Featured Research

from universities, journals, and other organizations

Bacterial Resistance Is Futile Against Wound-cleaning Laser

Date:
July 1, 2008
Source:
BioMed Central
Summary:
A laser-activated antimicrobial offers hope for new treatments of bacterial infections, even those that are resistant to current drugs. A new dye, indocyanine green, produces bacteria-killing chemicals when lit by a specific kind of laser light.

A laser-activated antimicrobial offers hope for new treatments of bacterial infections, even those that are resistant to current drugs. A new study describes the use of a dye, indocyanine green, which produces bacteria-killing chemicals when lit by a specific kind of laser light.

Michael Wilson led a team from UCL (University College London) who carried out experiments showing that activated indocyanine green is capable of killing a wide range of bacteria including Staphylococcus aureus, Streptococcus pyogenes and Pseudomonas aeruginosa. The dye is safe for humans. The strength of this new approach lies in the variety of ways in which the chemicals produced by the activated dye harm bacteria.

As Wilson explains, this means that resistance is unlikely to develop, "The mechanism of killing is non-specific, with reactive oxygen species causing damage to many bacterial components, so resistance is unlikely to develop - even from repeated use". Michael Wilson's co-authors on the study include Ghada Omar and Sean Nair of the Division of Microbial Diseases, UCL Eastman Dental Institute.

The increasing occurrence of bacterial resistance is a well-known problem facing modern medicine. The laser-powered treatment described in the study will be useful in the treatment of infections that occur in wounds.

According to Wilson "Infected wounds are responsible for significant morbidity and mortality, and an increase in the duration and the cost of hospital stay. The growing resistance to conventional antibiotics among organisms that infect wounds and burns makes such infections difficult to treat. The technique we are exploring is driven by the need to develop novel strategies to which pathogens will not easily develop resistance."

The laser used by the researchers emits 'near-infrared' light, which is known to be capable of producing heat. However, as Wilson describes, "Substantial killing of all of the bacteria tested was achieved without causing any temperature rise. The benefit of the laser described in this study is that it produces light that is more able to penetrate deep wounds, increasing the area cleansed".


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ghada S Omar, Michael Wilson and Sean P Nair. Lethal photosensitization of wound-associated microbes using indocyanine green and near-infrared light. BMC Microbiology, (in press)

Cite This Page:

BioMed Central. "Bacterial Resistance Is Futile Against Wound-cleaning Laser." ScienceDaily. ScienceDaily, 1 July 2008. <www.sciencedaily.com/releases/2008/06/080630200944.htm>.
BioMed Central. (2008, July 1). Bacterial Resistance Is Futile Against Wound-cleaning Laser. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2008/06/080630200944.htm
BioMed Central. "Bacterial Resistance Is Futile Against Wound-cleaning Laser." ScienceDaily. www.sciencedaily.com/releases/2008/06/080630200944.htm (accessed September 30, 2014).

Share This



More Matter & Energy News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Argentina's Tax Evaders Detected, Hunted Down by Drones

Argentina's Tax Evaders Detected, Hunted Down by Drones

AFP (Sep. 30, 2014) Argentina doesn't only have Lionel Messi the footballer, it has now also acquired "Mesi" the drone system which monitors undeclared mansions, swimming pools and soy fields to curb tax evasion in the country. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
Do Video Games Trump Brain Training For Cognitive Boosts?

Do Video Games Trump Brain Training For Cognitive Boosts?

Newsy (Sep. 29, 2014) More and more studies are showing positive benefits to playing video games, but the jury is still out on brain training programs. Video provided by Newsy
Powered by NewsLook.com
CERN Celebrates 60 Years of Science

CERN Celebrates 60 Years of Science

Reuters - Business Video Online (Sep. 29, 2014) CERN, the European Organisation for Nuclear Research, celebrates 60 years of bringing nations together through science. As Joanna Partridge reports from inside the famous science centre it's also planning to turn the Large Hadron Collider particle accelerator back on after an upgrade. Video provided by Reuters
Powered by NewsLook.com
This 'Invisibility Cloak' Is Simpler Than Most

This 'Invisibility Cloak' Is Simpler Than Most

Newsy (Sep. 28, 2014) Researchers from the University of Rochester have created a type of invisibility cloak with simple focal lenses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins