Featured Research

from universities, journals, and other organizations

New Malaria Agent Found In Chimpanzees Close To That Commonly Observed In Humans

Date:
May 29, 2009
Source:
Public Library of Science
Summary:
Researchers based in Gabon and France report the discovery of a new malaria agent infecting chimpanzees in Central Africa. This new species, named Plasmodium gaboni, is a close relative of the most virulent human agent P. falciparum.

Researchers based in Gabon and France report the discovery of a new malaria agent infecting chimpanzees in Central Africa. This new species, named Plasmodium gaboni, is a close relative of the most virulent human agent P. falciparum.

The research is described in an article published May 29 in the open-access journal PLoS Pathogens.

P. falciparum is the major human malaria agent responsible for one to three million deaths annually. In 2002, the publication of the genome of P. falciparum generated new hopes in the fight against this deadly disease, by the opportunities it offered to discover new drug targets. However, the lack of known related genomes has limited the development of comparative genomics according to the study's researchers from Centre International de Recherches M้dicales de Franceville, Centre National de la Recherche Scientifique, and l'Institut de Recherche pour le D้veloppement.

To investigate the diversity of Plasmodium parasites circulating in chimpanzees in Africa, the team collected blood from 19 wild-borne animals kept as pets by villagers in Gabon. Two were found infected by a Plasmodium parasite. The sequencing of the parasite's whole mitochondrial genome revealed that it belonged to a previously undescribed species of Plasmodium, closely related to P. falciparum. Sequencing of the nuclear genome of this new agent should further the understanding of genomic adaptations of P. falciparum to humans and thus help discover new potential drug targets.

The development of comparative genomics to further understanding of P. falciparum has been hindered by a lack of knowledge of closely related species' genomes. Only one species, P. reichenowi, infecting chimpanzees, was previously known as a sister lineage of P. falciparum. Additional information on related species has thus been needed, making the discovery of P. gaboni an important step forward in exploring a possible relationship for malaria between chimpanzees and humans.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ollomo B, Durand P, Prugnolle F, Douzery E, Arnathau C, et al. A New Malaria Agent in African Hominids. PLoS Pathogens, 2009; 5 (5): e1000446 DOI: 10.1371/journal.ppat.1000446

Cite This Page:

Public Library of Science. "New Malaria Agent Found In Chimpanzees Close To That Commonly Observed In Humans." ScienceDaily. ScienceDaily, 29 May 2009. <www.sciencedaily.com/releases/2009/05/090528203735.htm>.
Public Library of Science. (2009, May 29). New Malaria Agent Found In Chimpanzees Close To That Commonly Observed In Humans. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2009/05/090528203735.htm
Public Library of Science. "New Malaria Agent Found In Chimpanzees Close To That Commonly Observed In Humans." ScienceDaily. www.sciencedaily.com/releases/2009/05/090528203735.htm (accessed April 23, 2014).

Share This



More Health & Medicine News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) — Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) — NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com
How to Master Motherhood With the Best Work/Life Balance

How to Master Motherhood With the Best Work/Life Balance

TheStreet (Apr. 22, 2014) — In the U.S., there are more than 11 million couples trying to conceive at any given time. From helping celebrity moms like Bethanny Frankel to ordinary soon-to-be-moms, TV personality and parenting expert, Rosie Pope, gives you the inside scoop on mastering motherhood. London-born entrepreneur Pope is the creative force behind Rosie Pope Maternity and MomPrep. She explains why being an entrepreneur offers the best life balance for her and tips for all types of moms. Video provided by TheStreet
Powered by NewsLook.com
Catching More Than Fish: Ugandan Town Crippled by AIDS

Catching More Than Fish: Ugandan Town Crippled by AIDS

AFP (Apr. 22, 2014) — The village of Kasensero on the shores of Lake Victoria was where HIV-AIDS was first discovered in Uganda. Its transient population of fishermen and sex workers means the nationwide programme to combat the virus has had little impact. Duration: 02:30 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins