Featured Research

from universities, journals, and other organizations

Uterine rupture is rare in the UK but increases with the number of previous cesarean deliveries

Date:
March 13, 2012
Source:
Public Library of Science
Summary:
An analysis of the UK Obstetric Surveillance System shows that uterine rupture -- a serious complication of pregnancy in which the wall of the uterus tears during pregnancy or early labor -- is rare but for women who have previously had a cesarean section, the risk of rupture increases with the number of previous cesarean deliveries, a short interval since the last cesarean section, and with induced labor.

An analysis of the UK Obstetric Surveillance System published in PLoS Medicine shows that uterine rupture -- a serious complication of pregnancy in which the wall of the uterus (womb) tears during pregnancy or early labour -- is rare but for women who have previously had a caesarean section, the risk of rupture increases with the number of previous caesarean deliveries, a short interval since the last caesarean section, and with induced labour.

Kathryn Fitzpatrick and colleagues from the National Perinatal Epidemiology Unit based at the University of Oxford in the UK found that from April 2009 to April 2010, 159 women experienced uterine rupture in the UK, of whom 139 had previously delivered by a caesarean section.

The researchers found that overall, the incidence of uterine rupture was 0.2 per 1000 pregnancies but in women with a previous caesarean section, 0.21% of pregnancies resulted in uterine rupture in women planning vaginal delivery and 0.03% in those experiencing a repeat caesarean delivery.

Furthermore, the risk of uterine rupture was greatest among those who had had two or more previous caesarean deliveries or a caesarean delivery less than 12 months previously, or whose labor was induced.

In their detailed analysis, the researchers found that two women died following uterine rupture (giving a case fatality rate of 1.3%) and 18 babies died around the time of birth (giving a perinatal mortality rate of 124 per 1000 live births -- the overall UK perinatal mortality rate is 7.5 per 1000 live births).

The authors say: "Although uterine rupture is associated with significant maternal and perinatal mortality and morbidity, even amongst women with a previous caesarean section planning a vaginal delivery in their current pregnancy, it is rare, occurring in only one of every 500 women."

The authors conclude: "For women with a previous caesarean section, the risk of uterine rupture increases not only with trial of labour but also with the number of previous caesarean deliveries, a short interval since the last caesarean section, and labour induction and/or augmentation. These factors should be considered when counselling and managing the labour of women with a previous caesarean section."

In an accompanying Perspective, Catherine Spong from the National Institute of Child Health and Human Development in the USA (uninvolved in the research study) says:

"Given the major complications associated with multiple cesareans, to both mother and baby, women should carefully evaluate the immediate risks in the current pregnancy with the longer-term risks of multiple cesareans."


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal References:

  1. Kathryn E. Fitzpatrick, Jennifer J. Kurinczuk, Zarko Alfirevic, Patsy Spark, Peter Brocklehurst, Marian Knight. Uterine Rupture by Intended Mode of Delivery in the UK: A National Case-Control Study. PLoS Medicine, 2012; 9 (3): e1001184 DOI: 10.1371/journal.pmed.1001184
  2. Catherine Y. Spong. To VBAC or Not to VBAC. PLoS Medicine, 2012; 9 (3): e1001191 DOI: 10.1371/journal.pmed.1001191

Cite This Page:

Public Library of Science. "Uterine rupture is rare in the UK but increases with the number of previous cesarean deliveries." ScienceDaily. ScienceDaily, 13 March 2012. <www.sciencedaily.com/releases/2012/03/120313185848.htm>.
Public Library of Science. (2012, March 13). Uterine rupture is rare in the UK but increases with the number of previous cesarean deliveries. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2012/03/120313185848.htm
Public Library of Science. "Uterine rupture is rare in the UK but increases with the number of previous cesarean deliveries." ScienceDaily. www.sciencedaily.com/releases/2012/03/120313185848.htm (accessed April 16, 2014).

Share This



More Health & Medicine News

Wednesday, April 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com
Cognitive Function: Is It All Downhill From Age 24?

Cognitive Function: Is It All Downhill From Age 24?

Newsy (Apr. 15, 2014) A new study out of Canada says cognitive motor performance begins deteriorating around age 24. Video provided by Newsy
Powered by NewsLook.com
How Mt. Everest Helped Scientists Research Diabetes

How Mt. Everest Helped Scientists Research Diabetes

Newsy (Apr. 15, 2014) British researchers were able to use Mount Everest's low altitudes to study insulin resistance. They hope to find ways to treat diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins