Featured Research

from universities, journals, and other organizations

Wasabi Receptor Can Sense Ammonia That Causes Pain

Date:
November 14, 2008
Source:
National Institute for Physiological Sciences
Summary:
A Japanese research group has found that the receptor for hot taste of wasabi, Japanese horseradish usually eaten with sushi, can sense alkaline pH caused by a base such as ammonia.

A Japanese research group, led by Prof Makoto Tominaga of National Institute for Physiological Sciences in Japan, has found that the receptor for hot taste of wasabi, Japanese horseradish usually eaten with Sushi, can sense alkaline pH caused by base such as ammonia.

Related Articles


The team reports their finding in Journal of Clinical Investigation on November 13, 2008.

Clinically, alkaline pH is known to cause pain but the mechanism has been not known. By electrophysiological experiments, the team found that the WASABI receptor, namely transient receptor potential (TRP) A1 receptor, can be activated by alkalization inside of cells by application of base such as ammonia.

Administration of such base to the foot of mice caused transient pain-related behaviors. However, it did not in TRPA1 deficient mice.

"It has the first report showing molecular entity for the alkali-sensor. You could feel pain when you eat too much WASABI with Japanese Sushi. We found that this pain sensation is the same with that caused by ammonia", said Prof Tominaga.


Story Source:

The above story is based on materials provided by National Institute for Physiological Sciences. Note: Materials may be edited for content and length.


Cite This Page:

National Institute for Physiological Sciences. "Wasabi Receptor Can Sense Ammonia That Causes Pain." ScienceDaily. ScienceDaily, 14 November 2008. <www.sciencedaily.com/releases/2008/11/081113181209.htm>.
National Institute for Physiological Sciences. (2008, November 14). Wasabi Receptor Can Sense Ammonia That Causes Pain. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2008/11/081113181209.htm
National Institute for Physiological Sciences. "Wasabi Receptor Can Sense Ammonia That Causes Pain." ScienceDaily. www.sciencedaily.com/releases/2008/11/081113181209.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins