Featured Research

from universities, journals, and other organizations

Circumcision Safe In Both HIV-infected And HIV-uninfected Men, Study Finds

Date:
June 4, 2008
Source:
Public Library of Science
Summary:
Adult circumcision is safe in HIV-infected men without advanced HIV disease, according to research in PLoS Medicine. Analyzing results of two clinical trials of circumcision in the rural Rakai district of Uganda, scientists found approximately a 3 percent rate of moderate or severe surgical complications -- primarily infections -- in both HIV-positive and HIV-negative men, when circumcision was performed under optimal conditions.

Adult circumcision is safe in HIV-infected men without advanced HIV disease, according to research published in PLoS Medicine.

Related Articles


Analyzing results of two clinical trials of circumcision in the rural Rakai district of Uganda, Ron Gray of the Bloomberg School of Public Health, Johns Hopkins University and colleagues found approximately a 3% rate of moderate or severe surgical complications -- primarily infections -- in both HIV-positive and HIV-negative men, when circumcision was performed under optimal conditions. Healing was slower in the HIV-infected men, however, and men who resumed sexual intercourse before complete wound healing were at higher risk of complications. Men with symptoms of HIV infection or low CD4 T-cell counts were not included in the study.

A separately reported analysis from one of these trials found that women partners are more likely to become HIV infected by HIV-positive men who resume sex prior to complete wound healing. Therefore, for protection of both men and their women partners, refraining from intercourse after circumcision is essential until the wound has completely healed, which may take 6 weeks or longer.

Three clinical trials have already shown that circumcision reduces the risk of becoming HIV infected by about 60% in HIV-negative African men, with infrequent side effects. However, the side effects in HIV-positive men have not been previously reported. Because this study found no increased risk of surgical complications in HIV-positive men who undergo circumcision, it should not be necessary to screen men who have no symptoms of HIV in future circumcision programs. Not requiring screening should reduce the complexity of implementing such programs and also reduce any stigma resulting from exclusion, making it likely that more men will be willing to be circumcised.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kigozi et al. The safety of adult male circumcision in HIV-infected and uninfected men in Rakai, Uganda. PLoS Medicine, 2008; 5 (6): e116 DOI: 10.1371/journal.pmed.0050116

Cite This Page:

Public Library of Science. "Circumcision Safe In Both HIV-infected And HIV-uninfected Men, Study Finds." ScienceDaily. ScienceDaily, 4 June 2008. <www.sciencedaily.com/releases/2008/06/080602214155.htm>.
Public Library of Science. (2008, June 4). Circumcision Safe In Both HIV-infected And HIV-uninfected Men, Study Finds. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2008/06/080602214155.htm
Public Library of Science. "Circumcision Safe In Both HIV-infected And HIV-uninfected Men, Study Finds." ScienceDaily. www.sciencedaily.com/releases/2008/06/080602214155.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins