Featured Research

from universities, journals, and other organizations

Study sheds light on lung cancers that are undetected by radiograph

Date:
September 2, 2012
Source:
European Lung Foundation
Summary:
New research has revealed why some lung cancers are undetected by radiograph and helped to identify the type of people who may be at risk of this form of the disease.

New research has revealed why some lung cancers are undetected by radiograph and helped to identify the type of people who may be at risk of this form of the disease.

The findings will be presented Monday (Sept. 3, 2012) at the European Respiratory Society's Annual Congress in Vienna.

There has been no significant reduction in lung cancer mortality rates in recent years. Chest radiographs can be used to screen for lung cancer. However, these aren't always effective and it appears that some cancers are later diagnosed even though individuals have received a negative chest radiograph within the previous 12 months.

The reason for this could be due to human error with the cancer being missed on the review of the radiograph, due to the cancer being undetectable by this form of screening technique, or because the cancer developed so rapidly that it both initiates and becomes evident in the time interval between screening tests.

Little is known about this form of lung cancer that is not detected by screening chest radiograph, which is referred to as an interval cancer. To improve the understanding of this type of the disease, researchers aimed to analyse the type of people who developed this cancer and the characteristics of the disease.

The research used data from a national screening trial in the USA. It followed 77,445 participants who were screened at the start of the study and then annually for either 2 or 3 years depending on their smoking status.

A total of 450 people were diagnosed with lung cancer during the years of chest radiograph screening, of which 152 were initially not spotted by the radiograph. Out of this group, 35% of lung cancers not initially identified on the radiograph were spotted when it was re-reviewed. The remaining 65% of this group therefore had 'true interval cancer' which was not detected on the initial screening, or the second review.

The results revealed that these cancers were at a more advanced stage when diagnosed, were more often small cell lung cancers and less often adenocarcinoma. The analysis also showed that this type of cancer was more common among males and those with a history of smoking.

Lead author, Dr. Paul Kvale from the Henry Ford Hospital in the USA, said: "These findings have helped us to understand the characteristics of this type of lung cancer, pointing out features which make them different from lung cancers that can be detected by a chest x-ray screening programme. The results add to the evidence that a screening programme using x-rays is not suitable for lung cancer, as this this more aggressive form of the disease will be missed.

"By increasing our understanding of true interval cancers, we can help to improve screening techniques in the future."


Story Source:

The above story is based on materials provided by European Lung Foundation. Note: Materials may be edited for content and length.


Cite This Page:

European Lung Foundation. "Study sheds light on lung cancers that are undetected by radiograph." ScienceDaily. ScienceDaily, 2 September 2012. <www.sciencedaily.com/releases/2012/09/120902184922.htm>.
European Lung Foundation. (2012, September 2). Study sheds light on lung cancers that are undetected by radiograph. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2012/09/120902184922.htm
European Lung Foundation. "Study sheds light on lung cancers that are undetected by radiograph." ScienceDaily. www.sciencedaily.com/releases/2012/09/120902184922.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Cases Keep Coming for Monrovia's Island Hospital

Ebola Cases Keep Coming for Monrovia's Island Hospital

AFP (Oct. 1, 2014) A look inside Monrovia's Island Hospital, a key treatment centre in the fight against Ebola in Liberia's capital city. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com
Ebola Puts Stress on Liberian Health Workers

Ebola Puts Stress on Liberian Health Workers

AP (Oct. 1, 2014) The Ebola outbreak is putting stress on first responders in Liberia. Ambulance drivers say they are struggling with chronic shortages of safety equipment and patients who don't want to go to the hospital. (Oct. 1) Video provided by AP
Powered by NewsLook.com
Doctors Reassure Public Ebola Patient Won't Cause Outbreak

Doctors Reassure Public Ebola Patient Won't Cause Outbreak

Newsy (Sep. 30, 2014) After the announcement that the first U.S. patient had been diagnosed with Ebola, doctors were quick to say a U.S. outbreak is highly unlikely. Video provided by Newsy
Powered by NewsLook.com
TX Hospital Confirms Patient Admitted With Ebola

TX Hospital Confirms Patient Admitted With Ebola

AP (Sep. 30, 2014) Medical officials from Texas Health Presbyterian Hospital confirm they are treating a patient with the Ebola virus, the first case found in the US. (Sept. 30 Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins