Featured Research

from universities, journals, and other organizations

Genetic Patterning In Fruit Fly Development Identified

Date:
December 11, 2008
Source:
Rutgers University
Summary:
No matter the species, from flies to humans, we all start the same: a single-cell fertilized egg that embarks on an incredible journey. The specifics of this journey are being uncovered by one biologist who is researching how from one cell a jumble of many are able to organize and communicate, allowing life to spring forth.

In this dorsal view of an egg chamber, the colors show expression patterns of genes regulated by the pathways being studied.
Credit: Developmental Cell; N. Yakoby; 11/11/08

No matter the species, from flies to humans, we all start the same: a single-cell fertilized egg that embarks on an incredible journey.  The specifics of this journey are being uncovered at Rutgers University-Camden, where a biologist is researching how from one cell a jumble of many are able to organize and communicate, allowing life to spring forth.

According to Nir Yakoby, a recently appointed assistant professor of biology at Rutgers–Camden, his work on cell communication is a lot like genetic play dough. His medium however is fruit flies, thousands and thousands of them from various genetic backgrounds.

Yakoby knows that manipulating certain genes in the fruit fly egg will result in very specific consequences in the development of its shell. 

“Most people work on one gene at a time, but we’re interested in gene networks,” explains Yakoby, who earned his undergraduate and doctoral degrees from Hebrew University in Israel.  “While riding on the new wave of biology, systems biology, we are still keeping the fundamentals of developmental biology by asking how many genes are expressed over time and space.”

After four years of post-doctoral research at the Lewis-Sigler Institute for Integrative Genomics at Princeton University, the Rutgers—Camden scholar is interested in how Drosophila cells communicate and create genetic patterning during its eggshell formation. To gain this knowledge, Yakoby has studied eggshells from a range of Drosophila species for insight on how variations of patterns could reflect how actual structures have evolved.

The new Developmental Cell article offers precise outcomes for the tens of genes and hundreds of patterns involved in four developmental stages of the fruit fly’s eggs.  As part of a research team, Yakoby developed an innovative new coding language to formally follow and manage the dynamics of hundreds of gene-patterns.  The team concentrated on the two main patterning pathways of the Drosophila egg development: bone morphogenetic protein and epidermal growth factor receptor.  Most developmental and other diseases, such as cancer, are associated with these universal pathways.


Story Source:

The above story is based on materials provided by Rutgers University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Nir Yakoby, Christopher A. Bristow, Danielle Gong, Xenia Schafer, Jessica Lembong, Jeremiah J. Zartman, Marc S. Halfon, Trudi Schόpbach, Stanislav Y. Shvartsman. A Combinatorial Code for Pattern Formation in Drosophila Oogenesis. Developmental Cell, 11 November 2008 (Vol. 15, Issue 5, pp. 725-737) DOI: 10.1016/j.devcel.2008.09.008

Cite This Page:

Rutgers University. "Genetic Patterning In Fruit Fly Development Identified." ScienceDaily. ScienceDaily, 11 December 2008. <www.sciencedaily.com/releases/2008/12/081202115719.htm>.
Rutgers University. (2008, December 11). Genetic Patterning In Fruit Fly Development Identified. ScienceDaily. Retrieved September 3, 2014 from www.sciencedaily.com/releases/2008/12/081202115719.htm
Rutgers University. "Genetic Patterning In Fruit Fly Development Identified." ScienceDaily. www.sciencedaily.com/releases/2008/12/081202115719.htm (accessed September 3, 2014).

Share This



More Plants & Animals News

Wednesday, September 3, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) — You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
Get A Mortgage, Receive A Cat — Only In Russia

Get A Mortgage, Receive A Cat — Only In Russia

Newsy (Sep. 2, 2014) — The incentive is in keeping with a Russian superstition that it's good luck for a cat to be the first to cross the threshold of a new home. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) — The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Sharks Off the Menu and on the Tourist Trail in Palau

Sharks Off the Menu and on the Tourist Trail in Palau

AFP (Sep. 2, 2014) — Tourists in Palau clamour to dive with sharks thanks to a pioneering conservation initiative -- as the island nation plans to completely ban commercial fishing in its vast ocean territory. 01:15 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins