Featured Research

from universities, journals, and other organizations

Safer and more effective diabetes control with basal insulin analogs

Date:
June 24, 2011
Source:
Mary Ann Liebert, Inc.
Summary:
Basal insulin analogs have revolutionized diabetes care, and especially the treatment of Type 2 diabetes, enabling patients to achieve better control of blood glucose levels while reducing hypoglycemic episodes. These revolutionary, long-acting basal insulin analogs are intended to replace the natural insulin missing in diabetes. They are infusion pumps that provide subcutaneous, continuous delivery of insulin to mimic the function of a normal pancreas.

Basal insulin analogs have revolutionized diabetes care, and especially the treatment of type 2 diabetes, enabling patients to achieve better control of blood glucose levels while reducing hypoglycemic episodes. These revolutionary, long-acting basal insulin analogs, intended to replace the natural insulin missing in diabetes, and infusion pumps that provide subcutaneous, continuous delivery of insulin to mimic the function of a normal pancreas, are described in a special supplement to Diabetes Technology & Therapeutics, a peer-reviewed journal published by Mary Ann Liebert, Inc.

Related Articles


More than 25 million people in the U.S. have diabetes, and the global diabetes epidemic is estimated to affect nearly 440 million people by 2030. "The development of basal insulin analogs has greatly impacted the management of diabetes," writes Satish Garg, MD, Editor-in-Chief of Diabetes Technology & Therapeutics and Professor of Medicine and Pediatrics at the University of Colorado Denver, and Emily Moser, University of Colorado Denver School of Medicine, in their Editorial introducing the broad scope of articles in this issue that detail the history, current status, and clinic promise of ongoing advances in basal insulin analogs and insulin delivery devices.

The controversial role postprandial glucose (PPG) -- spikes in blood sugar levels after eating -- plays in overall hyperglycemia and in the development of diabetes complications in patients with type 2 diabetes is the focus of an article by Louis Monnier, MD, Claude Colette, PhD, and David Owens, MD, University of Montpellier (France) and University Hospital Llandough (Cardiff, United Kingdom), entitled "Postprandial and Basal Glucose in Type 2 Diabetes: Assessment and Respective Impacts."

Geremia Bolli, MD, Anna Marinelli Andreoli, MD, and Paola Lucidi, MD, PhD, University of Perugia (Italy), review the critical role of basal insulin in maintaining normal blood glucose levels and explain the importance of optimizing basal insulin substitution in individuals with type 1 diabetes. The authors explore the advantages and limitations of the most recent options for basal insulin substitution, including long-acting insulin analogs and continuous subcutaneous insulin infusion. In the article "Optimizing the Replacement of Basal Insulin in Type 1 Diabetes Mellitus: No Longer an Elusive Goal in the Post-NPH Era," the authors conclude that modern physiological basal insulin replacement, combined with other standards of care and patient and physician education, make optimal blood sugar and HbA1c control a realistic target of diabetes management.

In their Concluding Remarks on "The Future of Basal Insulin Supplementation," Airin Simon, MD and J. Hans DeVries, MD, PhD, Academic Medical Centre (Amsterdam, The Netherlands), preview and compare the basal insulin analogs and patch pumps for subcutaneous insulin delivery that are now in development. The results of ongoing clinical studies are promising, but final trial results (being presented at the American Diabetes Association's annual meeting this week in San Diego) are needed to confirm their safety, efficacy, and cost effectiveness.


Story Source:

The above story is based on materials provided by Mary Ann Liebert, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

Mary Ann Liebert, Inc.. "Safer and more effective diabetes control with basal insulin analogs." ScienceDaily. ScienceDaily, 24 June 2011. <www.sciencedaily.com/releases/2011/06/110624162253.htm>.
Mary Ann Liebert, Inc.. (2011, June 24). Safer and more effective diabetes control with basal insulin analogs. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2011/06/110624162253.htm
Mary Ann Liebert, Inc.. "Safer and more effective diabetes control with basal insulin analogs." ScienceDaily. www.sciencedaily.com/releases/2011/06/110624162253.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins