Featured Research

from universities, journals, and other organizations

Systematic osteoporosis management urged after vertebral fracture augmentation

Date:
August 1, 2011
Source:
International Osteoporosis Foundation
Summary:
Scientists have issued a literature review of prospective controlled studies comparing the efficacy and safety of two minimally invasive techniques for vertebral augmentation after spine fracture: vertebroplasty and balloon kyphoplasty. The review also lists important recommendations to facilitate the comparison of future studies and highlights research questions still unresolved.

A working group of the International Osteoporosis Foundation (IOF) has issued a literature review of prospective controlled studies comparing the efficacy and safety of two minimally invasive techniques for vertebral augmentation after spine fracture: vertebroplasty (VP) and balloon kyphoplasty (BKP). The review also lists important recommendations to facilitate the comparison of future studies and highlights research questions still unresolved.

Vertebral fractures, most often due to osteoporosis, are associated with acute or chronic back pain, disability and kyphosis (stooped back). One in five women with a vertebral fracture will sustain another within a year, which may lead to a 'cascade' of fractures. Vertebral fractures impact severely on quality of life and may have serious health consequences such as spinal deformity, immobility, decreased pulmonary function, early satiety and impaired gait. Clinical vertebral fractures are also associated with an 8-fold increase in mortality.

Conservative treatment of vertebral fractures is typically through rest, pain medication, bracing and muscle relaxants. VP and BKP are two minimally invasive techniques that consist of inserting a bone cement into the compressed vertebra and stabilising the fracture.

In the studies observed, the review found that:

  • Overall, VP and BKP are relatively safe procedures and serious complications are rare.
  • In the short term, VP and BKP provide quicker pain relief and mobility recovery than does conservative treatment alone.
  • VP and BKP are able to stabilise the fracture and in some cases restore lost vertebral body height.
  • The added benefit of injecting cement over a sham-controlled surgery is still contentious.
  • The clinical outcome after VP and BKP appears to be dependent on the time elapsed between the fracture and the intervention.
  • The incidence of new (including adjacent) vertebral fractures are similar after VP or BKP, but longer term data are required.
  • Further studies are needed with standardised and systematic reporting of health outcomes and complications.

Kristina Åkesson, chair of the IOF Fracture Working Group and Professor at the Department of Orthopedics, Skåne University Hospital Malmö in Sweden, stated, "Referring physicians should be aware that VP and BKP are available options for the management of vertebral compression fractures, with possible clinical benefits to their patients in terms of acute pain relief and improved quality of life. However, longer follow-up of patients are needed to ensure the efficacy and safety of these techniques, which should not be considered as a substitute for the medical management of osteoporosis, vitally needed in these patients at high risk of other fractures."


Story Source:

The above story is based on materials provided by International Osteoporosis Foundation. Note: Materials may be edited for content and length.


Journal Reference:

  1. S. Boonen, D. A. Wahl, L. Nauroy, M. L. Brandi, M. L. Bouxsein, J. Goldhahn, E. M. Lewiecki, G. P. Lyritis, D. Marsh, K. Obrant, S. Silverman, E. Siris, K. Åkesson. Balloon kyphoplasty and vertebroplasty in the management of vertebral compression fractures. Osteoporosis International, 2011; DOI: 10.1007/s00198-011-1639-5

Cite This Page:

International Osteoporosis Foundation. "Systematic osteoporosis management urged after vertebral fracture augmentation." ScienceDaily. ScienceDaily, 1 August 2011. <www.sciencedaily.com/releases/2011/08/110801111748.htm>.
International Osteoporosis Foundation. (2011, August 1). Systematic osteoporosis management urged after vertebral fracture augmentation. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2011/08/110801111748.htm
International Osteoporosis Foundation. "Systematic osteoporosis management urged after vertebral fracture augmentation." ScienceDaily. www.sciencedaily.com/releases/2011/08/110801111748.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) — Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) — In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) — A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) — The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins