Featured Research

from universities, journals, and other organizations

Uterine rupture is rare in the UK but increases with the number of previous cesarean deliveries

Date:
March 13, 2012
Source:
Public Library of Science
Summary:
An analysis of the UK Obstetric Surveillance System shows that uterine rupture -- a serious complication of pregnancy in which the wall of the uterus tears during pregnancy or early labor -- is rare but for women who have previously had a cesarean section, the risk of rupture increases with the number of previous cesarean deliveries, a short interval since the last cesarean section, and with induced labor.

An analysis of the UK Obstetric Surveillance System published in PLoS Medicine shows that uterine rupture -- a serious complication of pregnancy in which the wall of the uterus (womb) tears during pregnancy or early labour -- is rare but for women who have previously had a caesarean section, the risk of rupture increases with the number of previous caesarean deliveries, a short interval since the last caesarean section, and with induced labour.

Kathryn Fitzpatrick and colleagues from the National Perinatal Epidemiology Unit based at the University of Oxford in the UK found that from April 2009 to April 2010, 159 women experienced uterine rupture in the UK, of whom 139 had previously delivered by a caesarean section.

The researchers found that overall, the incidence of uterine rupture was 0.2 per 1000 pregnancies but in women with a previous caesarean section, 0.21% of pregnancies resulted in uterine rupture in women planning vaginal delivery and 0.03% in those experiencing a repeat caesarean delivery.

Furthermore, the risk of uterine rupture was greatest among those who had had two or more previous caesarean deliveries or a caesarean delivery less than 12 months previously, or whose labor was induced.

In their detailed analysis, the researchers found that two women died following uterine rupture (giving a case fatality rate of 1.3%) and 18 babies died around the time of birth (giving a perinatal mortality rate of 124 per 1000 live births -- the overall UK perinatal mortality rate is 7.5 per 1000 live births).

The authors say: "Although uterine rupture is associated with significant maternal and perinatal mortality and morbidity, even amongst women with a previous caesarean section planning a vaginal delivery in their current pregnancy, it is rare, occurring in only one of every 500 women."

The authors conclude: "For women with a previous caesarean section, the risk of uterine rupture increases not only with trial of labour but also with the number of previous caesarean deliveries, a short interval since the last caesarean section, and labour induction and/or augmentation. These factors should be considered when counselling and managing the labour of women with a previous caesarean section."

In an accompanying Perspective, Catherine Spong from the National Institute of Child Health and Human Development in the USA (uninvolved in the research study) says:

"Given the major complications associated with multiple cesareans, to both mother and baby, women should carefully evaluate the immediate risks in the current pregnancy with the longer-term risks of multiple cesareans."


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal References:

  1. Kathryn E. Fitzpatrick, Jennifer J. Kurinczuk, Zarko Alfirevic, Patsy Spark, Peter Brocklehurst, Marian Knight. Uterine Rupture by Intended Mode of Delivery in the UK: A National Case-Control Study. PLoS Medicine, 2012; 9 (3): e1001184 DOI: 10.1371/journal.pmed.1001184
  2. Catherine Y. Spong. To VBAC or Not to VBAC. PLoS Medicine, 2012; 9 (3): e1001191 DOI: 10.1371/journal.pmed.1001191

Cite This Page:

Public Library of Science. "Uterine rupture is rare in the UK but increases with the number of previous cesarean deliveries." ScienceDaily. ScienceDaily, 13 March 2012. <www.sciencedaily.com/releases/2012/03/120313185848.htm>.
Public Library of Science. (2012, March 13). Uterine rupture is rare in the UK but increases with the number of previous cesarean deliveries. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2012/03/120313185848.htm
Public Library of Science. "Uterine rupture is rare in the UK but increases with the number of previous cesarean deliveries." ScienceDaily. www.sciencedaily.com/releases/2012/03/120313185848.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Study Links Male-Pattern Baldness To Prostate Cancer

Study Links Male-Pattern Baldness To Prostate Cancer

Newsy (Sep. 16, 2014) New findings suggest men with a certain type of baldness at age 45 are 39 percent more likely to develop aggressive prostate cancer. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins