Featured Research

from universities, journals, and other organizations

Potential Role Of Fish-based Fatty Acids In Resolving, Preventing Asthma

Date:
June 25, 2008
Source:
NIH/National Institute of Allergy and Infectious Diseases
Summary:
In an ongoing effort to determine the anti-inflammatory value of diets rich in some types of fish, scientists studying asthma and allergic reactions have found that a molecule produced by the body from omega-3 fatty acids helps resolve and prevent respiratory distress in laboratory mice. The research, supported by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, was led by a research team at Brigham and Women's Hospital and Harvard Medical School.

In an ongoing effort to determine the anti-inflammatory value of diets rich in some types of fish, scientists studying asthma and allergic reactions have found that a molecule produced by the body from omega-3 fatty acids helps resolve and prevent respiratory distress in laboratory mice.

The research, supported by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, was led by a research team at Brigham and Women's Hospital and Harvard Medical School.

Resolvin E1 (RvE1) is a metabolic product of an omega-3 fatty acid found in cold-water fish such as salmon, mackerel and anchovies. It is made by the body in response to the onset of inflammation.

This study identified RvE1 as having a key role in both dampening the development of airway inflammation and promoting its resolution in mice, in part by dampening innate immune signals that trigger inflammation. Other studies have indicated that increased levels of omega-3 fatty acids are associated with lower asthma prevalence in people, but the mechanisms to support that observation are poorly understood.

The new study provides scientists an opportunity to focus on the role of RvE1 as a potential therapeutic candidate.


Story Source:

The above story is based on materials provided by NIH/National Institute of Allergy and Infectious Diseases. Note: Materials may be edited for content and length.


Journal Reference:

  1. Haworth et al. Resolvin E1 regulates interleukin 23, interferon-γ and lipoxin A4 to promote the resolution of allergic airway inflammation. Nature Immunology, 2008; DOI: 10.1038/ni.1627

Cite This Page:

NIH/National Institute of Allergy and Infectious Diseases. "Potential Role Of Fish-based Fatty Acids In Resolving, Preventing Asthma." ScienceDaily. ScienceDaily, 25 June 2008. <www.sciencedaily.com/releases/2008/06/080623175332.htm>.
NIH/National Institute of Allergy and Infectious Diseases. (2008, June 25). Potential Role Of Fish-based Fatty Acids In Resolving, Preventing Asthma. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2008/06/080623175332.htm
NIH/National Institute of Allergy and Infectious Diseases. "Potential Role Of Fish-based Fatty Acids In Resolving, Preventing Asthma." ScienceDaily. www.sciencedaily.com/releases/2008/06/080623175332.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com
The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins