Featured Research

from universities, journals, and other organizations

Safer and more effective diabetes control with basal insulin analogs

Date:
June 24, 2011
Source:
Mary Ann Liebert, Inc.
Summary:
Basal insulin analogs have revolutionized diabetes care, and especially the treatment of Type 2 diabetes, enabling patients to achieve better control of blood glucose levels while reducing hypoglycemic episodes. These revolutionary, long-acting basal insulin analogs are intended to replace the natural insulin missing in diabetes. They are infusion pumps that provide subcutaneous, continuous delivery of insulin to mimic the function of a normal pancreas.

Basal insulin analogs have revolutionized diabetes care, and especially the treatment of type 2 diabetes, enabling patients to achieve better control of blood glucose levels while reducing hypoglycemic episodes. These revolutionary, long-acting basal insulin analogs, intended to replace the natural insulin missing in diabetes, and infusion pumps that provide subcutaneous, continuous delivery of insulin to mimic the function of a normal pancreas, are described in a special supplement to Diabetes Technology & Therapeutics, a peer-reviewed journal published by Mary Ann Liebert, Inc.

Related Articles


More than 25 million people in the U.S. have diabetes, and the global diabetes epidemic is estimated to affect nearly 440 million people by 2030. "The development of basal insulin analogs has greatly impacted the management of diabetes," writes Satish Garg, MD, Editor-in-Chief of Diabetes Technology & Therapeutics and Professor of Medicine and Pediatrics at the University of Colorado Denver, and Emily Moser, University of Colorado Denver School of Medicine, in their Editorial introducing the broad scope of articles in this issue that detail the history, current status, and clinic promise of ongoing advances in basal insulin analogs and insulin delivery devices.

The controversial role postprandial glucose (PPG) -- spikes in blood sugar levels after eating -- plays in overall hyperglycemia and in the development of diabetes complications in patients with type 2 diabetes is the focus of an article by Louis Monnier, MD, Claude Colette, PhD, and David Owens, MD, University of Montpellier (France) and University Hospital Llandough (Cardiff, United Kingdom), entitled "Postprandial and Basal Glucose in Type 2 Diabetes: Assessment and Respective Impacts."

Geremia Bolli, MD, Anna Marinelli Andreoli, MD, and Paola Lucidi, MD, PhD, University of Perugia (Italy), review the critical role of basal insulin in maintaining normal blood glucose levels and explain the importance of optimizing basal insulin substitution in individuals with type 1 diabetes. The authors explore the advantages and limitations of the most recent options for basal insulin substitution, including long-acting insulin analogs and continuous subcutaneous insulin infusion. In the article "Optimizing the Replacement of Basal Insulin in Type 1 Diabetes Mellitus: No Longer an Elusive Goal in the Post-NPH Era," the authors conclude that modern physiological basal insulin replacement, combined with other standards of care and patient and physician education, make optimal blood sugar and HbA1c control a realistic target of diabetes management.

In their Concluding Remarks on "The Future of Basal Insulin Supplementation," Airin Simon, MD and J. Hans DeVries, MD, PhD, Academic Medical Centre (Amsterdam, The Netherlands), preview and compare the basal insulin analogs and patch pumps for subcutaneous insulin delivery that are now in development. The results of ongoing clinical studies are promising, but final trial results (being presented at the American Diabetes Association's annual meeting this week in San Diego) are needed to confirm their safety, efficacy, and cost effectiveness.


Story Source:

The above story is based on materials provided by Mary Ann Liebert, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

Mary Ann Liebert, Inc.. "Safer and more effective diabetes control with basal insulin analogs." ScienceDaily. ScienceDaily, 24 June 2011. <www.sciencedaily.com/releases/2011/06/110624162253.htm>.
Mary Ann Liebert, Inc.. (2011, June 24). Safer and more effective diabetes control with basal insulin analogs. ScienceDaily. Retrieved March 1, 2015 from www.sciencedaily.com/releases/2011/06/110624162253.htm
Mary Ann Liebert, Inc.. "Safer and more effective diabetes control with basal insulin analogs." ScienceDaily. www.sciencedaily.com/releases/2011/06/110624162253.htm (accessed March 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com
The Best Tips to Makeover Your Health

The Best Tips to Makeover Your Health

Buzz60 (Feb. 27, 2015) If you&apos;re looking to boost your health this season, there are a few quick and easy steps to prompt you for success. Krystin Goodwin (@Krystingoodwin) has the best tips to give your health a makeover this spring! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins