Featured Research

from universities, journals, and other organizations

Formula for making teeth will soon be found, researchers say

Date:
March 16, 2010
Source:
University of Helsinki
Summary:
Each cusp of our teeth is regulated by genes which carefully control the development. A similar genetic puzzle also regulates the differentiation of our other organs and of all living organisms. Scientists have developed a computer model reproducing population-level variation in complex structures like teeth and organs. The research takes a step towards the growing of correctly shaped teeth and other organs.

Each cusp of our teeth is regulated by genes which carefully control the development. A similar genetic puzzle also regulates the differentiation of our other organs and of all living organisms. A team of researchers at the Institute of Biotechnology of the University of Helsinki has developed a computer model reproducing population-level variation in complex structures like teeth and organs. The research takes a step towards the growing of correctly shaped teeth and other organs.

Related Articles


The results were published in Nature.

Academy Professor Jukka Jernvall and his team investigate the evolutionary development of mammal teeth. After over 15 years of work, the team has compiled so much data that the main aspects of a formula for making teeth are beginning to be clear. The model shows that regulation of tooth development is already well known. Teeth are a kind of "model species" for Jernvall's team, which means that the study results also tell about the development of other organs.

A mathematical model applied to the teeth of ringed seals

According to a mathematical computer model, a rather simple basic formula seems to be behind the complex gene puzzle resulting in tooth formations; the jungle of gene networks has a 'patterning kernel' regulating the variation of teeth among individuals in the same population. Also the variation of human teeth from the incisors to the molar teeth may result from a single factor regulating cell division.

The researchers tested their theoretical model, which is based on mouse tooth development, by investigating seal teeth. The Ladoga ringed seal collection of the Finnish Museum of Natural History at the University of Helsinki provided an ideal population sample for the research because dentitions are highly variable.

New teeth and organs?

The mathematical model proposed by the research team may give new kind of understanding on the formation of organisms' three-dimensional shapes: How do different levels of ontogeny function together? What factors guide the emergence of specific external features? The new research results may promote medical research, such as growing new organs.


Story Source:

The above story is based on materials provided by University of Helsinki. Note: Materials may be edited for content and length.


Journal Reference:

  1. Isaac Salazar-Ciudad, Jukka Jernvall. A computational model of teeth and the developmental origins of morphological variation. Nature, 2010; DOI: 10.1038/nature08838

Cite This Page:

University of Helsinki. "Formula for making teeth will soon be found, researchers say." ScienceDaily. ScienceDaily, 16 March 2010. <www.sciencedaily.com/releases/2010/03/100315103940.htm>.
University of Helsinki. (2010, March 16). Formula for making teeth will soon be found, researchers say. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2010/03/100315103940.htm
University of Helsinki. "Formula for making teeth will soon be found, researchers say." ScienceDaily. www.sciencedaily.com/releases/2010/03/100315103940.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins