Featured Research

from universities, journals, and other organizations

New discovery in battle against infections

Date:
August 10, 2011
Source:
Trudeau Institute
Summary:
Researchers have now identified a previously unknown link between the migration of white blood cells to infected tissues and the ability of these cells to survive and become long-lived memory cells after the infection has been cleared.

Researchers from Dr. Woodland's lab at the Trudeau Institute have now identified a previously unknown link between the migration of white blood cells to infected tissues and the ability of these cells to survive and become long-lived memory cells after the infection has been cleared. The new data is featured on the cover of this month's The Journal of Experimental Medicine.

"Defining the factors that regulate the generation of these long-lived memory cells is crucial, as these are the cells that provide protection from re-infection," said Dr. David Woodland. "Our study focuses on influenza and tuberculosis infections, but a similar study from our colleagues in Japan that was published simultaneously in The Journal of Experimental Medicine shows this observation is relevant to other pathogens, suggesting these findings may be applicable to many infectious diseases. Hopefully, we can use this information to design vaccines that generate larger numbers of memory cells and can therefore provide better protective immunity."

The lab envisions the findings will lead to the development of additives that act to boost vaccine efficacy. This would be especially important for the elderly population that tends to be difficult to effectively vaccinate.

Dr. Woodland's studies are funded by the Trudeau Institute and grants from the National Institutes of Health.


Story Source:

The above story is based on materials provided by Trudeau Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. E. Kohlmeier, W. W. Reiley, G. Perona-Wright, M. L. Freeman, E. J. Yager, L. M. Connor, E. L. Brincks, T. Cookenham, A. D. Roberts, C. E. Burkum, S. Sell, G. M. Winslow, M. A. Blackman, M. Mohrs, D. L. Woodland. Inflammatory chemokine receptors regulate CD8 T cell contraction and memory generation following infection. Journal of Experimental Medicine, 2011; 208 (8): 1621 DOI: 10.1084/jem.20102110

Cite This Page:

Trudeau Institute. "New discovery in battle against infections." ScienceDaily. ScienceDaily, 10 August 2011. <www.sciencedaily.com/releases/2011/08/110810101557.htm>.
Trudeau Institute. (2011, August 10). New discovery in battle against infections. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2011/08/110810101557.htm
Trudeau Institute. "New discovery in battle against infections." ScienceDaily. www.sciencedaily.com/releases/2011/08/110810101557.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins