Featured Research

from universities, journals, and other organizations

Two types of bone marrow stem cells could work together to advance regenerative medicine

Date:
August 17, 2010
Source:
Albert Einstein College of Medicine
Summary:
A unique "partnership" between two types of bone marrow stem cells could lead to advances in regenerative medicine.

A study led by a researcher at Albert Einstein College of Medicine of Yeshiva University has revealed a unique "partnership" between two types of bone marrow stem cells, which could lead to advances in regenerative medicine. The aim of regenerative medicine is to enable the body to repair, replace, restore or regenerate damaged or diseased cells, tissues and organs.

Related Articles


The study was led by Paul Frenette, M.D., the new director of the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Einstein. Dr. Frenette conducted the research while at Mt. Sinai School of Medicine in New York City.

Hematopoietic stem cells (HSCs) in the bone marrow perform the vital task of producing all blood cells in the human body. Now, the new study, published in the August 12 issue of Nature, has revealed that HSCs pair up in the bone marrow with another type of stem cells, known as mesenchymal stem cells, which give rise to bone, cartilage, fat and other tissues. This pairing, the research shows, form a unique stem cell "partnership" that could lead to advances in regenerative medicine.

The identity of cells in close proximity to HSCs had been a matter of dispute. Dr. Frenette and his team not only found that HSCs and mesenchymal stem cells partner physically with each other, but they also showed that the two types of stem cells interact in crucially important ways. Mesenchymal cells, for example, were found to be necessary for keeping HSCs in the bone marrow alive.

"We think that these mesenchymal stem cells are a very important component of the stem cell niche in the bone marrow," said Dr. Frenette. "These cells likely play important roles in stem cell maintenance, movement, and regeneration of the bone marrow. Further studies into their functions might allow us to maintain healthy stem cells and develop new methods to expand them for clinical use."

In addition to Dr. Frenette's former colleagues at Mt. Sinai, other scientists involved in the study are from Cold Spring Harbor Laboratory in Cold Spring, NY and Harvard Medical School in Boston, MA.


Story Source:

The above story is based on materials provided by Albert Einstein College of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Albert Einstein College of Medicine. "Two types of bone marrow stem cells could work together to advance regenerative medicine." ScienceDaily. ScienceDaily, 17 August 2010. <www.sciencedaily.com/releases/2010/08/100817090808.htm>.
Albert Einstein College of Medicine. (2010, August 17). Two types of bone marrow stem cells could work together to advance regenerative medicine. ScienceDaily. Retrieved October 26, 2014 from www.sciencedaily.com/releases/2010/08/100817090808.htm
Albert Einstein College of Medicine. "Two types of bone marrow stem cells could work together to advance regenerative medicine." ScienceDaily. www.sciencedaily.com/releases/2010/08/100817090808.htm (accessed October 26, 2014).

Share This



More Health & Medicine News

Sunday, October 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
Toxin-Packed Stem Cells Used To Kill Cancer

Toxin-Packed Stem Cells Used To Kill Cancer

Newsy (Oct. 25, 2014) — A Harvard University Research Team created genetically engineered stem cells that are able to kill cancer cells, while leaving other cells unharmed. Video provided by Newsy
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins