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Mercury Pollution Causes Immune Damage To Harbor Seals

Date:
October 24, 2008
Source:
Environmental Health
Summary:
Methylmercury, the predominant form of mercury found in the blood of marine mammals and fish-eating communities, could be more damaging to seals than has previously been thought. New research shows that MeHg harms T-lymphocytes, key cells in a seal's immune system. Similar results were also found for human lymphocytes.
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Harbor seal swimming.
Credit: iStockphoto/Andy Raatz

Methylmercury (MeHg), the predominant form of mercury found in the blood of marine mammals and fish-eating communities, could be more damaging to seals than has previously been thought. New research shows that MeHg harms T-lymphocytes, key cells in a seal's immune system. Similar results were also found for human lymphocytes.

Mercury exposure is known to occur as a result of man-made pollution and natural events such as volcanic eruptions.

According to the lead author of this study, Krishna Das of the Université de Liège, Belgium, "Mercury is known to bioaccumulate and to magnify in marine mammals, which is a cause of great concern in terms of their general health. In particular, the immune system is known to be susceptible to long-term mercury exposure". In order to determine the scale of this problem, the authors carried out analysis of the blood mercury levels of harbour seals caught in the North Sea and tested the effects of MeHg in lab experiments.

By applying increasing doses of MeHg to lymphocytes, a type of white blood cell, the authors determined that the amount of mercury found in the blood of the seals studied was enough to cause damage to the important immune system cells. They said, "Although the in vitro approach utilised in this investigation represents an extreme reductionism relative to the complex situation in the intact organism, it provides an insight into the specific effects of mercury pollution."

Immune system damage may already have taken a toll on the population of harbour seals. The 1998 and 2002 outbreaks of phocine distemper virus, known to have killed thousands of seals, were linked to the deleterious effects of pollution on the seals' ability to fight the infection.


Story Source:

The above post is reprinted from materials provided by Environmental Health. Note: Materials may be edited for content and length.


Journal Reference:

  1. Krishna Das, Ursula Siebert, Audrey Gillet, Aurélie Dupont, Carole Di-Poi, Sonja Fonfara, Gabriel Mazzucchelli, Edwin De Pauw and Marie-Claire De Pauw-Gillet. Mercury immune toxicity in harbour seals: links to in vitro toxicity. Environmental Health, (in press)

Cite This Page:

Environmental Health. "Mercury Pollution Causes Immune Damage To Harbor Seals." ScienceDaily. ScienceDaily, 24 October 2008. <www.sciencedaily.com/releases/2008/10/081020191532.htm>.
Environmental Health. (2008, October 24). Mercury Pollution Causes Immune Damage To Harbor Seals. ScienceDaily. Retrieved August 3, 2015 from www.sciencedaily.com/releases/2008/10/081020191532.htm
Environmental Health. "Mercury Pollution Causes Immune Damage To Harbor Seals." ScienceDaily. www.sciencedaily.com/releases/2008/10/081020191532.htm (accessed August 3, 2015).

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