Featured Research

from universities, journals, and other organizations

Viruses Hitch A Ride In The Cell

Date:
June 26, 2008
Source:
Society for General Microbiology
Summary:
Viruses can travel around cells they infect by hitching a ride on a microscopic transport system, according to new research. Cells are exposed to foreign DNA and RNA and it is understood that some of this genetic material can be integrated into the host genome. Using modern microscopic techniques, scientists have been able to see how virus DNA is transported in the cell.

Viruses can travel around cells they infect by hitching a ride on a microscopic transport system, according to new research. Cells are exposed to foreign DNA and RNA and it is understood that some of this genetic material can be integrated into the host genome. Using modern microscopic techniques, scientists have been able to see how virus DNA is transported in the cell.

Related Articles


Professor Dr Urs Greber from the University of Zurich will describe interactions between viruses and the cell cytoskeleton on June 24 2008 at the new SGM-RMS satellite meeting, part of the MICROSCIENCE 2008 conference being held at the ExCeL conference centre in London.

"We have been using human adenoviruses (Ads) to investigate transport processes of foreign DNA in the cytoplasm of human cells," said Professor Dr Greber. "Adenoviruses are a diverse family of agents that replicate their DNA genome in the cell nucleus. We wanted to find out how the virus gets to the nucleus to replicate. To do this we have been using live cell fluorescence microscopy, which means we can literally watch the virus travelling inside the cell."

Human adenoviruses can cause respiratory, urinary and digestive infections. They occasionally cause epidemic conjunctivitis, and can be fatal in immunocompromised patients. Adenoviruses can aggravate asthmatic conditions, and are associated with deadly gastroenteritis in babies. This research improves our knowledge of how the virus replicates in host cells.

"Virus DNA is transported from the edge of the cell to the nucleus in the middle by attaching to microtubules. These are microscopic tubes that form part of the cytoskeleton, keeping the cell in shape and carrying molecules around in the cytoplasm," said Professor Dr Greber. "We found an unexpected new link between microtubule-based transport in the cytoplasm of the cell and the import of virus DNA to the nucleus."

Other talks at the one-day SGM meeting will concentrate on the 'tussle' that takes place when a host cell tries to fight back against an invading pathogen. Sir David King will start the day by talking about the 'Twenty first century challenges of sustainability and wellbeing'. Professor Timo Hyypia (University of Turku) will speak on 'Cellular interactions of enteroviruses' and Dr Mark Jepson (University of Bristol) will look at the way in which bacteria invade cells. The manipulation of cellular compartments by the SARS coronavirus for replication purposes will also be discussed by Dr Marjolein Kikkert (Leiden University Medical Centre).


Story Source:

The above story is based on materials provided by Society for General Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

Society for General Microbiology. "Viruses Hitch A Ride In The Cell." ScienceDaily. ScienceDaily, 26 June 2008. <www.sciencedaily.com/releases/2008/06/080624111015.htm>.
Society for General Microbiology. (2008, June 26). Viruses Hitch A Ride In The Cell. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2008/06/080624111015.htm
Society for General Microbiology. "Viruses Hitch A Ride In The Cell." ScienceDaily. www.sciencedaily.com/releases/2008/06/080624111015.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
New Fish Species Discovered, Setting Record for World's Deepest

New Fish Species Discovered, Setting Record for World's Deepest

Buzz60 (Dec. 22, 2014) A new species of fish is discovered living five miles beneath the ocean surface, making it the deepest living fish on earth. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins