Featured Research

from universities, journals, and other organizations

New clues emerge for understanding morphine addiction

Date:
December 27, 2009
Source:
American Chemical Society
Summary:
Scientists are adding additional brush strokes to the revolutionary new image now emerging for star-shaped cells called astrocytes in the brain and spinal cord. Their report suggests a key role for astrocytes in morphine's ability to relieve pain and cause addiction.

Scientists are reporting new clues to understanding morphine addiction.
Credit: US Drug Enforcement Administration

Scientists are adding additional brush strokes to the revolutionary new image now emerging for star-shaped cells called astrocytes in the brain and spinal cord. Their report, which suggests a key role for astrocytes in morphine's ability to relieve pain and cause addiction, appears online in ACS' Journal of Proteome Research, a monthly publication.

In the study, Piotr Suder and colleagues point out that nearly everyone viewed astrocytes -- the most abundant cells in the brain -- as supporting actors in the drama of brain activity. Scientists thought astrocytes simply propped up neurons, nerve cells that transmit signals, and kept them in proper position. Studies during the last several years, however, suggest that these cells are just as their Greek name suggests -- stars.

The scientists added morphine to a group of astrocytes in cell culture for several days. They found that the morphine-exposed cells showed increased levels of nine proteins that appear to play a role in maintaining the normal function of nerve cells.

"These proteins, after additional detailed study of their function, may serve as a potential marker of drug addiction, or may be the targets for potential therapy," the article notes.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Piotr Suder, Anna Bodzon-Kulakowska, Pawel Mak, Anna Bierczynska-Krzysik, Michal Daszykowski, Beata Walczak, Gert Lubec, Jolanta H. Kotlinska, Jerzy Silberring. The Proteomic Analysis of Primary Cortical Astrocyte Cell Culture after Morphine Administration. Journal of Proteome Research, 2009; 8 (10): 4633-4640 DOI: 10.1021/pr900443r

Cite This Page:

American Chemical Society. "New clues emerge for understanding morphine addiction." ScienceDaily. ScienceDaily, 27 December 2009. <www.sciencedaily.com/releases/2009/12/091209134902.htm>.
American Chemical Society. (2009, December 27). New clues emerge for understanding morphine addiction. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/2009/12/091209134902.htm
American Chemical Society. "New clues emerge for understanding morphine addiction." ScienceDaily. www.sciencedaily.com/releases/2009/12/091209134902.htm (accessed April 21, 2014).

Share This



More Health & Medicine News

Monday, April 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Breakfast Foods Are Getting Pricier

Breakfast Foods Are Getting Pricier

AP (Apr. 21, 2014) Breakfast is now being served with a side of sticker shock. The cost of morning staples like bacon, coffee and orange juice is on the rise because of global supply problems. (April 21) Video provided by AP
Powered by NewsLook.com
Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins