Featured Research

from universities, journals, and other organizations

Genes Identified May Help Breast Cancer Diagnosis

Date:
September 12, 2009
Source:
Keele University
Summary:
Researchers have identified two genes which may help improve the diagnosis and treatment of breast cancer patients. They found that the survival rate for patients with a low expression of a gene known as Fau, a tumour suppressor, is twice as bad as for people with normal levels, while a high expression of cancer-causing gene MELK has a similar effect.

Researchers at Keele University have identified two genes which may help improve the diagnosis and treatment of breast cancer patients.

The research team, which also included colleagues from Nottingham and Cambridge universities and King’s College London, are identifying and studying genes which control whether a cell lives or dies.

They found that the survival rate for patients with a low expression of a gene known as Fau, a tumour suppressor, is twice as bad as for people with normal levels, while a high expression of cancer-causing gene MELK has a similar effect.

Professor Gwyn Williams, who has been working on the study for 20 years, said he was excited by the discovery, published in the journal Breast Cancer Research, as it had clear real world relevance.

“Our ongoing research is about finding the genes which may go wrong in people with cancer,” he said. “Genetic changes give hints to where to target therapy and can also help diagnose cancer.”

“When you know enough about genes like these you could carry out a general screening of people who might be at risk. This is not an overnight solution but in the next 20 years I would like to see our knowledge of Fau and MELK being used in more practical areas.”

Research teams will now study the two genes in greater depth to identify their uses in diagnosis. The findings may also prove significant in ovarian and prostate cancer research.


Story Source:

The above story is based on materials provided by Keele University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Pickard et al. Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer. Breast Cancer Research, 2009; 11 (4): R60 DOI: 10.1186/bcr2350

Cite This Page:

Keele University. "Genes Identified May Help Breast Cancer Diagnosis." ScienceDaily. ScienceDaily, 12 September 2009. <www.sciencedaily.com/releases/2009/09/090910121852.htm>.
Keele University. (2009, September 12). Genes Identified May Help Breast Cancer Diagnosis. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2009/09/090910121852.htm
Keele University. "Genes Identified May Help Breast Cancer Diagnosis." ScienceDaily. www.sciencedaily.com/releases/2009/09/090910121852.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Newsy (July 30, 2014) The Peace Corps is one of several U.S.-based organizations to pull workers out of West Africa because of the Ebola outbreak. Video provided by Newsy
Powered by NewsLook.com
Weather Kills 2K A Year, But Storms Aren't The Main Offender

Weather Kills 2K A Year, But Storms Aren't The Main Offender

Newsy (July 30, 2014) Health officials say 2,000 deaths occur each year in the U.S. due to weather, but it's excessive heat and cold that claim the most lives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins