Featured Research

from universities, journals, and other organizations

Two types of bone marrow stem cells could work together to advance regenerative medicine

Date:
August 17, 2010
Source:
Albert Einstein College of Medicine
Summary:
A unique "partnership" between two types of bone marrow stem cells could lead to advances in regenerative medicine.

A study led by a researcher at Albert Einstein College of Medicine of Yeshiva University has revealed a unique "partnership" between two types of bone marrow stem cells, which could lead to advances in regenerative medicine. The aim of regenerative medicine is to enable the body to repair, replace, restore or regenerate damaged or diseased cells, tissues and organs.

Related Articles


The study was led by Paul Frenette, M.D., the new director of the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Einstein. Dr. Frenette conducted the research while at Mt. Sinai School of Medicine in New York City.

Hematopoietic stem cells (HSCs) in the bone marrow perform the vital task of producing all blood cells in the human body. Now, the new study, published in the August 12 issue of Nature, has revealed that HSCs pair up in the bone marrow with another type of stem cells, known as mesenchymal stem cells, which give rise to bone, cartilage, fat and other tissues. This pairing, the research shows, form a unique stem cell "partnership" that could lead to advances in regenerative medicine.

The identity of cells in close proximity to HSCs had been a matter of dispute. Dr. Frenette and his team not only found that HSCs and mesenchymal stem cells partner physically with each other, but they also showed that the two types of stem cells interact in crucially important ways. Mesenchymal cells, for example, were found to be necessary for keeping HSCs in the bone marrow alive.

"We think that these mesenchymal stem cells are a very important component of the stem cell niche in the bone marrow," said Dr. Frenette. "These cells likely play important roles in stem cell maintenance, movement, and regeneration of the bone marrow. Further studies into their functions might allow us to maintain healthy stem cells and develop new methods to expand them for clinical use."

In addition to Dr. Frenette's former colleagues at Mt. Sinai, other scientists involved in the study are from Cold Spring Harbor Laboratory in Cold Spring, NY and Harvard Medical School in Boston, MA.


Story Source:

The above story is based on materials provided by Albert Einstein College of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Albert Einstein College of Medicine. "Two types of bone marrow stem cells could work together to advance regenerative medicine." ScienceDaily. ScienceDaily, 17 August 2010. <www.sciencedaily.com/releases/2010/08/100817090808.htm>.
Albert Einstein College of Medicine. (2010, August 17). Two types of bone marrow stem cells could work together to advance regenerative medicine. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2010/08/100817090808.htm
Albert Einstein College of Medicine. "Two types of bone marrow stem cells could work together to advance regenerative medicine." ScienceDaily. www.sciencedaily.com/releases/2010/08/100817090808.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins