading cause of vision loss and blindness in adults. They report discovery of 37 proteins that were increased or decreased in the eyes of patients with DR compared to patients without the disease.

Researchers in Massachusetts are reporting an advance in bridging huge gaps in medical knowledge about the biochemical changes that occur inside the eyes of individuals with diabetic retinopathy (DR) -- a leading cause of vision loss and blindness in adults. They report discovery of 37 proteins that were increased or decreased in the eyes of patients with DR compared to patients without the disease.

Edward P. Feener and colleagues point out that DR is a complication of diabetes that affects the eyesight of millions of people. It involves damage to blood vessels in the retina, the light sensitive tissue in the back of the eye. Physicians know that vessels grow abnormally, swell, and leak in DR. However, they have little understanding of the biochemical changes underlying those damaging events.

The researchers studied eye fluid from individuals with and without DR who were undergoing eye surgery. They analyzed proteins in the vitreous, the gel-like material inside the eye between the retina and the lens. The study found 252 proteins in the fluid, including 37 proteins that showed changes that were associated with proliferative diabetic retinopathy, the most severe form of the disease. The study could lead to new insights into disease mechanisms and new treatments, the article states.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ben-Bo Gao, Xiaohong Chen, Nigel Timothy, Lloyd Paul Aiello, Edward P. Feener. Characterization of the Vitreous Proteome in Diabetes without Diabetic Retinopathy and Diabetes with Proliferative Diabetic Retinopathy. Journal of Proteome Research, 2008; 7 (6): 2516 DOI: 10.1021/pr800112g

Cite This Page:

American Chemical Society. "Identifying Abnormal Protein Levels In Diabetic Retinopathy." ScienceDaily. ScienceDaily, 13 May 2008. <www.sciencedaily.com/releases/2008/05/080512092214.htm>.
American Chemical Society. (2008, May 13). Identifying Abnormal Protein Levels In Diabetic Retinopathy. ScienceDaily. Retrieved April 17, 2014 from www.sciencedaily.com/releases/2008/05/080512092214.htm
American Chemical Society. "Identifying Abnormal Protein Levels In Diabetic Retinopathy." ScienceDaily. www.sciencedaily.com/releases/2008/05/080512092214.htm (accessed April 17, 2014).

Share This



More Health & Medicine News

Thursday, April 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins