Featured Research

from universities, journals, and other organizations

New discovery in battle against infections

Date:
August 10, 2011
Source:
Trudeau Institute
Summary:
Researchers have now identified a previously unknown link between the migration of white blood cells to infected tissues and the ability of these cells to survive and become long-lived memory cells after the infection has been cleared.

Researchers from Dr. Woodland's lab at the Trudeau Institute have now identified a previously unknown link between the migration of white blood cells to infected tissues and the ability of these cells to survive and become long-lived memory cells after the infection has been cleared. The new data is featured on the cover of this month's The Journal of Experimental Medicine.

Related Articles


"Defining the factors that regulate the generation of these long-lived memory cells is crucial, as these are the cells that provide protection from re-infection," said Dr. David Woodland. "Our study focuses on influenza and tuberculosis infections, but a similar study from our colleagues in Japan that was published simultaneously in The Journal of Experimental Medicine shows this observation is relevant to other pathogens, suggesting these findings may be applicable to many infectious diseases. Hopefully, we can use this information to design vaccines that generate larger numbers of memory cells and can therefore provide better protective immunity."

The lab envisions the findings will lead to the development of additives that act to boost vaccine efficacy. This would be especially important for the elderly population that tends to be difficult to effectively vaccinate.

Dr. Woodland's studies are funded by the Trudeau Institute and grants from the National Institutes of Health.


Story Source:

The above story is based on materials provided by Trudeau Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. E. Kohlmeier, W. W. Reiley, G. Perona-Wright, M. L. Freeman, E. J. Yager, L. M. Connor, E. L. Brincks, T. Cookenham, A. D. Roberts, C. E. Burkum, S. Sell, G. M. Winslow, M. A. Blackman, M. Mohrs, D. L. Woodland. Inflammatory chemokine receptors regulate CD8 T cell contraction and memory generation following infection. Journal of Experimental Medicine, 2011; 208 (8): 1621 DOI: 10.1084/jem.20102110

Cite This Page:

Trudeau Institute. "New discovery in battle against infections." ScienceDaily. ScienceDaily, 10 August 2011. <www.sciencedaily.com/releases/2011/08/110810101557.htm>.
Trudeau Institute. (2011, August 10). New discovery in battle against infections. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2011/08/110810101557.htm
Trudeau Institute. "New discovery in battle against infections." ScienceDaily. www.sciencedaily.com/releases/2011/08/110810101557.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins