Featured Research

from universities, journals, and other organizations

Majority of fevers in African children are not caused by malaria, study finds

Date:
July 12, 2010
Source:
Public Library of Science
Summary:
In 2007, an estimated 656 million fevers occurred in African children aged 0-4 years, with 78 million children of the 183 million attending a public health care facility likely to have been infected with P. falciparum (range 60-103 million), the parasite that causes the most dangerous form of malaria. These findings come from a modelling system devised by experts from the Malaria Atlas Project.

In 2007, an estimated 656 million fevers occurred in African children aged 0-4 years, with 78 million children of the 183 million attending a public health care facility likely to have been infected with P. falciparum (range 60-103 million), the parasite that causes the most dangerous form of malaria. These findings come from a modelling system devised by Peter Gething and colleagues from the Malaria Atlas Project, a multinational team of researchers funded mainly by the Wellcome Trust.

Related Articles


These findings, published in PLoS Medicine, are important given international efforts to increase the coverage of artemisinin-based combination therapy (ACT) in public health sectors and the mounting concern that the continued indiscriminate presumptive use of ACT for treating all childhood fevers may lead to resistance to one of the main drug classes currently effective in the treatment of falciparum malaria.

The authors were able to quantify the number of children with fevers who do and do not have malaria by gathering data on paediatric fever prevalence, treatment-seeking rates, and childhood populations and combining this information with a geographical information system model. The authors then assembled data to estimate plausible ranges for the proportion of paediatric fevers seen at clinics positive for P. falciparum in different malaria endemic areas.

This study provides a useful map of the prevalence of malarial and non-malarial childhood fevers across sub-Saharan Africa and an indication of how many of the children with fever reaching public clinics are likely to have malaria and might therefore benefit from ACT. Furthermore, these findings also highlight the potential benefits of introducing rapid diagnostic testing for malaria and can now be used to quantify the resources needed for and the potential clinical benefits of different policies for the introduction of rapid diagnostic testing for malaria across Africa.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Gething PW, Kirui VC, Alegana VA, Okiro EA, Noor AM, et al. Estimating the Number of Paediatric Fevers Associated with Malaria Infection Presenting to Africa's Public Health Sector in 2007. PLoS Med, 2010; 7(7): e1000301 DOI: 10.1371/journal.pmed.1000301

Cite This Page:

Public Library of Science. "Majority of fevers in African children are not caused by malaria, study finds." ScienceDaily. ScienceDaily, 12 July 2010. <www.sciencedaily.com/releases/2010/07/100706171123.htm>.
Public Library of Science. (2010, July 12). Majority of fevers in African children are not caused by malaria, study finds. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2010/07/100706171123.htm
Public Library of Science. "Majority of fevers in African children are not caused by malaria, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/07/100706171123.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins