Featured Research

from universities, journals, and other organizations

Two types of bone marrow stem cells could work together to advance regenerative medicine

Date:
August 17, 2010
Source:
Albert Einstein College of Medicine
Summary:
A unique "partnership" between two types of bone marrow stem cells could lead to advances in regenerative medicine.

A study led by a researcher at Albert Einstein College of Medicine of Yeshiva University has revealed a unique "partnership" between two types of bone marrow stem cells, which could lead to advances in regenerative medicine. The aim of regenerative medicine is to enable the body to repair, replace, restore or regenerate damaged or diseased cells, tissues and organs.

Related Articles


The study was led by Paul Frenette, M.D., the new director of the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Einstein. Dr. Frenette conducted the research while at Mt. Sinai School of Medicine in New York City.

Hematopoietic stem cells (HSCs) in the bone marrow perform the vital task of producing all blood cells in the human body. Now, the new study, published in the August 12 issue of Nature, has revealed that HSCs pair up in the bone marrow with another type of stem cells, known as mesenchymal stem cells, which give rise to bone, cartilage, fat and other tissues. This pairing, the research shows, form a unique stem cell "partnership" that could lead to advances in regenerative medicine.

The identity of cells in close proximity to HSCs had been a matter of dispute. Dr. Frenette and his team not only found that HSCs and mesenchymal stem cells partner physically with each other, but they also showed that the two types of stem cells interact in crucially important ways. Mesenchymal cells, for example, were found to be necessary for keeping HSCs in the bone marrow alive.

"We think that these mesenchymal stem cells are a very important component of the stem cell niche in the bone marrow," said Dr. Frenette. "These cells likely play important roles in stem cell maintenance, movement, and regeneration of the bone marrow. Further studies into their functions might allow us to maintain healthy stem cells and develop new methods to expand them for clinical use."

In addition to Dr. Frenette's former colleagues at Mt. Sinai, other scientists involved in the study are from Cold Spring Harbor Laboratory in Cold Spring, NY and Harvard Medical School in Boston, MA.


Story Source:

The above story is based on materials provided by Albert Einstein College of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Albert Einstein College of Medicine. "Two types of bone marrow stem cells could work together to advance regenerative medicine." ScienceDaily. ScienceDaily, 17 August 2010. <www.sciencedaily.com/releases/2010/08/100817090808.htm>.
Albert Einstein College of Medicine. (2010, August 17). Two types of bone marrow stem cells could work together to advance regenerative medicine. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2010/08/100817090808.htm
Albert Einstein College of Medicine. "Two types of bone marrow stem cells could work together to advance regenerative medicine." ScienceDaily. www.sciencedaily.com/releases/2010/08/100817090808.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins