Science News
from research organizations

New Genetic Material From Group B Streptococcus Identified

Date:
October 22, 2009
Source:
USDA/Agricultural Research Service
Summary:
Group B Streptococcus is a versatile pathogen that affects a variety of animals. Now studies are revealing new information about this pathogen.
Share:
       
FULL STORY

Agricultural Research Service aquatic pathologist Joyce Evans and technician Daniel Brougher have shed new light on how Group B Streptococcus pathogens are genetically related, including identifying a previously unknown serotype in fish.
Credit: Photo by Peggy Greb

Streptococcus agalactiae (also called Group B Streptococcus, or GBS) is a versatile pathogen that affects a variety of animals. Now studies by Agricultural Research Service (ARS) scientists and their university colleagues are revealing new information about this pathogen.

The symptoms of GBS vary from animal to animal. In cattle, GBS is associated with mastitis, a painful udder inflammation that costs the U.S. cattle industry about $2 billion annually. In farmed and wild fish, the bacteria can cause meningo-encephalitis, which is accompanied by swimming difficulty and hemorrhaging.

To learn more about the emergence and transmission of GBS, scientists with the ARS Aquatic Animal Health Research Unit in Auburn, Ala., and Chestertown, Md., compared GBS samples, or "isolates," collected from infected fish, dolphins, cattle and humans. The study was led by ARS aquatic pathologist Joyce Evans in Chestertown.

The scientists collected the genetic material from several fish species in the United States, Latin America and the Middle East; a bottlenose dolphin in Kuwait; humans and cattle in North America, and humans in Japan.

The scientists used a technique known as multilocus sequence typing (MLST) to examine similarities and differences between the genes of the GBS isolates. This was the first study to apply the technology to GBS isolates from aquatic animals.

During characterization of the GBS isolates, the scientists discovered a previously unknown serotype in fish isolates from Kuwait, Brazil, Israel and the United States. This particular serotype had been found in some cattle and human GBS isolates, although it had never before been observed in fish or dolphin GBS isolates.

Using MLST data, Evans and her colleagues also discovered five previously unknown sequence types that were genetically unrelated to any known GBS sequence types. These novel genetic, serotypic and phenotypic strains will be explored for genes, unique antigens or virulence factors that may be involved in inducing protective immunity, and therefore could be potential candidates for superior vaccine efficacy against GBS in cattle and fish.

This research was published in several scientific journals between 2006 and 2009, most recently in the November 2008 issue of the Journal of Medical Microbiology and the May 2009 issue of Emerging Infectious Diseases.


Story Source:

The above post is reprinted from materials provided by USDA/Agricultural Research Service. Note: Materials may be edited for content and length.


Cite This Page:

USDA/Agricultural Research Service. "New Genetic Material From Group B Streptococcus Identified." ScienceDaily. ScienceDaily, 22 October 2009. <www.sciencedaily.com/releases/2009/08/090830104316.htm>.
USDA/Agricultural Research Service. (2009, October 22). New Genetic Material From Group B Streptococcus Identified. ScienceDaily. Retrieved July 31, 2015 from www.sciencedaily.com/releases/2009/08/090830104316.htm
USDA/Agricultural Research Service. "New Genetic Material From Group B Streptococcus Identified." ScienceDaily. www.sciencedaily.com/releases/2009/08/090830104316.htm (accessed July 31, 2015).

Share This Page: