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E. coli infection linked to long-term health problems

Date:
November 19, 2010
Source:
BMJ-British Medical Journal
Summary:
People who contract gastroenteritis from drinking water contaminated with E coli are at an increased risk of developing high blood pressure, kidney problems and heart disease in later life, finds a new study.
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Under a magnification of 6836x, this colorized scanning electron micrograph (SEM) depicted a number of Gram-negative Escherichia coli bacteria of the strain O157:H7, which is one of hundreds of strains of this bacterium. Although most strains are harmless, and live in the intestines of healthy humans and animals, this strain produces a powerful toxin, which can cause severe illness.
Credit: Janice Haney Carr

People who contract gastroenteritis from drinking water contaminated with E. coli are at an increased risk of developing high blood pressure, kidney problems and heart disease in later life, finds a study published on the British Medical Journal website.

The findings underline the importance of ensuring a safe food and water supply and the need for regular monitoring for those affected.

It is estimated that E. coli O157:H7 infections cause up to 120,000 gastro-enteric illnesses annually in the US alone, resulting in over 2,000 hospitalisations and 60 deaths. However, the long term health effects of E. coli infection in adults are largely unknown.

So a team of researchers in Canada assessed the risk for hypertension, renal impairment and cardiovascular disease within eight years of gastroenteritis from drinking contaminated water.

They used data from the Walkerton Health Study -- the first study to evaluate long term health after an outbreak of gastroenteritis in May 2000 when a municipal water system became contaminated with E. coli O157:H7 and Campylobacter bacteria.

Study participants were surveyed annually and underwent a physical examination and laboratory assessment to track their long term health.

Of 1,977 adult participants, 1,067 (54%) experienced acute gastroenteritis of whom 378 sought medical attention.

Compared with participants who were not ill or only mildly ill during the outbreak, participants who experienced acute gastroenteritis were 1.3 times more likely to develop hypertension, 3.4 times more likely to develop renal impairment, and 2.1 times more likely to have a cardiovascular event, such as a heart attack or stroke.

The authors conclude: "Our findings underline the need for following up individual cases of food or water poisoning by E. coli O157:H7 to prevent or reduce silent progressive vascular injury."

They add: "These long term consequences emphasise the importance of ensuring safe food and water supply as a cornerstone of public health."


Story Source:

The above post is reprinted from materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. W. F. Clark, J. M. Sontrop, J. J. Macnab, M. Salvadori, L. Moist, R. Suri, A. X. Garg. Long term risk for hypertension, renal impairment, and cardiovascular disease after gastroenteritis from drinking water contaminated with Escherichia coli O157:H7: a prospective cohort study. BMJ, 2010; 341 (nov17 2): c6020 DOI: 10.1136/bmj.c6020

Cite This Page:

BMJ-British Medical Journal. "E. coli infection linked to long-term health problems." ScienceDaily. ScienceDaily, 19 November 2010. <www.sciencedaily.com/releases/2010/11/101118194607.htm>.
BMJ-British Medical Journal. (2010, November 19). E. coli infection linked to long-term health problems. ScienceDaily. Retrieved August 1, 2015 from www.sciencedaily.com/releases/2010/11/101118194607.htm
BMJ-British Medical Journal. "E. coli infection linked to long-term health problems." ScienceDaily. www.sciencedaily.com/releases/2010/11/101118194607.htm (accessed August 1, 2015).

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