Featured Research

from universities, journals, and other organizations

Oral bacteria linked to intrauterine infections and pre-term birth

Date:
April 15, 2010
Source:
American Society for Microbiology
Summary:
Bacteria in the mouths of pregnant women can contribute to pre-term birth, according to researchers.

Bacteria in the mouths of pregnant women can contribute to pre-term birth, according to researchers from Case Western Reserve University, Cleveland, Ohio, and Hathaway Brown School, Shaker Heights. The findings are published in the April 2010 issue of the journal Infection and Immunity.

Related Articles


Approximately 12.7% of births in the U.S. are pre-term deliveries, a rate that reflects a 36% increase over the last 25 years. Intrauterine infection is recognized as a main cause of pre-term birth as well as late miscarriage and still birth. The cause of intrauterine infections has long been attributed to bacteria ascending into the uterus from the lower genital tract, however, recent studies indicate such infections are caused not only by bacteria found in the vaginal tract, but also in the mouth.

The human mouth is home to approximately 700 bacterial species. Gingivitis, a common problem associated with pregnancy, increases bacterial concentrations in the mouth further enhancing the possibility of transmission to the placenta through the blood stream. In the study saliva and plaque samples were injected into the tails of pregnant mice to determine what bacteria are capable of oral-uterus transmission. Researchers identified a diverse group of bacterial species colonizing the mouse placenta, of which the majority originate in the oral cavity and are associated with adverse pregnancy outcomes in humans.

"This study provides the first insight into the diversity of oral bacteria associated with intrauterine infection," say the researchers. "Based on our findings, we postulate that periodontal therapies targeted at consistently reducing the total bacterial load in the mother's oral cavity may be effective in improving birth outcomes."


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Y. Fardini, P. Chung, R. Dumm, N. Joshi, Y.W. Han. Transmission of Diverse Oral Bacteria to Murine Placenta: Evidence for the Oral Microbiome as a Potential Source of Intrauterine Infection. Infection and Immunity, 2010; 78 (4): 1789 DOI: 10.1128/IAI.01395-09

Cite This Page:

American Society for Microbiology. "Oral bacteria linked to intrauterine infections and pre-term birth." ScienceDaily. ScienceDaily, 15 April 2010. <www.sciencedaily.com/releases/2010/04/100415134334.htm>.
American Society for Microbiology. (2010, April 15). Oral bacteria linked to intrauterine infections and pre-term birth. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2010/04/100415134334.htm
American Society for Microbiology. "Oral bacteria linked to intrauterine infections and pre-term birth." ScienceDaily. www.sciencedaily.com/releases/2010/04/100415134334.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins