Featured Research

from universities, journals, and other organizations

Tuberculosis Treatment May Be Shortened

Date:
September 14, 2009
Source:
NWO (Netherlands Organization for Scientific Research)
Summary:
It may be possible to shorten the duration of treatment for tuberculosis. Due to the long duration of treatment, not every patient sees it through. Partly because of this, tuberculosis is one of the most lethal diseases in developing countries.

According to Dutch researcher Hanneke Later-Nijland, it may be possible to shorten the duration of treatment for tuberculosis. Due to the long duration of treatment, not every patient sees it through. Partly because of this, tuberculosis is one of the most lethal diseases in developing countries.

The research conducted by Hanneke Later-Nijland is helping to shorten the duration of treatment for tuberculosis. Later-Nijland studied different groups of Indonesian tuberculosis patients. She believes it may be possible to shorten the duration of treatment by increasing the dose of the important drug rifampicin. After increasing the dose, the concentration of the drug in the blood plasma was higher than expected.

In addition, the tuberculosis patients in Later-Nijland's study did not experience more or different adverse effects at an increased dose than at a standard dose. Therefore increasing the dose of rifampicin might make it possible to reduce the length of treatment for tuberculosis without additional consequences. Research involving larger groups of patients will be needed to confirm this conclusion.

Tuberculosis and diabetes

Later-Nijland also conducted research into the reduced effectiveness of treatment in tuberculosis patients who also have type 2 diabetes. Her research revealed that the concentration of rifampicin in the blood plasma of patients with type 2 diabetes was lower than in patients with tuberculosis alone but who were administered the same dose. Whether tuberculosis patients with type 2 diabetes would benefit from a higher dose of rifampicin is a subject for further research.

Hanneke Later-Nijland started her research in October 2004 at Radboud University Nijmegen Medical Centre. She carried out her research within the Indonesian, Tanzanian and Dutch research network Poverty Related Infection Oriented Research, or PRIOR. PRIOR focused on research into poverty-related infectious diseases such as tuberculosis, HIV and malaria, and was funded by NWO.


Story Source:

The above story is based on materials provided by NWO (Netherlands Organization for Scientific Research). Note: Materials may be edited for content and length.


Cite This Page:

NWO (Netherlands Organization for Scientific Research). "Tuberculosis Treatment May Be Shortened." ScienceDaily. ScienceDaily, 14 September 2009. <www.sciencedaily.com/releases/2009/09/090902122523.htm>.
NWO (Netherlands Organization for Scientific Research). (2009, September 14). Tuberculosis Treatment May Be Shortened. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2009/09/090902122523.htm
NWO (Netherlands Organization for Scientific Research). "Tuberculosis Treatment May Be Shortened." ScienceDaily. www.sciencedaily.com/releases/2009/09/090902122523.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Nigeria Ups Ebola Stakes on 1st Death

Nigeria Ups Ebola Stakes on 1st Death

Reuters - Business Video Online (July 29, 2014) Nigerian authorities have shut and quarantined a Lagos hospital where a Liberian man died of the Ebola virus, the first recorded case of the highly-infectious disease in Africa's most populous economy. David Pollard reports Video provided by Reuters
Powered by NewsLook.com
Running 5 Minutes A Day Might Add Years To Your Life

Running 5 Minutes A Day Might Add Years To Your Life

Newsy (July 29, 2014) According to a new study, just five minutes of running or jogging a day could add years to your life. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Poses Little Threat To U.S.: CDC

Ebola Outbreak Poses Little Threat To U.S.: CDC

Newsy (July 29, 2014) The Ebola outbreak in West Africa poses little threat to Americans, according to officials with the Centers for Disease Control and Prevention. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins