Featured Research

from universities, journals, and other organizations

Using PEAT to capture, share and analyze protein experimental data

Date:
October 22, 2010
Source:
UCD Conway Institute of Biomolecular & Biomedical Research
Summary:
Researchers in Ireland have created a novel application that not only facilitates the analysis of experimental data generated in the course of a research project but also ensures that this valuable data is available for future use.

Researchers in Ireland's UCD Conway Institute led by Conway Fellow, Dr Jens Erik Nielsen have created a novel application that not only facilitates the analysis of experimental data generated in the course of a research project but also ensures that this valuable data is available for future use. The team described the application in an article published recently in the journal, Nucleic Acids Research.

Related Articles


PEAT (Protein Engineering Analysis Tool) is not simply another laboratory information management system, but has been designed to address specific tasks encountered in a typical protein engineering project while integrating data deposition in the process.

Proteins are often described as the building blocks within organisms given their central role in critical cell functions. When changes occur in the structure or function of proteins, diseases such as Alzheimer's or cancer can result. Consequently, a significant proportion of research efforts concentrate on dissecting, optimising or changing proteins in an effort to find new treatments for such diseases.

Vast amounts of data are generated annually through the protein engineering techniques used in the process of studying proteins. Although this valuable experimental data could be used in other research projects, there is no requirement to deposit it in a database before publishing and so it is unavailable for re-analysis or essentially 'lost' within the pages of a thesis or journal article.

Commenting on the benefits of PEAT, Dr Nielsen said, "The task of data capture and database deposition is often seen as a tedious and unrewarding process. PEAT incentivises data storage by integrating the process with the analysis tools in a single application. I hope that researchers will see the benefits of using PEAT so that we can create and share high quality datasets on the connections between protein sequence, structure and function."

PEAT is written in the python programming language and, although still under active development, has been road tested on several projects within Nielsen's laboratory, and has been used to establish several online databases. Additional functionality specific to particular research projects can be implemented with specifically written plug-ins that allow users to tailor the functionality of PEAT to specific experiments, proteins or scientific questions.


Story Source:

The above story is based on materials provided by UCD Conway Institute of Biomolecular & Biomedical Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. Damien Farrell, Fergal O’Meara, Michael Johnston, John Bradley, Chresten R. Søndergaard, Nikolaj Georgi, Helen Webb, Barbara Mary Tynan-Connolly, Una Bjarnadottir, Tommy Carstensen, Jens Erik Nielsen. Capturing, sharing and analysing biophysical data from protein engineering and protein characterization studies. Nucleic Acids Research, 2010; DOI: 10.1093/nar/gkq726

Cite This Page:

UCD Conway Institute of Biomolecular & Biomedical Research. "Using PEAT to capture, share and analyze protein experimental data." ScienceDaily. ScienceDaily, 22 October 2010. <www.sciencedaily.com/releases/2010/10/101020084231.htm>.
UCD Conway Institute of Biomolecular & Biomedical Research. (2010, October 22). Using PEAT to capture, share and analyze protein experimental data. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2010/10/101020084231.htm
UCD Conway Institute of Biomolecular & Biomedical Research. "Using PEAT to capture, share and analyze protein experimental data." ScienceDaily. www.sciencedaily.com/releases/2010/10/101020084231.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Computers & Math News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Recharge Your Phone in 30 Seconds? Israeli Firm Says It Can

Recharge Your Phone in 30 Seconds? Israeli Firm Says It Can

Reuters - Innovations Video Online (Nov. 28, 2014) — With consumers demanding more and more from their mobile devices, scientists in Israel and Singapore are developing super fast-charging batteries to power them. Amy Pollock has more. Video provided by Reuters
Powered by NewsLook.com
EU Pushes Google For Worldwide Right To Be Forgotten

EU Pushes Google For Worldwide Right To Be Forgotten

Newsy (Nov. 27, 2014) — Privacy regulators recommend Google expand its requested removals to apply to all its web domains. Video provided by Newsy
Powered by NewsLook.com
Predictions Of Tablets' Demise Sound Familiar

Predictions Of Tablets' Demise Sound Familiar

Newsy (Nov. 26, 2014) — The tablet's days are numbered, at least according to a recent IDC report. The market-research firm paints a grim outlook for tablets. Video provided by Newsy
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins