Featured Research

from universities, journals, and other organizations

Synthetic stool a prospective treatment for C. difficile

Date:
April 30, 2012
Source:
Queen's University
Summary:
A synthetic mixture of intestinal bacteria could one day replace stool transplants as a treatment for Clostridium difficile (C. difficile). C . difficile is a toxin-producing bacteria that can overpopulate the colon when antibiotics eradicate other, naturally protective bacteria living there.

A synthetic mixture of intestinal bacteria could one day replace stool transplants as a treatment for Clostridium difficile (C. difficile). C . difficile is a toxin-producing bacteria that can overpopulate the colon when antibiotics eradicate other, naturally protective bacteria living there.

"A synthetic stool transplant has a lot of potential because we can control what goes in and we can alter, change, or modify it as necessary," says Elaine Petrof, an assistant professor in the Department of Medicine at Queen's University and in the Gastrointestinal Disease Research Unit (GIDRU) at Kingston General Hospital.

Dr. Petrof and her collaborator at the University of Guelph, Emma Allen-Vercoe, believe that a stool compound made from synthetic or "purified" bacteria could significantly improve on regular stool transplants. It could eliminate the chance of transmitting an infectious disease through fecal bacteria; physicians could tailor the mixture so as to increase patient acceptance; it would be easily reproducible; and, it may appeal to both doctors and patients as a 'cleaner' therapy.

Dr. Petrof and Dr. Allen Vercoe, an anaerobic microbiologist specializing in intestinal bacteria, are working closely to develop such a therapy. The goal behind their synthetic stool project is to offer a single-dose remedy, putting an end to revolving-door hospital visits for patients with recurring symptoms. Currently, they are continuing their research before using it as a new therapy.

Dr. Petrof recently presented the project's preliminary findings at the Beneficial Microbes Conference in Noordwijkerhout, the Netherlands.


Story Source:

The above story is based on materials provided by Queen's University. Note: Materials may be edited for content and length.


Cite This Page:

Queen's University. "Synthetic stool a prospective treatment for C. difficile." ScienceDaily. ScienceDaily, 30 April 2012. <www.sciencedaily.com/releases/2012/04/120430152132.htm>.
Queen's University. (2012, April 30). Synthetic stool a prospective treatment for C. difficile. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/2012/04/120430152132.htm
Queen's University. "Synthetic stool a prospective treatment for C. difficile." ScienceDaily. www.sciencedaily.com/releases/2012/04/120430152132.htm (accessed April 21, 2014).

Share This



More Health & Medicine News

Monday, April 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Breakfast Foods Are Getting Pricier

Breakfast Foods Are Getting Pricier

AP (Apr. 21, 2014) Breakfast is now being served with a side of sticker shock. The cost of morning staples like bacon, coffee and orange juice is on the rise because of global supply problems. (April 21) Video provided by AP
Powered by NewsLook.com
Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins